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2,059 Newest Publications about the topic drug delivery

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Enhanced transdermal lymphatic drug delivery of hyaluronic acid modified transfersomes for tumor metastasis therapy

06-Jan-2015 | Ming Kong; Lin Hou; Juan Wang; Chao Feng; Ya Liu; Xiaojie Cheng; Xiguang Chen, Chemical Communication, 2015

A novel hyaluronic acid modified transfersome was prepared to deliver drugs to lymphatics through the transdermal route. Doxorubicin loaded HA-GMS-T was able to efficiently penetrate into the deep skin tissue, leading to enhanced absorption by lymphatics. Most importantly, hyaluronic acid ...

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Dual stimuli-responsive multi-drug delivery system for the individually controlled release of anti-cancer drugs

06-Jan-2015 | Wang Xiao; Xuan Zeng; Hang Lin; Kai Han; Hui-Zhen Jia; Xian-Zheng Zhang, Chemical Communication, 2015

A dual stimuli-responsive multi-drug delivery system was developed for “cancer cocktail therapy”. Upon UV irradiation, microcapsules could rapidly release the small-molecule drugs, and thereafter the macromolecular drugs would be released in the presence of MMP in the tumor cells. This system ...

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High electric conductivity of liquid crystals formed by ordered self-assembly of nonionic surfactant N,N-bis(2-hydroxyethyl)dodecanamide in water

06-Jan-2015 | Yan Zhang; Dechun Li; Pin Ya Li; Sen Zhang; Meng Wang; Ying Li, Soft Matter, 2015

This paper reported the ordered self-assembly of nonconductive small molecules achieved extra high conductivity, thereby stated an convenient approach constructing biofriendly soft material being suitable used as implantable biosensors and electro-stimulated drug delivery systems. The ...

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pH‐Responsive Capsules Engineered from Metal–Phenolic Networks for Anticancer Drug Delivery

03-Jan-2015 | Yuan Ping, Junling Guo, Hirotaka Ejima, Xi Chen, Joseph J. Richardson, Huanli Sun, Frank Caruso, Small, 2015

A new class of pH‐responsive capsules based on metal–phenolic networks (MPNs) for anticancer drug loading, delivery and release is reported. The fabrication of drug‐loaded MPN capsules, which is based on the formation of coordination complexes between natural polyphenols and metal ions over a ...

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Hybrid Materials: Theranostic USPIO‐Loaded Microbubbles for Mediating and Monitoring Blood‐Brain Barrier Permeation (Adv. Funct. Mater. 1/2015)

02-Jan-2015 | Twan Lammers, Patrick Koczera, Stanley Fokong, Felix Gremse, Josef Ehling, Michael Vogt, Andrij Pich, Gert Storm, Ma ..., Advanced Functional Materials, 2015

Enabling safe and efficient drug delivery across the blood‐brain barrier (BBB) remains to be challenging. On page 36 of this issue, T. Lammers, P. Koczera, F. Kiessling, and colleagues show that polymer‐based microbubbles, containing iron oxide nanoparticles within their shell, can be employed ...

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Cell membrane wrapping of a spherical thin elastic shell

31-Dec-2014 | Xin Yi; Huajian Gao, Soft Matter, 2014

Nanocapsules that can be tailored intelligently and specifically have drawn considerable attention in the fields of drug delivery and bioimaging. Here we conduct a theoretical study on cell uptake of a spherical nanocapsule which is modeled as a linear elastic solid thin shell in three ...

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Regulating Exocytosis of Nanoparticles via Host-Guest Chemistry

30-Dec-2014 | Chaekyu Kim; Gulen Tonga; Bo Yan; Chang Soo Kim; Sung Tae Kim; Myoung-Hwan Park; Zhengjiang Zhu; Bradley Duncan; Bri ..., Organic & Biomolecular Chemistry, 2014

Prolonged retention of internalized nanoparticulate systems inside cells improves their efficacy in imaging, drug delivery, and theranostic applications. Especially, regulating exocytosis of the nanoparticles is a key factor in the fabrication of effective nanocarriers for chemotherapeutic ...

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Mesoporous silica–chondroitin sulphate hybrid nanoparticles for targeted and bio-responsive drug delivery

30-Dec-2014 | Krishna Radhakrishnan; Jasaswini Tripathy; Akshay Datey; Dipshikha Chakravortty; Ashok M. Raichur, New Journal of Chemistry, 2014

This work proposes the fabrication of a novel targeted drug delivery system based on mesoporous silica-biopolymer hybrids that can release drugs in response to biological stimuli present in cancer cells. The proposed system utilizes mesoporous silica nanoparticles as a carrier to host the drug ...

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Poly[(maleic anhydride)-alt-(vinyl acetate)]: A Pure Oxygenic Nonconjugated Macromolecule with Strong Light Emission and Solvatochromic Effect

29-Dec-2014 | Engui Zhao; Jacky W. Y. Lam; Luming Meng; Yuning Hong; Haiqin Deng; Gongxun Bai; Xuhui Huang; Jianhua Hao; Ben Zhong ..., Macromolecules, 2014

Organic luminescent materials carrying no phenyl rings have attracted much interest from researchers due to their excellent biocompatibility and good biodegradability, which make them available for potential applications in a variety of biomedical areas, such as fluorescent bioprobe, drug ...

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Materials, Vol. 8, Pages 96-116: Adsorption of C.I. Natural Red 4 onto Spongin Skeleton of Marine Demosponge

29-Dec-2014 | Norman, Małgorzata ; Bartczak, Przemysław ; Zdarta, Jakub ; Tylus, Włodzimierz ; Szatkowski, Tomasz ; Stelling, Alli ..., Materials, 2014

C.I. Natural Red 4 dye, also known as carmine or cochineal, was adsorbed onto the surface of spongin-based fibrous skeleton of Hippospongia communis marine demosponge for the first time. The influence of the initial concentration of dye, the contact time, and the pH of the solution on the ...

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