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Mechanisms of Fatal Cardiotoxicity following High-Dose Cyclophosphamide Therapy and a Method for Its Prevention

26-Jun-2015 | Takuro Nishikawa et al., PLoS ONE, 2015

by Takuro Nishikawa, Emiko Miyahara, Koichiro Kurauchi, Erika Watanabe, Kazuro Ikawa, Kousuke Asaba, Takayuki Tanabe, Yasuhiro Okamoto, Yoshifumi Kawano Observed only after administration of high doses, cardiotoxicity is the dose-limiting effect of cyclophosphamide (CY). We investigated the ...


Disposition of Astragaloside IV via Enterohepatic Circulation Is Affected by the Activity of the Intestinal Microbiome

22-Jun-2015 | Yi Jin; Xingjie Guo; Bo Yuan; Wenhong Yu; Hao Suo; Zhiyuan Li; Haiyan Xu, Journal of Agricultural and Food Chemistry, 2015

Astragaloside IV (ASIV) is a typical bioactive constituent of Radix Astragali. The study aimed to investigate the enterohepatic circulation of ASIV and evaluate the impact of activity of intestinal microbiota on the deposition of ASIV. The amounts of ASIV and its metabolites were quantified by an ...


Energies, Vol. 8, Pages 6033-6058: Energy Crop-Based Biogas as Vehicle Fuel—The Impact of Crop Selection on Energy Efficiency and Greenhouse Gas Performance

18-Jun-2015 | Börjesson, Pål ; Prade, Thomas ; Lantz, Mikael ; Björnsson, Lovisa, Energies, 2015

The production of biogas from six agricultural crops was analysed regarding energy efficiency and greenhouse gas (GHG) performance for vehicle fuel from a field-to-tank perspective, with focus on critical parameters and on calculation methods. The energy efficiency varied from 35% to 44%, ...


Hydroalumination of Ketenimines and Subsequent Reactions with Heterocumulenes: Synthesis of Unsaturated Amide Derivatives and 1,3-Diimines

02-Jun-2015 | Xing Jin; Matthias Willeke; Ralph Lucchesi; Constantin-Gabriel Daniliuc; Roland Fröhlich; Birgit Wibbeling; Werner U ..., The Journal of Organic Chemistry, 2015

The series of differently substituted ketenimines 1 was hydroluminated using di-iso-butyl aluminum hydride. For the sterically congested ketenimine 1a, preferred hydroalumination of the C═N-bond was proven by X-ray crystallography (compound 5a). In situ treatment of the hydroaluminated ...


Manganese peroxidase and biomimetic systems applied to in vitro lignin degradation in Eucalyptus grandis milled wood and kraft pulps

01-Jun-2015 | Fernando Masarin, Marcela Norambuena, Heloisa O.R. Ramires, Braz J. Demuner, Paulo C. Pavan, André Ferraz, Journal of Chemical Technology & Biotechnology, 2015

Abstract Background Organoperoxyl radicals generated from unsaturated fatty acids can initiate lignin degradation reactions. Results Manganese peroxidase (MnP, EC produced by the basidiomycete Ceriporiopsis subvermispora and biomimetic systems were explored to produce ...


IJERPH, Vol. 12, Pages 5886-5904: Assessment of Electromagnetic Interference with Active Cardiovascular Implantable Electronic Devices (CIEDs) Caused by the Qi A13 Design Wireless Charging Board

27-May-2015 | Seckler, Tobias ; Jagielski, Kai ; Stunder, Dominik, International Journal of Environmental Research and Public Health, 2015

Electromagnetic interference is a concern for people wearing cardiovascular implantable electronic devices (CIEDs). The aim of this study was to assess the electromagnetic compatibility between CIEDs and the magnetic field of a common wireless charging technology. To do so the voltage induced in ...


Synergistic Effects of [Ile7]Surfactin Homologues with Bacillomycin D in Suppression of Gray Mold Disease by Bacillus amyloliquefaciens Biocontrol Strain SD-32

27-May-2015 | Keijitsu Tanaka; Yusuke Amaki; Atsushi Ishihara; Hiromitsu Nakajima, Journal of Agricultural and Food Chemistry, 2015

We previously reported that Bacillus amyloliquefaciens biocontrol strain SD-32 produces powerful antifungal lipopeptides, C17 bacillomycin D homologues. In the course of the investigation we found that the antifungal activity of the culture supernatant of this bacterium was not ascribed ...


Dioxomolybdenum(VI) chelates of bioinorganic, catalytic, and medicinal relevance: Studies on some cis-dioxomolybdenum(VI) complexes involving O, N-donor 4-oximino-2-pyrazoline-5-one derivatives

24-May-2015 | Author(s): R.C. Maurya , J. Chourasia , M.H. Martin , S. Roy , A.K. Sharma , P. Vishwakarma, Arabian Journal of Chemistry, 2015

Publication date: May 2015 Source:Arabian Journal of Chemistry, Volume 8, Issue 3 Author(s): R.C. Maurya , J. Chourasia , M.H. Martin , S. Roy , A.K. Sharma , P. Vishwakarma A new series of five mixed-ligand complexes of dioxomolybdenum(VI) of the general composition [MoO2(L)2(H2O)2], ...


The origin, measurement and control of fine particles in non‐aqueous hydraulic fluids and their effect on fluid and system performance

23-May-2015 | W. D. Phillips, J. W. G. Staniewski, Tribotest, 2015

Abstract When assessing the cleanliness of industrial hydraulic fluids, current procedures focus on particles above 4 µm in size. However, the use of more sophisticated techniques has confirmed that substantial numbers of much smaller particles can be formed in use — mainly by high‐temperature ...


Sources of organic matter in Changjiang (Yangtze River) bed sediments: preliminary insights from organic geochemical proxies

17-May-2015 | Author(s): Zhongqiao Li , Francien Peterse , Ying Wu , Hongyan Bao , Timothy I. Eglinton , Jing Zhang, Organic Geochemistry, 2015

Publication date: Available online 11 May 2015 Source:Organic Geochemistry Author(s): Zhongqiao Li , Francien Peterse , Ying Wu , Hongyan Bao , Timothy I. Eglinton , Jing Zhang Insight into the content and composition of organic carbon (OC) in river systems contributes to our ...


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