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3,418 Newest Publications about the topic drug delivery

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Nanocarriers for Effective Brain Drug Delivery

19-Apr-2017 | Comoglu, Tansel; Arisoy, Sema; Burcu Akkus, Zeynep, Current Topics in Medicinal Chemistry, 2017

Abstract: Drug delivery to the brain is an engaged research topic in the field of nanomedicine. The passage of therapeutics into the brain parenchyma is more complicated than other body tissues due to it is limited by restrict barrier structure called blood-brain barrier (BBB). ...

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Current HPLC Methods for Assay of Nano Drug Delivery Systems

19-Apr-2017 | Evrim Kepekci Tekkeli, Serife; Volkan Kiziltas, Mustafa, Current Topics in Medicinal Chemistry, 2017

Abstract: In nano drug formulations the mechanism of release is a critical process to recognize controlled and targeted drug delivery systems. In order to gain high bioavailability and specificity from the drug to reach its therapeutic goal, the active substance must be loaded into the ...

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Nanofibers: New Insights for Drug Delivery and Tissue Engineering

19-Apr-2017 | Karim Haidar, Mohammad; Eroglu, Hakan, Current Topics in Medicinal Chemistry, 2017

Abstract: Nanofibers became one of the major research areas for drug delivery and tissue engineering applications in the last decade. Depending on the simplicity of the preparation method and high drug loading capacity, nanofibers provide many advantages for therapeutic perspectives. In ...

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Chemical Structure and Surface Modification of Dendritic Nanomaterials Tailored for Therapeutic and Diagnostic Applications

19-Apr-2017 | Hye Myung, Ja; Hsu, Hao-jui; Bugno, Jason; A. Tam, Kevin; Hong, Seungpyo, Current Topics in Medicinal Chemistry, 2017

Abstract: Dendritic nanomaterials have attracted a great deal of scientific interest due to their high capacity for multifunctionalization and potential in various biomedical applications, such as drug/gene delivery and diagnostic systems. Depending on the molecular structure and starting ...

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Amphiphilic Cyclodextrin Derivatives for Targeted Drug Delivery to Tumors

19-Apr-2017 | Erdogar, Nazlı; Varan, Gamze; Bilensoy, Erem, Current Topics in Medicinal Chemistry, 2017

Abstract: Villiers has extensively studied cyclodextrins, a family of macrocyclic oligosaccharides linked by α-1,4 glycosidic bonds, in different fields since their discovery in 1891. The unique structure enabling inclusion complexation for natural cyclodextrins and cyclodextrin derivatives make ...

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Template Synthesis of Tubular Nanostructures for Loading Biologically Active Molecules

19-Apr-2017 | Karatas, Aysegul; Hilal Algan, Aslıhan, Current Topics in Medicinal Chemistry, 2017

Abstract: The template synthesis is a low cost, simple and versatile nanofabrication method to produce cylindrical/tubular nanostructures with controllable dimensions such as length, diameter and aspect ratio. This method utilizes nanoporous membranes such as anodized aluminum oxide (AAO) ...

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Webinar | Translational applications in exosome research: From biomarker discovery to drug delivery

14-Apr-2017 | Elena V. Batrakova; Richard Jones; Anne Lynn S. Chang, Science , 2017

Exosomes—small, membrane-derived extracellular vesicles capable of carrying diverse biological cargo including proteins and microRNAs—have been found in a broad range of biological fluids and appear to be predominantly involved in cell-to-cell communication. Their natural characteristics make ...

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IJMS, Vol. 18, Pages 815: Prevention of Oxidized Low Density Lipoprotein-Induced Endothelial Cell Injury by DA-PLGA-PEG-cRGD Nanoparticles Combined with Ultrasound

13-Apr-2017 | Li, Zhaojun ; Huang, Hui ; Huang, Lili ; Du, Lianfang ; Sun, Ying ; Duan, Yourong, International Journal of Molecular Sciences, 2017

In general, atherosclerosis is considered to be a form of chronic inflammation. Dexamethasone has anti-inflammatory effects in atherosclerosis, but it was not considered for long-term administration on account of a poor pharmacokinetic profile and adverse side effects. Nanoparticles in which ...

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IJMS, Vol. 18, Pages 813: Novel Nano-Therapeutic Approach Actively Targets Human Ovarian Cancer Stem Cells after Xenograft into Nude Mice

12-Apr-2017 | Abou-ElNaga, Amoura ; Mutawa, Ghada ; El-Sherbiny, Ibrahim M.; Abd-ElGhaffar, Hassan ; Allam, Ahmed A.; Ajarem, Jama ..., International Journal of Molecular Sciences, 2017

The power of tumorigenesis, chemo-resistance and metastasis in malignant ovarian tumors resides in a tiny population of cancer cells known as ovarian cancer stem cells (OCSCs). Developing nano-therapeutic targeting of OCSCs is considered a great challenge. The potential use of ...

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Hierarchically Targeted and Penetrated Delivery of Drugs to Tumors by Size‐Changeable Graphene Quantum Dot Nanoaircrafts for Photolytic Therapy

11-Apr-2017 | Yu‐Lin Su, Ting‐Wei Yu, Wen‐Hsuan Chiang, Hsin‐Cheng Chiu, Chun‐Hsiang Chang, Chi‐Shiun Chiang, Shang‐Hsiu Hu, Advanced Functional Materials, 2017

Theranostic nanohybrids are promising for effective delivery of therapeutic drug or energy and for imaging‐guided therapy of tumors, which is demanded in personalized medicine. Here, a size‐changeable graphene quantum dot (GQD) nanoaircraft (SCNA) that serves as a hierarchical tumor‐targeting ...

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