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11,537 Newest Publications about the topic expression


Targeting Kruppel-Like Factor 5 (KLF5) for Cancer Therapy

26-Mar-2015 | Gao, Yu; Ding, Ye; Chen, Haiying; Chen, Haijun; Zhou, Jia, Current Topics in Medicinal Chemistry, 2015

Abstract: Kruppel-like factor 5 (KLF5) belongs to a family of zinc-finger-containing transcription factors which are involved in regulating expression of a wide range of genes, thereby affecting diverse cellular functions. The activities of KLF5 are regulated by multiple signaling pathways ...


Development of PET Probes for Cancer Imaging

24-Mar-2015 | Huang, Rui; Wang, Mingwei; Zhu, Yizhou; S. Conti, Peter; Chen, Kai, Current Topics in Medicinal Chemistry, 2015

Abstract: Positron emission tomography (PET) is one of the most rapidly growing areas of medical imaging for cancer research. The principal goal of PET imaging is to visualize, characterize, and measure biological processes at the molecular and cellular levels in living subjects using ...


Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit Gram-positive bacteria growth by regulating metabolism and virulence genes expression

22-Mar-2015 | Author(s): Lirong Huang , Heng Luo , Qiji Li , Daoping Wang , Jianxin Zhang , Xiaojiang Hao , Xiaosheng Yang, European Journal of Medicinal Chemistry, 2015

Publication date: 5 May 2015 Source:European Journal of Medicinal Chemistry, Volume 95 Author(s): Lirong Huang , Heng Luo , Qiji Li , Daoping Wang , Jianxin Zhang , Xiaojiang Hao , Xiaosheng Yang The hydroxyl group in ring A of pentacyclic triterpene is essential for antibacterial ...


Flavonoid metabolites reduce tumor necrosis factor‐α secretion to a greater extent than their precursor compounds in human THP‐1 monocytes

20-Mar-2015 | Jessica L. di Gesso, Jason S. Kerr, Qingzhi Zhang, K. Saki Raheem, S. Krishna Yalamanchili, David O'Hagan, Colin D. ..., Molecular Nutrition & Food Research, 2015

Scope : Flavonoids are generally studied in vitro, in isolation, and as unmetabolised precursor structures. However, in the habitual diet, multiple flavonoids are consumed together and found present in the circulation as complex mixtures of metabolites. Using a unique study design we ...


Comparison of different methods to estimate the uncertainty in composition measurement by chromatography

20-Mar-2015 | Adriana Alexandra Aparicio Ariza, Elizabeth Ayala Blanco, Luis Eduardo García Sánchez, Carlos Eduardo García Sánchez, Journal of Separation Science, 2015

Natural gas is a mixture that contains hydrocarbons and other compounds, such as CO2 and N2. Natural gas composition is commonly measured by gas chromatography, and this measurement is important for the calculation of some thermodynamic properties that determine its commercial value. The ...


Structure Determination of Feline Calicivirus Virus-Like Particles in the Context of a Pseudo-Octahedral Arrangement

20-Mar-2015 | Wim P. Burmeister et al., PLoS ONE, 2015

by Wim P. Burmeister, Marlyse Buisson, Leandro F. Estrozi, Guy Schoehn, Olivier Billet, Zahia Hannas, Cécile Sigoillot, Hervé Poulet The vesivirus feline calicivirus (FCV) is a positive strand RNA virus encapsidated by an icosahedral T=3 shell formed by the viral VP1 protein. Upon its ...


Overexpression of Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) Correlates with Cell Aggressiveness and Poor Survival in Gastric Cancer

20-Mar-2015 | Qing-Bin Meng et al., PLoS ONE, 2015

by Qing-Bin Meng, Wei-Ming Kang, Jian-Chun Yu, Yu-Qin Liu, Zhi-Qiang Ma, Li Zhou, Quan-Cai Cui, Wei-Xun Zhou Eukaryotic translation initiation factor 5A2 (EIF5A2) plays an important role in tumor progression and prognosis evaluation. However, little information is available about its potential ...


High ABCC2 and Low ABCG2 Gene Expression Are Early Events in the Colorectal Adenoma-Carcinoma Sequence

20-Mar-2015 | Vibeke Andersen et al., PLoS ONE, 2015

by Vibeke Andersen, Lotte K Vogel, Tine Iskov Kopp, Mona Sæbø, Annika W. Nonboe, Julian Hamfjord, Elin H. Kure, Ulla Vogel Development of colorectal cancer (CRC) may result from a dysfunctional interplay between diet, gut microbes and the immune system. The ABC transport proteins ABCB1 ...


Aberrant Expression of PHLPP1 and PHLPP2 Correlates with Poor Prognosis in Patients with Hypopharyngeal Squamous Cell Carcinoma

20-Mar-2015 | Jieyu Zhou et al., PLoS ONE, 2015

by Jieyu Zhou, Xuemin Yu, Juan Wang, Tao Li, Tong Jin, Dapeng Lei, Xinliang Pan The PHLPP (pleckstrin homology [PH] domain leucine rich repeat protein phosphatase) family, which represents a family of novel Ser/Thr protein phosphatases, is composed of 2 members: PHLPP1 and PHLPP2. PHLPPs ...


Time-Dependent Effect of Hypoxia on Tumor Progression and Liver Progenitor Cell Markers in Primary Liver Tumors

20-Mar-2015 | Eliene Bogaerts et al., PLoS ONE, 2015

by Eliene Bogaerts, Femke Heindryckx, Lindsey Devisscher, Annelies Paridaens, Yves-Paul Vandewynckel, Anja Van den Bussche, Xavier Verhelst, Louis Libbrecht, Leo A. van Grunsven, Anja Geerts, Hans Van Vlierberghe Background & Aims Expression of liver progenitor cell (LPC) characteristics has ...


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