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218 Newest Publications of BioMed Central
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Evaluation of phenolic contents and antioxidant activity of various solvent extracts of Sonchus asper (L.) Hill
06-02-2012 | Rahmat Ali Khan, Muhammad Rashid Khan, Sumaira Sahreen, Mushtaq Ahmed, Chemistry Central Journal , 2012
Background: Sonchus asper (SA) is traditionally used for the treatment of various ailments associated with liver, lungs and kidneys. This study was aimed to investigate the therapeutic potential of nonpolar (hexane, SAHE; ethyl acetate, SAEE and chloroform, SACE) and polar (methanol, SAME) ...
Identification of Avian Wax Synthases
04-02-2012 | Eva-Maria Biester, Janine Hellenbrand, Jens Gruber, Mats Hamberg, Margrit Frentzen, BMC Biochemistry, 2012
Background: Bird species show a high degree of variation in the composition of their preen gland waxes. For instance, galliform birds like chicken contain fatty acid esters of 2,3-alkanediols, while Anseriformes like goose or Strigiformes like barn owl contain wax monoesters in their preen ...
Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate
03-02-2012 | Ibrahim A Darwish, Mona M Al-Shehri, Manal A El-Gendy, Chemistry Central Journal , 2012
This study represents the first report on the development of a novel spectrophotometric method for determination of cinacalcet hydrochloride (CIN) in its tablet dosage forms. Studies were carried out to investigate the reaction between CIN and 1,2-naphthoquinone-4-sulphonate (NQS) reagent. In ...
Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro
31-01-2012 | Jana Pytelkova, Martin Lepsik, Miloslav Sanda, Pavel Talacko, Lucie Maresova, Michael Mares, BMC Biochemistry, 2012
Background: Enzymatic allergens of storage mites that contaminate stored food products are poorly characterized. We describe biochemical and immunological properties of the native alpha-amylase allergen Aca s 4 from Acarus siro, a medically important storage mite. Results: A. siro produced a ...
Comparison of sterols and fatty acids in two species of Ganoderma
31-01-2012 | Guang-ping Lv, Jing Zhao, Jin-ao Duan, Yu-ping Tang, Shao-ping Li, Chemistry Central Journal , 2012
Background: Two species of Ganoderma, G. sinense and G. lucidum, are used as Lingzhi in China. Howerver, the content of triterpenoids and polysaccharides, main actives compounds, are significant different, though the extracts of both G. lucidum and G. sinense have antitumoral proliferation ...
Development and Validation of a repharsed Phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma
26-01-2012 | Nahed M El-Enany, Amina A Abdelal, Fathalla F Belal, Yoshinori I Itoh, Mitsuhiro N Nakamura, Chemistry Central Journal , 2012
Background: Rosiglitazone (ROZ) and glimepiride (GLM) are antidiabetic agents used in the treatment of type 2 diabetes mellitus. A survey of the literature reveals that only one spectrophotometric method has been reported for the simultaneous determination of ROS and GLM in pharmaceutical ...
Hyaluronan synthase mediates dye translocation across liposomal membranes
25-01-2012 | Andria P Medina, Jialing Lin, Paul H Weigel, BMC Biochemistry, 2012
Background: Hyaluronan (HA) is made at the plasma membrane and secreted into the extracellular medium or matrix by phospolipid-dependent hyaluronan synthase (HAS), which is active as a monomer. Since the mechanism by which HA is translocated across membranes is still unresolved, we assessed ...
Comparative researches on two direct transmethylation without prior extraction methods for fatty acids analysis in vegetal matrix with low fat content
23-01-2012 | Monica Harmanescu, Chemistry Central Journal , 2012
Background: The aim of our work was to compare two methods, both based on direct transmethylation with different reagents, BF3/MeOH (boron trifluoride in methanol) or HCl/MeOH (hydrochloride acid in methanol), in acid catalysis, without prior extraction, to find the fast, non-expensive but ...
Stress degradation studies and development of stability-indicating TLC-densitometry method for determination of prednisolone acetate and chloramphenicol in their individual and combined pharmaceutical formulations
22-01-2012 | Syed G. Musharraf, Urooj Fatima, Rahat Sultana, Chemistry Central Journal , 2012
A rapid and reproducible stability indicating TLC method was developed for the determination of prednisolone acetate and chloramphenicol in presence of their degraded products. Uniform degradation conditions were maintained by refluxing sixteen reaction mixtures for two hours at 80 oC using ...
Disposable screen-printed sensors for determination of duloxetine hydrochloride
21-01-2012 | Nawal A Alarfaj, Reda A Ammar, Maha F El-Tohamy, Chemistry Central Journal , 2012
A screen-printed disposable electrode system for the determination of duloxetine hydrochloride (DL) was developed using screen-printing technology. Homemade printing has been characterized and optimized on the basis of effects of the modifier and plasticizers. The fabricated bi-electrode ...
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