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12,243 Newest Publications about the topic expression

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A Review: G-Quadruplex’s Applications in Biological Target Detection and Drug Delivery

07-Jul-2015 | Tian, Tian; Xiao, Heng; Zhou, Xiang, Current Topics in Medicinal Chemistry, 2015

Abstract: The G-quadruplex is one of the most important DNA secondary structures and has elicited widespread interest in this field of scientific research. As Gquadruplex studies have progressed, its significant roles in a variety of biological process have been revealed, including ...

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Approximate analytical solution for non-linear reaction diffusion equations in a mono-enzymatic biosensor involving Michaelis–Menten kinetics

05-Jul-2015 | Author(s): O.M. Kirthiga , L. Rajendran, Journal of Electroanalytical Chemistry, 2015

Publication date: 15 August 2015 Source:Journal of Electroanalytical Chemistry, Volume 751 Author(s): O.M. Kirthiga , L. Rajendran Here we consider the case where the enzyme reacts with an electroinactive substrate to produce an electroactive product which is quickly oxidized or reduced ...

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Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives

05-Jul-2015 | Author(s): Ivana Pibiri , Laura Lentini , Raffaella Melfi , Giulia Gallucci , Andrea Pace , Angelo Spinello , ..., European Journal of Medicinal Chemistry, 2015

Publication date: 28 August 2015 Source:European Journal of Medicinal Chemistry, Volume 101 Author(s): Ivana Pibiri , Laura Lentini , Raffaella Melfi , Giulia Gallucci , Andrea Pace , Angelo Spinello , Giampaolo Barone , Aldo Di Leonardo Premature stop codons are the result of ...

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Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8‐deficient mice

04-Jul-2015 | K.E. Bosse, J.L. Charlton, L.L. Susick, B. Newman, A.L. Eagle, T.A. Mathews, S.A. Perrine, A.C. Conti, Journal of Neurochemistry, 2015

Abstract The cAMP/protein kinase A pathway regulates methamphetamine (METH)‐induced neuroplasticity underlying behavioral sensitization. We hypothesize that adenylyl cyclases (AC) 1/8 mediate these neuroplastic events and associated striatal dopamine regulation. Locomotor responses to METH (1 ...

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Prenatal Exposure to Bisphenol A Disrupts Mouse Fetal Liver Maturation in a Sex‐Specific Manner

04-Jul-2015 | Bianca DeBenedictis, Haiyan Guan, Kaiping Yang, Journal of Cellular Biochemistry, 2015

ABSTRACT Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals in the environment. Developmental exposure to BPA is known to be associated with liver dysfunction and diseases, such as hepatic steatosis, liver tumors, metabolic syndrome, and altered hepatic gene ...

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Issue Cover (July 2015)

03-Jul-2015 | Journal of Neurochemistry, 2015

Front cover: Representative photomicrographs of the midbrain (RN overview) in high magnification. AAV‐mediated EGFP‐expression (green) delineates the transduced area. Immunolabeling for NeuN (red), DAPI (blue). Scale bars 1000 micrometer. Read the full article ‘AAV‐mediated expression of ...

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Modulation of cytokines and chemokines expression by NAC in cadmium chloride treated human lung cells

03-Jul-2015 | Caroline O. Odewumi, Lekan M. Latinwo, Michael L. Ruden, Veera L. D. Badisa, Sheila Fils‐Aime, Ramesh B. Badisa, Environmental Toxicology, 2015

ABSTRACT Cadmium (Cd), is one of the most hazardous metals found in the environment. Cd exposure through inhalation has been linked to various diseases in lungs. It was shown that Cd induces proinflammatory cytokines through oxidative stress mechanism. In this report, we studied the ...

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Ultra‐structural hair alterations in Friedreich's ataxia: A scanning electron microscopic investigation

03-Jul-2015 | F. Pinar Turkmenoglu, U. Baran Kasirga, H. Hamdi Celik, Microscopy Research and Technique, 2015

ABSTRACT Friedreich's ataxia (FRDA) is an autosomal recessive inherited disorder involving progressive damage to the central and peripheral nervous systems and cardiomyopathy. FRDA is caused by the silencing of the FXN gene and reduced levels of the encoded protein, frataxin. Frataxin is a ...

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Structural activity relationship analysis (SAR) and in vitro testing reveal the anti‐aging potential activity of Acetyl Aspartic Acid

03-Jul-2015 | J.M. Gillbro, M. Lundahl, M. Westman, R. Baral, T. Al‐Bader, A. Mavon, International Journal of Cosmetic Science, 2015

Abstract Background Acetyl aspartic acid (A‐A‐A) was discovered through gene array analysis with corresponding connectivity mapping (Cmap), aiming for identification of new compounds with anti‐ageing properties. Objective The aim of this study was to use structural activity ...

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IJMS, Vol. 16, Pages 15104-15117: BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9

03-Jul-2015 | Chou, Chou-Kit ; Wu, Chang-Yi ; Chen, Jeff Yi-Fu; Ng, Ming-Chong ; Wang, Hui-Min David; Chen, Jen-Hao ; Yuan, Shyng- ..., International Journal of Molecular Sciences, 2015

BubR1 is a critical component of spindle assembly checkpoint, ensuring proper chromatin segregation during mitosis. Recent studies showed that BubR1 was overexpressed in many cancer cells, including oral squamous cell carcinomas (OSCC). However, the effect of BubR1 on metastasis of OSCC remains ...

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