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3,293 Newest Publications about the topic drug delivery

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Lipid-polymer hybrid nanoparticles for synergistic drug delivery to overcome cancer drug resistance

18-Jan-2017 | Shao-Qi Zeng; Yi-Zhen Chen; Yong Chen; hong Liu, New Journal of Chemistry, 2017

To overcome the major obstacle of successful cancer chemotherapy, multidrug resistance (MDR), we prepared lipid-shell and polymer-core nanoparticles (LPNP) to co-deliver an anticancer drug and a drug resistance inhibitor to achieve a synergistic effect and to overcome cancer drug resistance. LPNP ...

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Facile Fabrication of a Magnetically Smart PTX-Loaded Cys-Fe3O4/CuS@BSA Nano-drug for Imaging-guided Chemo-photothermal Therapy

18-Jan-2017 | Lanfang Ren; Xijian Liu; Qian Wang; Lijuan Zhang; Guoying Deng; Feng Zhou; Jie Lu, Dalton Transactions, 2017

In the study, a multifunctional Nano-drug (PTX-Loaded Cys-Fe3O4/CuS@BSA nanocomposite), which does well at hydrophobic drug delivery, magnetic resonance imaging (MRI) and chemo-photothermal combination therapy, has been successfully synthesized via a facile one-step method with several ...

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BSA-Coated Fluorescent Organic-Inorganic Hybrid Silica Nanoparticles: Preparation, and Drug Delivery

18-Jan-2017 | zengming yang; Hengchang Ma; Zijie Jin; Haiying Cao; Lei Lei; Yucheng Ma; Ziqiang Lei, New Journal of Chemistry, 2017

It is much desirable to engineering the cargo release vehicles with the efficient cargo loading capability, and the controlled drug delivery ability, as well as the bio-compatible construction materials. Herein, an inorganic-organic hybrid composite DNDT&SiO2–NH2@BSA was established by two steps. ...

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Chitosan-based magnetic/fluorescent nanocomposites for cell labelling and controlled drug release

18-Jan-2017 | Yongling Ding; Hong Yin; Shen Shirley; Kang-ning Sun; Futian Liu, New Journal of Chemistry, 2017

Chitosan-based drug delivery system, composed of Fe3O4magnetic nanoparticles (MNPs), CdTe@ZnS quantum dots (QDs) and anti-cancer drug doxorubicin (DOX) was designed and fabricated. The surfaces of MNPs were modified by carboxymethyl chitosan (CMCS) to minimise the possible fluorescence quenching ...

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Single component image guided ‘On-demand’ drug delivery system for early stage prostate cancer

15-Jan-2017 | Author(s): Sandipan Biswas, Joyjyoti Das, Shrabani Barman, Sk. Sheriff Shah, Moumita Gangopadhyay, Tapas K ..., Sensors and Actuators B: Chemical, 2017

Publication date: June 2017 Source:Sensors and Actuators B: Chemical, Volume 244 Author(s): Sandipan Biswas, Joyjyoti Das, Shrabani Barman, Sk. Sheriff Shah, Moumita Gangopadhyay, Tapas K. Maiti, N.D. Pradeep Singh The early stage detection, diagnosis and treatment of prostate ...

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Frontispiece: Photo‐Modulated Therapeutic Protein Release from a Hydrogel Depot Using Visible Light

13-Jan-2017 | Johan S. Basuki, Fengxiang Qie, Xavier Mulet, Randy Suryadinata, Aditya V. Vashi, Yong Y. Peng, Lingli Li, Xiaojuan ..., Angewandte Chemie International Edition, 2017

Drug Delivery Systems A light‐triggered drug delivery system based on Au nanoparticles inside an agarose hydrogel is presented by T. W. Tan, T. C. Hughes et al. in their Communication on page 966 ff. Visible light induces softening of the hydrogel matrix to release pre‐loaded therapeutics.

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Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger

13-Jan-2017 | E. Oude Blenke; M. Sleszynska; M. J. W. Evers; G. Storm; N. I. Martin; E. Mastrobattista, Bioconjugate Chemistry, 2017

Endosomolytic peptides are often coupled to drug delivery systems to enhance endosomal escape, which is crucial for the delivery of macromolecular drugs that are vulnerable to degradation in the endolysosomal pathway. Melittin is a 26 amino acid peptide derived from bee venom that has a very high ...

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An Exonuclease III‐Powered, On‐Particle Stochastic DNA Walker

12-Jan-2017 | Xiangmeng Qu, Dan Zhu, Guangbao Yao, Shao Su, Jie Chao, Huajie Liu, Xiaolei Zuo, Lihua Wang, Jiye Shi, Lianhui Wang, ..., Angewandte Chemie International Edition, 2017

Abstract DNA‐based machines have attracted rapidly growing interest owing to their potential in drug delivery, biocomputing, and diagnostic applications. Herein, we report a type of exonuclease III (Exo III)‐powered stochastic DNA walker that can autonomously move on a spherical nucleic acid ...

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Two‐Dimensional Nanomaterials for Cancer Nanotheranostics

11-Jan-2017 | Yongjiu Chen, Yakun Wu, Bingbing Sun, Sijin Liu, Huiyu Liu, Small, 2017

Emerging nanotechnologies show unprecedented advantages in accelerating cancer theranostics. Among them, two‐dimensional nanomaterials (2DNMs) represent a novel type of material with versatile physicochemical properties that have enabled a new horizon for applications in both cancer diagnosis ...

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IJERPH, Vol. 14, Pages 66: Bioactive Nanocomposites for Tissue Repair and Regeneration: A Review

11-Jan-2017 | Bramhill, Jane ; Ross, Sukunya ; Ross, Gareth, International Journal of Environmental Research and Public Health, 2017

This review presents scientific findings concerning the use of bioactive nanocomposites in the field of tissue repair and regeneration. Bioactivity is the ability of a material to incite a specific biological reaction, usually at the boundary of the material. Nanocomposites have been shown to be ...

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