My watch list
my.chemeurope.com  
Login  

1,772 Newest Publications of Portland Press

rss
matching the following criteria

Comparisons of subunit 5A and 5B isoenzymes of yeast cytochrome c oxidase

15-12-2014 | Dodia R; Meunier B; Kay CWM; Rich PR, Biochemical Journal, 2014

Subunit 5 of Saccharomyces cerevisiae cytochrome c oxidase (CcO) is essential for assembly and has two isoforms, 5A and 5B. 5A is expressed under normoxic conditions, whereas 5B is expressed at very low oxygen tensions. As a consequence, COX5A-deleted strains (Δcox5A) have no or only low levels ...

more

A context-independent N-glycan signal targets the misfolded extracellular domain of Arabidopsis STRUBBELIG to endoplasmic-reticulum-associated degradation

15-12-2014 | Huttner S; Veit C; Vavra U; Schoberer J; Dicker M; Maresch D; Altmann F; Strasser R, Biochemical Journal, 2014

N-glycosylation of proteins plays an important role in the determination of the fate of newly synthesized glycoproteins in the endoplasmic reticulum (ER). Specific oligosaccharide structures recruit molecular chaperones that promote folding or mannose-binding lectins that assist in the clearance ...

more

TREHALOSE-6-PHOSPHATE SYNTHASE 1 is not the only active TPS in {Less than}i{Greater than}Arabidopsis thaliana.{Less than}/i{Greater than}

12-12-2014 | Delorge I; Figueroa C; Feil R; Lunn J; Van Dijck P, Biochemical Journal, 2014

Trehalose metabolism is essential for normal growth and development in higher plants. It is synthesized in a two-step pathway catalyzed by trehalose-6-phosphate (Tre6P) synthase (TPS) and trehalose phosphatase. Arabidopsis thaliana has 11 TPS or TPS-like proteins, which belong to two distinct ...

more

TARP {gamma}-8 glycosylation regulates the surface expression of AMPA receptors

11-12-2014 | Zheng C; Chang K; Suh Y; Roche K, Biochemical Journal, 2014

Transmembrane AMPA receptor regulatory protein (TARP) γ-8 is an auxiliary subunit of AMPA receptors that is widely distributed in the hippocampus. It has been shown that TARP γ-8 promotes surface expression of AMPA receptors; however, how TARP γ-8 regulates the expression of AMPA receptors ...

more

Catalytic surface radical in dye-decolorizing peroxidase: A computational, spectroscopic and site-directed mutagenesis study

11-12-2014 | Linde D; Pogni R; Canellas M; Lucas F; Guallar V; Baratto M; Sinicropi A; S{a}ez-jim{e}nez V; Coscolin C; Romero A; ..., Biochemical Journal, 2014

Dye-decolorizing peroxidase (DyP) of Auricularia auricula-judae has been expressed in E. coli, as a representative for new DyP family, and subjected to mutagenesis, spectroscopic, crystallographic and computational studies. The crystal structure of DyP shows a buried haem cofactor, and surface ...

more

Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

09-12-2014 | Bett J; Ritorto M; Ewan R; Jaffray E; Virdee S; Chin J; Knebel A; Kurz T; Trost M; Tatham M; Hay R, Biochemical Journal, 2014

Modification of proteins with ubiquitin (Ub) occurs through a variety of topologically distinct Ub linkages, including Ube2W-mediated monoubiquitylation of N-terminal alpha amines to generate peptide-linked linear mono-Ub fusions. Protein ubiquitylation can be reversed by the action of ...

more

Kinetic Characterization of a Cocaine Hydrolase Engineered from Mouse Butyrylcholinesterase

08-12-2014 | Chen X; Huang X; Geng L; Xue L; Hou S; Zheng X; Brimijoin S; Zheng F; Zhan C, Biochemical Journal, 2014

Mouse butyrylcholinesterase (mBChE) and an mBChE-based cocaine hydrolase (mCocH, i.e. the A199S/S227A/S287G/A328W/Y332G mutant) have been characterized for their catalytic activities against cocaine, i.e. naturally occurring (-)-cocaine, in comparison with the corresponding human BChE (hBChE) and ...

more

Expression of different bacterial cytotoxins is controlled by two global transcription factors, CRP and Fis, that cooperate in a shared-recruitment mechanism.

08-12-2014 | Rossiter A; Godfrey R; Connolly J; Busby S; Henderson I; Browning D, Biochemical Journal, 2014

Pet is a cytotoxic autotransporter protein secreted by the pathogenic Enteroaggregative Escherichia coli strain 042. Expression of Pet is co-dependent on two global transcription regulators: CRP (cyclic AMP receptor protein) and Fis (factor for inversion stimulation). At the pet promoter CRP ...

more

Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase

04-12-2014 | Hou X; Wu W; Duan X; Liu N; Li H; Fu J; Dou S; Li M; Xi X, Biochemical Journal, 2014

Recent advances in G-quadruplex (G4) studies have confirmed that G4 structures exist in living cells and may have detrimental effects on various DNA transactions. How helicases resolve G4, however, has just begun to be studied and remains largely unknown. Here we use single-molecule fluorescence ...

more

Cu{Less than}sup{Greater than}2{+}{Less than}/sup{Greater than} accentuates distinct misfolding for A{beta}{Less than}sub{Greater than}(1-40) {Less than}/sub{Greater than}and A{beta}{Less than}sub{Greater than}(1-42) {Less than}/sub{Greater than}peptides, and potentiates membrane disruption

04-12-2014 | Matheou C; Younan N; Viles J, Biochemical Journal, 2014

Central to Alzheimer’s Disease is the misfolding of amyloid-beta (Aβ) peptide, which generates an assorted population of amorphous aggregates, oligomers and fibres. Metal ion homeostasis is disrupted in the brains of sufferers of Alzheimer’s disease and causes heightened Alzheimer’s disease ...

more

Page 1 From 178
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE