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17,682 Newest Publications in proceedings of the national academy of sciences current issue

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Family environment and the malleability of cognitive ability: A Swedish national home-reared and adopted-away cosibling control study [Psychological and Cognitive Sciences]

14-Apr-2015 | Kenneth S. Kendler; Eric Turkheimer; Henrik Ohlsson; Jan Sundquist; Kristina Sundquist, Proceedings of the National Academy of Sciences current issue, 2015

Cognitive ability strongly aggregates in families, and prior twin and adoption studies have suggested that this is the result of both genetic and environmental factors. In this study, we used a powerful design—home-reared and adopted-away cosibling controls—to investigate the role of the rearing ...

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Structural basis for the geometry-driven localization of a small protein [Microbiology]

14-Apr-2015 | Richard L. Gill Jr.; Jean-Philippe Castaing; Jen Hsin; Irene S. Tan; Xingsheng Wang; Kerwyn Casey Huang; Fang Tian; ..., Proceedings of the National Academy of Sciences current issue, 2015

In bacteria, certain shape-sensing proteins localize to differently curved membranes. During sporulation in Bacillus subtilis, the only convex (positively curved) surface in the cell is the forespore, an approximately spherical internal organelle. Previously, we demonstrated that SpoVM localizes ...

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Continental crust beneath southeast Iceland [Earth, Atmospheric, and Planetary Sciences]

14-Apr-2015 | Trond H. Torsvik; Hans E. F. Amundsen; Reidar G. Trønnes; Pavel V. Doubrovine; Carmen Gaina; Nick J. Kusznir; Bernha ..., Proceedings of the National Academy of Sciences current issue, 2015

The magmatic activity (0–16 Ma) in Iceland is linked to a deep mantle plume that has been active for the past 62 My. Icelandic and northeast Atlantic basalts contain variable proportions of two enriched components, interpreted as recycled oceanic crust supplied by the plume, and subcontinental ...

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Sphingomyelin distribution in lipid rafts of artificial monolayer membranes visualized by Raman microscopy [Chemistry]

14-Apr-2015 | Jun Ando; Masanao Kinoshita; Jin Cui; Hiroyuki Yamakoshi; Kosuke Dodo; Katsumasa Fujita; Michio Murata; Mikiko Sodeoka, Proceedings of the National Academy of Sciences current issue, 2015

Sphingomyelin (SM) and cholesterol (chol)-rich domains in cell membranes, called lipid rafts, are thought to have important biological functions related to membrane signaling and protein trafficking. To visualize the distribution of SM in lipid rafts by means of Raman microscopy, we designed and ...

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Diversity partitioning during the Cambrian radiation [Evolution]

14-Apr-2015 | Lin Na; Wolfgang Kiessling, Proceedings of the National Academy of Sciences current issue, 2015

The fossil record offers unique insights into the environmental and geographic partitioning of biodiversity during global diversifications. We explored biodiversity patterns during the Cambrian radiation, the most dramatic radiation in Earth history. We assessed how the overall increase in global ...

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Autoinhibition of MDMX by intramolecular p53 mimicry [Biochemistry]

14-Apr-2015 | Lihong Chen; Wade Borcherds; Shaofang Wu; Andreas Becker; Ernst Schonbrunn; Gary W. Daughdrill; Jiandong Chen, Proceedings of the National Academy of Sciences current issue, 2015

The p53 inhibitor MDMX is controlled by multiple stress signaling pathways. Using a proteolytic fragment release (PFR) assay, we detected an intramolecular interaction in MDMX that mechanistically mimics the interaction with p53, resulting in autoinhibition of MDMX. This mimicry is mediated by a ...

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Multiple mechanisms limit meiotic crossovers: TOP3{alpha} and two BLM homologs antagonize crossovers in parallel to FANCM [Genetics]

14-Apr-2015 | Mathilde Séguéla-Arnaud; Wayne Crismani; Cécile Larchevêque; Julien Mazel; Nicole Froger; Sandrine Choinard; Afef Le ..., Proceedings of the National Academy of Sciences current issue, 2015

Meiotic crossovers (COs) have two important roles, shuffling genetic information and ensuring proper chromosome segregation. Despite their importance and a large excess of precursors (i.e., DNA double-strand breaks, DSBs), the number of COs is tightly regulated, typically one to three per ...

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Correction for Sagi et al., Nitric oxide regulates synaptic transmission between spiny projection neurons [Correction]

07-Apr-2015 | Proceedings of the National Academy of Sciences current issue, 2015

NEUROSCIENCE Correction for “Nitric oxide regulates synaptic transmission between spiny projection neurons,” by Yotam Sagi, Myriam Heiman, Jayms D. Peterson, Sergei Musatov, Michael G. Kaplitt, Dalton J. Surmeier, Nathaniel Heintz, and Paul Greengard, which appeared in issue 49, December 9, 2014, ...

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Trichodesmium genome maintains abundant, widespread noncoding DNA in situ, despite oligotrophic lifestyle [Evolution]

07-Apr-2015 | Nathan Walworth; Ulrike Pfreundt; William C. Nelson; Tracy Mincer; John F. Heidelberg; Feixue Fu; John B. Waterbury; ..., Proceedings of the National Academy of Sciences current issue, 2015

Understanding the evolution of the free-living, cyanobacterial, diazotroph Trichodesmium is of great importance because of its critical role in oceanic biogeochemistry and primary production. Unlike the other >150 available genomes of free-living cyanobacteria, only 63.8% of the Trichodesmium ...

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Carbon monoxide as a metabolic energy source for extremely halophilic microbes: Implications for microbial activity in Mars regolith [Microbiology]

07-Apr-2015 | Gary M. King, Proceedings of the National Academy of Sciences current issue, 2015

Carbon monoxide occurs at relatively high concentrations (≥800 parts per million) in Mars’ atmosphere, where it represents a potentially significant energy source that could fuel metabolism by a localized putative surface or near-surface microbiota. However, the plausibility of CO oxidation under ...

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