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3,460 Newest Publications about the topic drug delivery

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Lipoic Acid Based Core Cross-linked Micelles for Multivalent Platform: Design, Synthesis and Application in Bio-imaging and Drug Delivery

24-May-2017 | Jingsheng Huang; Fang Wu; Yunlong Yu; Haolong Huang; Shiyong Zhang; Jingsong You, Organic & Biomolecular Chemistry, 2017

Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water. The presence of numerous disulfides accumulated in the core makes the micelles readily be cross-linked to achieve the establishment of core cross-linked micelles (CCMs). Thanks to the inherent ...

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A versatile microfluidic device for high throughput production of microparticles and cell microencapsulation

24-May-2017 | Samin Akbari; Tohid Pirbodaghi; Roger D. Kamm; Paula T. Hammond, Lab on a Chip, 2017

Biocompatible microparticles are valuable tools in biomedical research for applications such as drug delivery, cell transplantation therapy, and analytical assays. However, their translation into clinical research and the pharmaceutical industry has been slow due to the lack of techniques that ...

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Albumin‐Templated Manganese Dioxide Nanoparticles for Enhanced Radioisotope Therapy

19-May-2017 | Longlong Tian, Qian Chen, Xuan Yi, Jiawen Chen, Chao Liang, Yu Chao, Kai Yang, Zhuang Liu, Small, 2017

Although nanoparticle‐based drug delivery systems have been widely explored for tumor‐targeted delivery of radioisotope therapy (RIT), the hypoxia zones of tumors on one hand can hardly be reached by nanoparticles with relatively large sizes due to their limited intratumoral diffusion ability, ...

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IJMS, Vol. 18, Pages 1090: Synthesis and Characterization of Dual-Sensitive Fluorescent Nanogels for Enhancing Drug Delivery and Tracking Intracellular Drug Delivery

19-May-2017 | Wu, Szu-Yuan ; Debele, Tilahun Ayane; Kao, Yu-Chih ; Tsai, Hsieh-Chih, International Journal of Molecular Sciences, 2017

Here, dual-sensitive fluorescent branched alginate-polyethyleneimine copolymer (bAPSC) nanogels were synthesized from thiolated alginate and stearoyl-derivatized branched polyethyleneimine. The formation of bAPSC conjugates was confirmed through proton nuclear magnetic resonance and Fourier ...

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Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation

19-May-2017 | Mario M. Alvarez; Joanna Aizenberg; Mostafa Analoui; Anne M. Andrews; Gili Bisker; Edward S. Boyden; Roger D. Kamm; ..., ACS Nano, 2017

We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor ...

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Light-responsive molecular containers

18-May-2017 | Alejandro Díaz-Moscoso; Pablo Ballester, Chemical Communication, 2017

Encapsulation of small molecules in molecular containers able to release them in a controlled way in order to perform specific tasks (e.g. catalysis or drug delivery) constitutes an idea that has been around for several years. Light is becoming a perfect external stimulus to control the behaviour ...

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IJMS, Vol. 18, Pages 1079: [18F]-Fluorinated Carboplatin and [111In]-Liposome for Image-Guided Drug Delivery

18-May-2017 | Lamichhane, Narottam ; Dewkar, Gajanan K.; Sundaresan, Gobalakrishnan ; Mahon, Rebecca N.; Zweit, Jamal, International Journal of Molecular Sciences, 2017

Radiolabeled liposomes have been employed as diagnostic tools to monitor in vivo distribution of liposomes in real-time, which helps in optimizing the therapeutic efficacy of the liposomal drug delivery. This work utilizes the platform of [111In]-Liposome as a drug delivery vehicle, encapsulating ...

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Silica-encapsulated gold nanoparticle dimers for organelle-targeted cellular delivery

17-May-2017 | Vu Thanh Cong; Nguyễn Hoàng Ly; Sang Jun Son; Junhong Min; Sang-Woo Joo, Chemical Communication, 2017

Silica-encapsulated gold nanoparticle dimers were self-assembled through a single-insertion process using capillary force and can be utilized as an advanced drug-delivery and sensing platform for organelle-targeting in cancer cells.

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On‐demand Antimicrobial Treatment with Antibiotic‐Loaded Porous Silicon Capped with a pH‐Responsive Dual Plasma Polymer Barrier

16-May-2017 | Roshan Bharath Vasani, Endre J Szili, Gayathri Rajeev, Nicolas Hans Voelcker, Chemistry - An Asian Journal, 2017

Chronic wounds are a major socio‐economic problem. Bacterial infections in such wounds are a major contributor to lack of wound healing. An early indicator of wound infection is an increase in pH of the wound fluid. Herein, we describe the development of a pH‐responsive drug delivery device that ...

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pH‐Triggered Pinpointed Cascading Charge‐Conversion and Redox‐Controlled Gene Release Design: Modularized Fabrication for Nonviral Gene Transfection

16-May-2017 | Qian Jiang, Yu Nie, Xiaobing Chen, Yiyan He, Dong Yue, Zhongwei Gu, Advanced Functional Materials, 2017

Although pH and reduction responses are widely applied on gene and drug delivery system, the undefined molecule and disconnected response to corresponding transfection barriers still hamper their further application. Here, a multistage‐responsive lipopeptides polycation‐DNA nanoparticles (namely ...

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