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Correction and removal of expression of concern: A unifying mechanism for the rearrangement of vinyl allene oxide geometric isomers to cyclopentenones

24-Mar-2017 | Richard Kelly, Organic & Biomolecular Chemistry, 2017

Correction and removal of expression of concern for ‘A unifying mechanism for the rearrangement of vinyl allene oxide geometric isomers to cyclopentenones’ by Adán B. González-Pérez et al., Org. Biomol. Chem., 2014, 12, 7694–7701.


Surface plasmon resonance (SPR) imaging for ABH antigens detection of RBCs and saliva: secretor status-related ABO subgroup identification

24-Mar-2017 | Patjaree Peungthum; Krisda Sudprasert; Ratthasart Amarit; Armote Somboonkaew; Boonsong Sutapun; Apirom Vongsakulyano ..., Analyst, 2017

Low antigenic expression of subgroup ABO blood system on red blood cell (RBC) is cause of discrepancy between forward and reverse blood typing in standard agglutination technique. Neutralization agglutination for detection of ABH substance in saliva is employed for verification. However, ...


Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells

19-Mar-2017 | Author(s): Seoung Rak Lee, Seulah Lee, Eunjung Moon, Hye-Jin Park, Hyun Bong Park, Ki Hyun Kim, Bioorganic Chemistry, 2017

Publication date: February 2017 Source:Bioorganic Chemistry, Volume 70 Author(s): Seoung Rak Lee, Seulah Lee, Eunjung Moon, Hye-Jin Park, Hyun Bong Park, Ki Hyun Kim Poria cocos Wolf (Polyporaceae) has been used as a medicinal fungus to treat various diseases since ancient ...


Molecules, Vol. 22, Pages 486: Ginsenoside PPD’s Antitumor Effect via Down-Regulation of mTOR Revealed by Super-Resolution Imaging

19-Mar-2017 | Teng, Bo ; Jiang, Junguang ; Zhao, Lijing ; Gao, Jing ; Chen, Junyu ; Liu, Zhe ; Wang, Hongda ; Lu, Binfeng, Molecules, 2017

Derived from Panax ginseng, the natural product 20(S)-Protopanaxadiol (PPD) has been reported for its cytotoxicity against several cancer cell lines. The molecular mechanism is, however, not well understood. Here we show that PPD significantly inhibits proliferation, induces apoptosis and causes ...


IJMS, Vol. 18, Pages 663: Brain-Derived Neurotrophic Factor Loaded PS80 PBCA Nanocarrier for In Vitro Neural Differentiation of Mouse Induced Pluripotent Stem Cells

19-Mar-2017 | Chung, Chiu-Yen ; Lin, Martin Hsiu-Chu; Lee, I-Neng ; Lee, Tsong-Hai ; Lee, Ming-Hsueh ; Yang, Jen-Tsung, International Journal of Molecular Sciences, 2017

Brain derived neurotrophic factor (BDNF) can induce neural differentiation in stem cells and has the potential for repair of the nervous system. In this study, a polysorbate 80-coated polybutylcyanoacrylate nanocarrier (PS80 PBCA NC) was constructed to deliver plasmid DNAs (pDNAs) containing BDNF ...


Tumor Suppressor PTPRJ Is a Target of miR‐155 in Colorectal Cancer

18-Mar-2017 | Xiao‐Fei Zhang, Rongfu Tu, Keke Li, Pengxiang Ye, Xiaofeng Cui, Journal of Cellular Biochemistry, 2017

Abstract PTPRJ is known for its antiproliferative role. Loss of heterozygosity (LOH) of PTPRJ has frequently been observed in various human cancers including colorectal cancer (CRC), lung cancer and breast cancer. However, the function and mechanism of PTPRJ in CRC is not well understood. At ...


IJMS, Vol. 18, Pages 661: Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

18-Mar-2017 | Eadon, Michael T.; Hause, Ronald J.; Stark, Amy L.; Cheng, Ying-Hua ; Wheeler, Heather E.; Burgess, Kimberly S.; Ben ..., International Journal of Molecular Sciences, 2017

Colistin sulfate (polymixin E) is an antibiotic prescribed with increasing frequency for severe Gram-negative bacterial infections. As nephrotoxicity is a common side effect, the discovery of pharmacogenomic markers associated with toxicity would benefit the utility of this drug. Our objective ...


Residual impact of methyl salicylate fumigation at the breaker stage on C6 volatile biopathway in red tomato fruit

17-Mar-2017 | Libin Wang, Xuehui Li, Jinhe Bai, Haibo Luo, Changhai Jin, Jie Hui, Zhifang Yu, Journal of Food Processing and Preservation, 2017

Abstract Fatty acid derived C6 volatiles, including cis−3‐hexenal, hexanal, trans−2‐hexenal, and cis−3‐hexenol, are important contributors to tomato aroma. Methyl salicylate (MeSA), a critical mobile signal, functions in tomato ripening as well as (a)biotic stress; however, information is ...


Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in Vanishing White Matter Disease

17-Mar-2017 | Gali Raini, Reut Sharet, Melisa Herrero, Andrea Atzmon, Anjana Shenoy, Tamar Geiger, Orna Elroy‐Stein, Journal of Neurochemistry, 2017

Abstract Eukaryotic translation initiation factor 2B (eIF2B) is a master regulator of protein synthesis under normal and stress conditions. Mutations in any of the five genes encoding its subunits lead to Vanishing White Matter (VWM) disease, a recessive genetic deadly illness caused by ...


Reprogramming of histone methylation controls the differentiation of monocytes into macrophages

17-Mar-2017 | Qi‐Fan Zheng, Hui‐Min Wang, Zhan‐Feng Wang, Jin‐Yang Liu, Qi Zhang, Li Zhang, Yuan‐Hua Lu, Han You, Guang‐Hui Jin, FEBS Journal, 2017

Abstract Subset heterogeneity of the mononuclear phagocyte system (MPS) is controlled by defined transcriptional networks and programs; however, the dynamic establishment of programs that control broad, orchestrated expression of transcription factors (TFs) during the progression of ...


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