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22,033 Newest Publications in proceedings of the national academy of sciences current issue

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Correction for Schulz et al., TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle [Correction]

17-May-2016 | Proceedings of the National Academy of Sciences current issue, 2016

BIOCHEMISTRY Correction for “TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle,” by Sarah Schulz, Andreas Gietl, Katherine Smollett, Philip Tinnefeld, Finn Werner, and Dina Grohmann, which appeared in issue 13, March 29, 2016, of Proc Natl Acad Sci USA ...

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Light-induced actuating nanotransducers [Applied Physical Sciences]

17-May-2016 | Tao Ding; Ventsislav K. Valev; Andrew R. Salmon; Chris J. Forman; Stoyan K. Smoukov; Oren A. Scherman; Daan Frenkel; ..., Proceedings of the National Academy of Sciences current issue, 2016

Nanoactuators and nanomachines have long been sought after, but key bottlenecks remain. Forces at submicrometer scales are weak and slow, control is hard to achieve, and power cannot be reliably supplied. Despite the increasing complexity of nanodevices such as DNA origami and molecular machines, ...

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Extreme cellular adaptations and cell differentiation required by a cyanobacterium for carbonate excavation [Microbiology]

17-May-2016 | Brandon Scott Guida; Ferran Garcia-Pichel, Proceedings of the National Academy of Sciences current issue, 2016

Some cyanobacteria, known as euendoliths, excavate and grow into calcium carbonates, with their activity leading to significant marine and terrestrial carbonate erosion and to deleterious effects on coral reef and bivalve ecology. Despite their environmental relevance, the mechanisms by which ...

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Study retention as bias reduction in a hard-to-reach population [Social Sciences]

17-May-2016 | Bruce Western; Anthony Braga; David Hureau; Catherine Sirois, Proceedings of the National Academy of Sciences current issue, 2016

Collecting data from hard-to-reach populations is a key challenge for research on poverty and other forms of extreme disadvantage. With data from the Boston Reentry Study (BRS), we document the extreme marginality of released prisoners and the related difficulties of study retention and analysis. ...

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Efficient analysis of mouse genome sequences reveal many nonsense variants [Genetics]

17-May-2016 | Sophie Steeland; Steven Timmermans; Sara Van Ryckeghem; Paco Hulpiau; Yvan Saeys; Marc Van Montagu; Roosmarijn E. Va ..., Proceedings of the National Academy of Sciences current issue, 2016

Genetic polymorphisms in coding genes play an important role when using mouse inbred strains as research models. They have been shown to influence research results, explain phenotypical differences between inbred strains, and increase the amount of interesting gene variants present in the many ...

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Increased androgenic sensitivity in the hind limb muscular system marks the evolution of a derived gestural display [Evolution]

17-May-2016 | Lisa A. Mangiamele; Matthew J. Fuxjager; Eric R. Schuppe; Rebecca S. Taylor; Walter Hödl; Doris Preininger, Proceedings of the National Academy of Sciences current issue, 2016

Physical gestures are prominent features of many species’ multimodal displays, yet how evolution incorporates body and leg movements into animal signaling repertoires is unclear. Androgenic hormones modulate the production of reproductive signals and sexual motor skills in many vertebrates; ...

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Novel DLK-independent neuronal regeneration in Caenorhabditis elegans shares links with activity-dependent ectopic outgrowth [Neuroscience]

17-May-2016 | Samuel H. Chung; Mehraj R. Awal; James Shay; Melissa M. McLoed; Eric Mazur; Christopher V. Gabel, Proceedings of the National Academy of Sciences current issue, 2016

During development, a neuron transitions from a state of rapid growth to a stable morphology, and neurons within the adult mammalian CNS lose their ability to effectively regenerate in response to injury. Here, we identify a novel form of neuronal regeneration, which is remarkably independent of ...

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Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation [Immunology and Inflammation]

17-May-2016 | Kenta Shinoda; Kiyoshi Hirahara; Tomohisa Iinuma; Tomomi Ichikawa; Akane S. Suzuki; Kaoru Sugaya; Damon J. Tumes; He ..., Proceedings of the National Academy of Sciences current issue, 2016

Memory CD4+ T helper (Th) cells are central to long-term protection against pathogens, but they can also be pathogenic and drive chronic inflammatory disorders. How these pathogenic memory Th cells are maintained, particularly at sites of local inflammation, remains unclear. We found that ectopic ...

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Origins of ultralow velocity zones through slab-derived metallic melt [Earth, Atmospheric, and Planetary Sciences]

17-May-2016 | Jiachao Liu; Jie Li; Rostislav Hrubiak; Jesse S. Smith, Proceedings of the National Academy of Sciences current issue, 2016

Understanding the ultralow velocity zones (ULVZs) places constraints on the chemical composition and thermal structure of deep Earth and provides critical information on the dynamics of large-scale mantle convection, but their origin has remained enigmatic for decades. Recent studies suggest that ...

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Transactional information is remarkably revelatory [Computer Sciences]

17-May-2016 | Susan Landau, Proceedings of the National Academy of Sciences current issue, 2016

When Edward Snowden revealed that the United States government had been collecting domestic communications metadata in bulk, the administration responded that there was no great concern. The data were only how long, when, and which number called which, not what participants said. Two days after ...

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