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3,635 Newest Publications about the topic drug delivery


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DNA Tetrahedron Nanostructures for Biological Applications: Biosensors and Drug Delivery

15-Aug-2017 | Nuli Xie; Shiyuan Liu; Xiaohai Yang; Xiaoxiao He; Jin Huang; Kemin Wang, Analyst, 2017

With the rapid development of DNA nanotechnology, various DNA nanostructures with different shapes and sizes have been self-assembled using “bottom-up” fabrication strategies, and applied in a wide range of fields, such as biosensors, drug delivery and tools for molecular biology. As a classical ...


Hydrolyzed collagen‐grafted‐poly[(acrylic acid)‐co‐(methacrylic acid)] hydrogel for drug delivery

12-Aug-2017 | Supaporn Noppakundilograt, Sopinya Choopromkaw, Suda Kiatkamjornwong, Journal of Applied Polymer Science, 2017

ABSTRACT Hydrolyzed collagen‐grafted‐poly[(acrylic acid)‐co‐(methacrylic acid)] hydrogels were synthesized by solution polymerization and confirmed by infrared spectroscopy. From sequential univariate analysis, the optimal molar ratio of acrylic acid: methacrylic acid was 92:8 in the presence ...


Logic‐Gate Functions in Chemomechanical Materials

11-Aug-2017 | Hans‐Jörg Schneider, ChemPhysChem, 2017

Abstract Chemomechanical polymers that change their shape or volume on stimulation by multiple external chemical signals, particularly on the basis of selective molecular recognition, are discussed. Several examples illustrate how such materials, usually in the form of hydrogels, can be used ...


6‐Mercaptopurine‐Induced Fluorescence Quenching of Monolayer MoS2 Nanodots: Applications to Glutathione Sensing, Cellular Imaging, and Glutathione‐Stimulated Drug Delivery

11-Aug-2017 | Shih‐Chiang Chen, Chang‐Yu Lin, Tian‐Lu Cheng, Wei‐Lung Tseng, Advanced Functional Materials, 2017

Molybdenum disulfide (MoS2) nanodots (NDs) with sulfur vacancies have been demonstrated to be suitable to conjugate thiolated molecules. However, thiol‐induced fluorescence quenching of MoS2 NDs has been rarely explored. In this study, 6‐mercaptopurine (6‐MP) serves as an efficient quencher for ...


Binary Mixtures of Sodium Salt of Ibuprofen and Selected Bile Salts: Interface, Micellar, Thermodynamic, and Spectroscopic Study

11-Aug-2017 | Malik Abdul Rub; Naved Azum; Abdullah M. Asiri, Journal of Chemical & Engineering Data, 2017

With the intention to explore bile salts applications as drug delivery vehicles, the mixed interfacial as well as micellar behavior of the sodium salt of ibuprofen (NaIbuF) and bile salts mixtures in aqueous/electrolyte solutions has been evaluated by tensiometric method at 298.15 K. Bile salts ...


The Current State of Peptide Drug Discovery: Back to the Future?

11-Aug-2017 | Antoine Henninot; James C. Collins; John M. Nuss, Journal of Medicinal Chemistry, 2017

Over the past decade, peptide drug discovery has experienced a revival of interest and scientific momentum, as the pharmaceutical industry has come to appreciate the role that peptide therapeutics can play in addressing unmet medical needs and how this class of compounds can be an excellent ...


Amphiphilic Peptide Nanorods Based on Oligo-Phenylalanine as a Biocompatible Drug Carrier

11-Aug-2017 | Su Jeong Song; Seulgi Lee; Kyoung-Seok Ryu; Joon Sig Choi, Bioconjugate Chemistry, 2017

Peptide nanostructure has been widely explored for drug-delivery systems in recent studies. Peptides possess comparatively lower cytotoxicity and are more efficient than polymeric carriers. Here, we propose a peptide nanorod system, composed of an amphiphilic oligo-peptide RH3F8 (Arg–His3–Phe8), ...


Dual-Targeted Cascade-Responsive Prodrug Micelle System for Tumor Therapy in Vivo

11-Aug-2017 | Liangliang Dai; Ruisi Cai; Menghuan Li; Zhong Luo; Yonglin Yu; Weizhen Chen; Xinkun Shen; Yuxia Pei; Xiaojing Zhao; ..., Chemistry of Materials, 2017

This study reports a cascade-responsive disassemble micellar drug delivery system with dual-targeting potential (cell and mitochondria targeting), which optimizes the distribution of antitumor drugs on systemic, local, and subcellular levels to enhance antitumor efficacy. A new cationic porphyrin ...


Self‐assembled amphiphilic poly‐N‐vinylpyrrolidone nanoparticles as carriers for hydrophobic drugs: Stability aspects

10-Aug-2017 | Andrey N. Kuskov, Pavel P. Kulikov, Anastasia V. Goryachaya, Manolis N. Tzatzarakis, Aristidis M. Tsatsakis, Kelly V ..., Journal of Applied Polymer Science, 2017

ABSTRACT Nanoparticles can experience numerous impacts during storage or after intravenous administration resulting in disassembly and/or drug leakage and affecting their efficiency as drug delivery systems. In this study, this crucial issue was addressed by investigating the stability of ...


Materials, Vol. 10, Pages 929: Smart Carriers and Nanohealers: A Nanomedical Insight on Natural Polymers

10-Aug-2017 | Raveendran, Sreejith ; Rochani, Ankit K.; Maekawa, Toru ; Kumar, D. Sakthi, Materials, 2017

Materials, Vol. 10, Pages 929: Smart Carriers and Nanohealers: A Nanomedical Insight on Natural Polymers Materials doi: 10.3390/ma10080929 Authors: Sreejith Raveendran Ankit Rochani Toru Maekawa D. Kumar Biodegradable polymers are popularly being used in an increasing number ...


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