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11,675 Newest Publications about the topic expression


Regulation of IGFBP-2 expression during fasting

01-May-2015 | Kang HS; Kim M-Y; Kim S-J; Lee J-H; Kim Y-D; Seo Y-K; Bae J-H; Oh G-T; Song D-K; Ahn Y-H; Im S-S, Biochemical Journal, 2015

Insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2), one of the most abundant circulating IGFBPs, is known to attenuate the biological action of IGF-1. Although the effect of IGFBP-2 in preventing metabolic disorders is well known, its regulatory mechanism remains unclear. In the present ...


Exploiting the Brønsted Acidity of Phosphinecarboxamides for the Synthesis of New Phosphides and Phosphines

17-Apr-2015 | Andrew R. Jupp, Gemma Trott, Éléonore Payen de la Garanderie, James D. G. Holl, Duncan Carmichael, Jose M. Goicoechea, Chemistry - A European Journal, 2015

Abstract We demonstrate that the synthesis of new N‐functionalized phosphinecarboxamides is possible by reaction of primary and secondary amines with PCO− in the presence of a proton source. These reactions proceed with varying degrees of success, and although primary amines generally afford ...


Transcript Dynamics at Early Stages of Molecular Interactions of MYMIV with Resistant and Susceptible Genotypes of the Leguminous Host, Vigna mungo

17-Apr-2015 | Anirban Kundu et al., PLoS ONE, 2015

by Anirban Kundu, Anju Patel, Sujay Paul, Amita Pal Initial phases of the MYMIV- Vigna mungo interaction is crucial in determining the infection phenotype upon challenging with the virus. During incompatible interaction, the plant deploys multiple stratagems that include extensive ...


Comparative Transcriptomic Analysis Reveals Similarities and Dissimilarities in Saccharomyces cerevisiae Wine Strains Response to Nitrogen Availability

17-Apr-2015 | Catarina Barbosa et al., PLoS ONE, 2015

by Catarina Barbosa, José García-Martínez, José E. Pérez-Ortín, Ana Mendes-Ferreira Nitrogen levels in grape-juices are of major importance in winemaking ensuring adequate yeast growth and fermentation performance. Here we used a comparative transcriptome analysis to uncover wine yeasts ...


Rapamycin and Chloroquine: The In Vitro and In Vivo Effects of Autophagy-Modifying Drugs Show Promising Results in Valosin Containing Protein Multisystem Proteinopathy

17-Apr-2015 | Angèle Nalbandian et al., PLoS ONE, 2015

by Angèle Nalbandian, Katrina J. Llewellyn, Christopher Nguyen, Puya G. Yazdi, Virginia E. Kimonis Mutations in the valosin containing protein (VCP) gene cause hereditary Inclusion body myopathy (hIBM) associated with Paget disease of bone (PDB), frontotemporal dementia (FTD), more recently ...


Anti‐Inflammatory Activities of Rubus Fruit Anthocyanins in Inflamed Human Intestinal Epithelial Cells

17-Apr-2015 | Hana Jung, Hee Jae Lee, Hyunnho Cho, Keum Taek Hwang, Journal of Food Biochemistry, 2015

Abstract The purpose of this study was to investigate anti‐inflammatory activities of anthocyanin fractions (AF) from blackberries (BB), Korean raspberries (KR) and black raspberries (BR) and their major anthocyanins (cyanidin‐3‐glucoside [C3G] and cyanidin‐3‐rutinoside [C3R]) in inflamed ...


ChemInform Abstract: New Flavonol Methyl Ether from the Leaves of Vitex peduncularis Exhibits Potential Inhibitory Activity Against Leishmania donovani Through Activation of iNOS Expression.

16-Apr-2015 | Prasenjit Rudrapaul, Indrajit Sil Sarma, Niranjan Das, Utpal Chandra De, Surajit Bhattacharjee, Biswanath Dinda, ChemInform, 2015

Abstract New flavonol methyl ether, vitecetin (I), is isolated together with four known compounds from the leaves of Vitex peduncularis.


Neuroprotective effects of Argon are mediated via an ERK‐1/2 dependent regulation of heme‐oxygenase‐1 in retinal ganglion cells

16-Apr-2015 | Felix Ulbrich, Kai B. Kaufmann, Mark Coburn, Wolf Alexander Lagrèze, Martin Roesslein, Julia Biermann, Hartmut Buerk ..., Journal of Neurochemistry, 2015

Abstract Retinal ischemia and reperfusion injuries (R‐IRI) damage neuronal tissue permanently. Recently, we demonstrated that Argon exerts anti‐apoptotic and protective properties. The molecular mechanism remains unclear. We hypothesized that Argon inhalation exert neuroprotective effects in ...


Label-Free Quartz Crystal Microbalance with Dissipation Monitoring of Resveratrol Effect on Mechanical Changes and Folate Receptor Expression Levels of Living MCF-7 Cells: A Model for Screening of Drugs

16-Apr-2015 | Shaolian Zhang; Haihua Bai; Jiang Pi; Peihui Yang; Jiye Cai, Analytical Chemistry, 2015

Quartz crystal microbalance with dissipation (QCM-D) monitoring was used for real-time and label-free detection of changes and folate receptor (FR) expression levels on living MCF-7 cells for evaluating the anticancer activity of resveratrol. Here, the mechanical changes of cellular responses to ...


Molecules, Vol. 20, Pages 6888-6900: Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid

16-Apr-2015 | Lee, Ji Young; Park, Wansu, Molecules, 2015

Wogonin (5,7-dihydroxy-8-methoxyflavone) is an active flavonoid compound originally isolated from Scutellaria radix, which has been used to treat lung inflammation in Korea, China, and Japan. Wogonin has been known to inhibit inducible nitric oxide synthase and have the anti-tumor properties. ...


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