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2,860 Newest Publications about the topic drug delivery

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Pneumatic-aided micro-molding for flexible fabrication of homogeneous and heterogeneous cell-laden microgels

25-May-2016 | Chao Ma; Chang Tian; Lei Zhao; Jinyi Wang, Lab on a Chip, 2016

Microgels are favorable for numerous applications such as drug delivery, biomaterials science and tissue engineering. Conventionally, photolithographic methods and micro-molding techniques are extensively exploited to prepare microgels; however, they are, respectively, limited to ...

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The Recent Progress in the Preparation of Chitosan 6-OH Immobilized Cyclodextrin and its Application

24-May-2016 | Chen, Yu; Song, Ganlin; Qiu, Yihui; Tan, Huimin; Ye, Yanchun; Guo, Yanwen, Mini-Reviews in Organic Chemistry, 2016

Abstract: Chitosan is an ideal biomaterial due to its excellent comprehensive properties. Cyclodextrins bearing the cavity structure and amphiphilic properties have become the focus of supramolecular chemistry. The chemical immobilization of cyclodextrin on the chitosan skeleton can be a ...

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Selection of Lung Cancer-Specific Landscape Phage for Targeted Drug Delivery

24-May-2016 | W. Gillespie, James; Wei, Lixia; A. Petrenko, Valery, Combinatorial Chemistry, 2016

Abstract: Cancer cell-specific diagnostic or therapeutic tools are commonly believed to significantly increase the success rate of cancer diagnosis and targeted therapies. To extend the repertoire of available cancer cell-specific phage fusion proteins and study their efficacy as navigating ...

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Molecules, Vol. 21, Pages 672: Positively Charged Nanostructured Lipid Carriers and Their Effect on the Dissolution of Poorly Soluble Drugs

20-May-2016 | Choi, Kyeong-Ok ; Choe, Jaehyeog ; Suh, Seokjin ; Ko, Sanghoon, Molecules, 2016

The objective of this study is to develop suitable formulations to improve the dissolution rate of poorly water soluble drugs. We selected lipid-based formulation as a drug carrier and modified the surface using positively charged chitosan derivative (HTCC) to increase its water solubility and ...

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Nanoengineered Templated Polymer Particles: Navigating the Biological Realm

20-May-2016 | Jiwei Cui; Joseph J. Richardson; Mattias Björnmalm; Matthew Faria; Frank Caruso, Accounts of Chemical Research, 2016

ConspectusNanoengineered materials offer tremendous promise for developing the next generation of therapeutics. We are transitioning from simple research questions, such as “can this particle eradicate cancer cells?” to more sophisticated ones like “can we design a particle to preferentially ...

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Size‐controlled/Surface‐Functionalized Polystyrene Nanospheres with Good Biocompatibility and High Encapsulation Efficiency of Cyclosporin A via Miniemulsion Polymerization in One Step

19-May-2016 | Xiaoli Song, Fangfang Yang, Ling Li, Aiping Zhu, Chinese Journal of Chemistry, 2016

Abstract In this paper, size‐controlled and surface‐functionalized RhB‐labeled and Cyclosporin A (CsA)‐loaded polystyrene (PS) nanospheres were successfully synthesized via miniemulsion polymerization. The biophysical properties of PEG functionalized PS nanospheres from protein adsorption, ...

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Highly Emissive Nd3+‐Sensitized Multilayered Upconversion Nanoparticles for Efficient 795 nm Operated Photodynamic Therapy

18-May-2016 | Feng Lu, Lin Yang, Yujie Ding, Jun‐Jie Zhu, Advanced Functional Materials, 2016

Photodynamic therapy (PDT) is a noninvasive and site‐specific therapeutic technique for the clinical treatment of various of superficial diseases. In order to tuning the operation wavelength and improve the tissue penetration of PDT, rare‐earth doped upconversion nanoparticles (UCNPs) with ...

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Elucidating Dominant Pathways of the Nano-particle Self-Assembly Process

18-May-2016 | Xiangze Zeng; Bin Li; Qin Qiao; Lizhe Zhu; Zhong-Yuan Lu; Xuhui Huang, Physical Chemistry Chemical Physics, 2016

Self-assembly processes play a key role in fabricating functional nano-structures with wide application in drug delivery and micro-reactors. In addition to the thermodynamics, the kinetics of the self-assembled nano-structures also play an important role in determining the formed structures. ...

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The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use

18-May-2016 | Iglesias, Daniel; Bosi, Susanna; Melchionna, Michele; Da Ros, Tatiana; Marchesan, Silvia, Current Topics in Medicinal Chemistry, 2016

Abstract: In recent years, we have witnessed to fast developments in the medicinal field of hydrogels containing various forms of integrated nanostructured carbon that adds interesting mechanical, thermal, and electronic properties. Besides key advances in tissue engineering (especially for ...

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Materials, Vol. 9, Pages 383: Nanoparticles for Control of Biofilms of Acinetobacter Species

18-May-2016 | Singh, Richa ; Nadhe, Shradhda ; Wadhwani, Sweety ; Shedbalkar, Utkarsha ; Chopade, Balu Ananda, Materials, 2016

Biofilms are the cause of 80% of microbial infections. Acinetobacter species have emerged as multi- and pan-drug-resistant bacteria and pose a great threat to human health. These act as nosocomial pathogens and form excellent biofilms, both on biotic and abiotic surfaces, leading to severe ...

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