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14,954 Newest Publications about the topic expression


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Dehydrogenation of ethane to ethylene via radical pathways enhanced by alkali metal based catalyst in oxysteam condition

21-Aug-2016 | Kazuhiro Takanabe, Salman Shahid, AIChE Journal, 2016

The dehydrogenation of ethane to ethylene in the presence of oxygen and water was conducted using Na2WO4/SiO2 catalyst at high temperatures. At 923 K, the conversion rate without water was proportional to ethane pressure and a half order of oxygen pressure, consistent with a kinetically relevant ...


The expression levels of cellular prion protein affect copper isotopic shifts in the organs of mice

20-Aug-2016 | Kerri A. Miller; Catherine M. Keenan; Gary R. Martin; Frank R. Jirik; Keith A. Sharkey; Michael E. Wieser, Journal of Analytical Atomic Spectrometry, 2016

The metabolic processes involving copper, such as cellular assimilation, electron transfer and protein formation, can partition copper isotopes in the body amongst different organs and bodily fluids. Systematic changes in copper isotopic composition in the body may assist in identifying regions ...


From adsorption to condensation: the role of adsorbed molecular clusters

19-Aug-2016 | Sima Yaghoubian; Seyed Hadi Zandavi; C. A. Ward, Physical Chemistry Chemical Physics, 2016

The adsorption of heptane vapour on a smooth silicon substrate with a lower temperature than the vapour is examined analytically and experimentally. An expression for the amount adsorbed under steady state conditions is derived from the molecular cluster model of the adsorbate that is similar to ...


Fludioxonil induced the cancer growth and metastasis via altering epithelial–mesenchymal transition via an estrogen receptor‐dependent pathway in cellular and xenografted breast cancer models

19-Aug-2016 | Ryeo‐Eun Go, Cho‐Won Kim, So‐Ye Jeon, Yong‐Sub Byun, Eui‐Bae Jeung, Ki‐Hoan Nam, Kyung‐Chul Choi, Environmental Toxicology, 2016

ABSTRACT Fludioxonil is an antifungal agent used in agricultural applications that is present at measurable amounts in fruits and vegetables. In this study, the effects of fludioxonil on cancer cell viability, epithelial–mesenchymal transition (EMT), and metastasis were examined in MCF‐7 ...


Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus

19-Aug-2016 | Ming‐Wei Chao, Chin‐Hua Yang, Po‐Ting Lin, Yu‐Hsiu Yang, Yu‐Chen Chuang, Meng‐Chi Chung, Chia‐Yi Tseng, Environmental Toxicology, 2016

ABSTRACT PM2.5 travels along the respiratory tract and enters systemic blood circulation. Studies have shown that PM2.5 increases the incidence of various diseases not only in adults but also in newborn infants. It causes chronic inflammation in pregnant women and retards fetal development. In ...


Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain

18-Aug-2016 | Divyaanka Iyer, Supriya V. Vartak, Archita Mishra, Gunaseelan Goldsmith, Sujeet Kumar, Mrinal Srivastava, Mahesh Heg ..., FEBS Journal, 2016

The antiapoptotic protein BCL2 is overexpressed in several cancers and contributes to prolonged cell survival and chemoresistance, lending itself as an excellent target for cancer therapy. Here, we report the design, synthesis, and characterization of Disarib, a novel BCL2 inhibitor. Disarib ...


Exposure to an environmentally relevant mixture of organochlorine compounds and polychlorinated biphenyls Promotes hepatic steatosis in male Ob/Ob mice

17-Aug-2016 | Charlee Mulligan, Sandeep Kondakala, Eun‐Ju Yang, John V. Stokes, James A. Stewart, Barbara L. F. Kaplan, George E. ..., Environmental Toxicology, 2016

ABSTRACT Hepatic steatosis is recognized as an independent risk factor for the development of cardiovascular disease. While obesity and type 2 diabetes are well‐established risk factors in the development of hepatic steatosis, recent studies have revealed exposure to mixtures of persistent ...


Delivery of Small Genetic Molecules through Hollow Porous Nanoparticles Silences Target Gene and in Turn Stimulates Osteoblastic Differentiation

16-Aug-2016 | Jung‐Ju Kim, Rajendra K. Singh, Kapil D. Patel, Hae‐Won Kim, Particle & Particle Systems Characterization, 2016

Nanocarriers are one of the key elements to improve the therapeutic potential of signaling molecules, including genes for the disease treatment and tissue repair. Here, a nanocarrier system is reported that delivers genetic molecule small interference RNA (siRNA) for osteoblastic stimulation. ...


Heterologous Regulation of the Cannabinoid Type 1 Receptor by Angiotensin II in Astrocytes of Spontaneously Hypertensive Rats

16-Aug-2016 | Dhanush Haspula, Michelle A. Clark, Journal of Neurochemistry, 2016

Abstract Brainstem and cerebellar astrocytes have critical roles to play in hypertension and attention deficit hyperactivity disorder (ADHD), respectively. Angiotensin (Ang) II, via the astroglial Ang Type 1 receptor (AT1R), has been demonstrated to elevate pro‐inflammatory mediators in the ...


Mechanism of Different Stereoisomeric Astaxanthin in Resistance to Oxidative Stress in Caenorhabditis elegans

16-Aug-2016 | Xiaojuan Liu, Qingxin Luo, Yong Cao, Timothy Goulette, Xin Liu, Hang Xiao, Journal of Food Science, 2016

Abstract As a potent antioxidant in human diet, astaxanthin (AST) may play important roles in alleviating oxidative stress‐driven adverse physiological effects. This study examined the effects of different stereoisomers of AST in protecting Caenorhabditis elegans from chemically induced ...


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