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775 Newest Publications of de Gruyter
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Serum concentration of neopterin on admission does not improve the diagnostic performance of highly-sensitive troponin I
13-12-2011 | Martina Montagnana; Giuseppe Lippi; Elisa Danese; Gian Luca Salvagno; Gianfranco Cervellin; Gian Cesare Guidi, Clinical Chemistry , 2011
Clinical Chemistry and Laboratory Medicine, Volume 0, Issue 0, Page -, Ahead of Print.
Ultrasound markers for the detection of women at risk of developing pre-eclampsia
13-12-2011 | Guillaume Macé; Evelyne Cynober; Bruno Carbonne, Clinical Chemistry , 2011
Abstract Pre-eclampsia (PE) is a consequence of an abnormal placental invasion. Uterine artery Doppler (Ut-AD) is directly related to trophoblastic invasion of the spiral arteries, which occurs before 18 weeks’ gestation. A correct interpretation of Ut-AD indices and waveform patterns ...
Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors
13-12-2011 | Igor Mindukshev; Stepan Gambaryan; Linda Kehrer; Claudia Schuetz; Anna Kobsar; Natalia Rukoyatkina; Viacheslav ..., Clinical Chemistry , 2011
Abstract Background: Determinations of platelet receptor functions are indispensable diagnostic indicators of cardiovascular and hemostatic diseases including hereditary and acquired receptor defects and receptor responses to drugs. However, presently available techniques for assessing ...
Serum mesothelin and megakaryocyte potentiating factor in pancreatic and biliary cancers
13-12-2011 | Elad Sharon; Jingli Zhang; Kevin Hollevoet; Seth M. Steinberg; Ira Pastan; Masanori Onda; Jochen Gaedcke; B. ..., Clinical Chemistry , 2011
Abstract Background: Tumor mesothelin overexpression is present in different malignancies, including the majority of patients with pancreatic or biliary cancers. The objective of this study was to evaluate the use of shed serum mesothelin and megakaryocyte potentiating factor (MPF) ...
Faecal haemoglobin concentrations by gender and age: implications for population-based screening for colorectal cancer
13-12-2011 | Paula J. McDonald; Judith A. Strachan; Jayne Digby; Robert J.C. Steele; Callum G. Fraser, Clinical Chemistry , 2011
Abstract Background: Faecal immunochemical tests (FIT) are becoming widely used in colorectal cancer screening. Estimation of faecal haemoglobin concentration in a large group prompted an observational study on gender and age. Methods: A single estimate of faecal haemoglobin concentration was ...
Comparison of different collection procedures and two methods for DNA isolation from saliva
13-12-2011 | Jaroslava Durdiaková; Natália Kamodyová; Daniela Ostatníková; Barbora Vlková; Pete ..., Clinical Chemistry , 2011
Abstract Background: The non-invasive, flexible and easy sample collection makes saliva an interesting source of DNA for research and diagnostic purposes. The aim of our study was to find the most suitable collection method for biological material from the oral cavity and the most effective ...
A comparative analysis of the Iris iQ200 with manual microscopy as a diagnostic tool for dysmorphic erythrocytes in urine
13-12-2011 | Leonie A. Boven; Hans Kemperman; Ayşe Y. Demir, Clinical Chemistry , 2011
Clinical Chemistry and Laboratory Medicine, Volume 0, Issue 0, Page -, Ahead of Print.
Demasking of epithelial cell adhesion molecule (EpCAM) on circulating epithelial tumor cells by Tween®20 treatment in breast cancer patients
13-12-2011 | Katya Hekimian; Ernst-Ludwig Stein; Ulrich Pachmann; Katharina Pachmann, Clinical Chemistry , 2011
Abstract Background: The epithelial cell adhesion molecule (EpCAM) embedded in the plasma membrane of circulating epithelial tumor cells (CETC) is used for detection and enrichment of circulating tumor cells in peripheral blood and as a target for anti-epithelial antibodies elicited during ...
Soluble transcobalamin receptor, sCD320, is present in human serum and relates to serum cobalamin – establishment and validation of an ELISA
13-12-2011 | Johan Frederik Berg Arendt; Edward V. Quadros; Ebba Nexo, Clinical Chemistry , 2011
Abstract Background: The cell-surface receptor, TCblR/CD320, binds and internalizes transcobalamin-bound cobalamin. So far, no assay has been developed in order to quantify the soluble form of the receptor. Methods: This study developed an ELISA employing a monoclonal antibody that recognized ...
Monitoring quality indicators in laboratory medicine does not automatically result in quality improvement
13-12-2011 | Laura Sciacovelli; Oswald Sonntag; Andrea Padoan; Carlo Federico Zambon; Paolo Carraro; Mario Plebani, Clinical Chemistry , 2011
Abstract Background: Data on quality indicators (QIs) should be collected over time in order to identify and continuously monitor clinical laboratory performance and to improve patient safety by identifying and implementing effective interventions. The aim of the present study was to ...
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