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990 Newest Publications about the topic medicinal chemistry
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Coumarin chalcone fibrates: A new structural class of lipid lowering agents
13-05-2013 | Author(s): Koneni V. Sashidhara , Gopala Reddy Palnati , Ravi Sonkar , Srinivasa Rao Avula , Chetan Awasthi , G ..., European Journal of Medicinal Chemistry, 2013
Publication date: June 2013 Source:European Journal of Medicinal Chemistry, Volume 64 Author(s): Koneni V. Sashidhara , Gopala Reddy Palnati , Ravi Sonkar , Srinivasa Rao Avula , Chetan Awasthi , Gitika Bhatia In our continuing search for safe and efficacious antidyslipidemic ...
3-Biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and analogues, novel Flaviviridae inhibitors
13-05-2013 | Author(s): Cécile Enguehard-Gueiffier , Simone Musiu , Nicolas Henry , Jean-Baptiste Véron , Sylvie Mavel , Joh ..., European Journal of Medicinal Chemistry, 2013
Publication date: June 2013 Source:European Journal of Medicinal Chemistry, Volume 64 Author(s): Cécile Enguehard-Gueiffier , Simone Musiu , Nicolas Henry , Jean-Baptiste Véron , Sylvie Mavel , Johan Neyts , Pieter Leyssen , Jan Paeshuyse , Alain Gueiffier Using Ttou 84 as ...
Synthesis and preliminary in vitro biological evaluation of 7α-testosterone–chlorambucil hybrid designed for the treatment of prostate cancer
13-05-2013 | Author(s): Dominic Bastien , Rana Hanna , Valérie Leblanc , Éric Asselin , Gervais Bérubé, European Journal of Medicinal Chemistry, 2013
Publication date: June 2013 Source:European Journal of Medicinal Chemistry, Volume 64 Author(s): Dominic Bastien , Rana Hanna , Valérie Leblanc , Éric Asselin , Gervais Bérubé The synthesis of 7α-testosterone–chlorambucil hybrid is reported. This compound is made from testosterone ...
Synthesis of novel 1-[5-(4-methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-piperazine derivatives and evaluation of their in vivo anticonvulsant activity
13-05-2013 | Author(s): Kikkeri P. Harish , Kikkeri N. Mohana , Lingappa Mallesha , Basavapatna N. Prasanna kumar, European Journal of Medicinal Chemistry, 2013
Publication date: Available online 11 May 2013 Source:European Journal of Medicinal Chemistry Author(s): Kikkeri P. Harish , Kikkeri N. Mohana , Lingappa Mallesha , Basavapatna N. Prasanna kumar A series of novel 1-[5-(4-methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-piperazine derivatives ...
Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility
13-05-2013 | Stephen S. Scully; Alicia J. Tang; Morten Lundh; Carrie M. Mosher; Kedar M. Perkins; Bridget K. Wagner, Journal of Medicinal Chemistry, 2013
Journal of Medicinal Chemistry DOI: 10.1021/jm400397x
Sustainable Practices in Medicinal Chemistry: Current State and Future Directions
09-05-2013 | Marian C. Bryan; Barry Dillon; Lawrence G. Hamann; Gregory J. Hughes; Michael E. Kopach; Emily A. Peterson; Mehrnaz ..., Journal of Medicinal Chemistry, 2013
Journal of Medicinal Chemistry DOI: 10.1021/jm400250p
Correction to Systematic in Vivo Screening of a Series of 1-Propyl-4-arylpiperidines against Dopaminergic and Serotonergic Properties in Rat Brain: A Scaffold-Jumping Approach
08-05-2013 | Cecilia Mattsson; Theresa Andreasson; Nicholas Waters; Clas Sonesson, Journal of Medicinal Chemistry, 2013
Journal of Medicinal Chemistry DOI: 10.1021/jm400509x
Artificial Neural Networks for Efficient Clustering of Conformational Ensembles and their Potential for Medicinal Chemistry
08-05-2013 | Pandini, Alessandro; Fraccalvieri, Domenico; Bonati, Laura, Current Topics in Medicinal Chemistry, 2013
Abstract: The biological function of proteins is strictly related to their molecular flexibility and dynamics: enzymatic activity, protein-protein interactions, ligand binding and allosteric regulation are important mechanisms involving protein motions. Computational approaches, such ...
Ontologies in Medicinal Chemistry: Current Status and Future Challenges
08-05-2013 | Gomez-Perez, Asuncion; Martinez-Romero, Marcos; Rodriguez-Gonzalez, Alejandro; Vazquez, Guillermo; Vazquez-Naya, Jose M., Current Topics in Medicinal Chemistry, 2013
Abstract: Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, synthesis and biological evaluation of compounds. However, with this ...
MIANN Models in Medicinal, Physical and Organic Chemistry
08-05-2013 | Gonzalez-Diaz, Humberto; Arrasate, Sonia; Sotomayor, Nuria; Lete, Esther; R Munteanu, Cristian; Pazos, Alejandro; Be ..., Current Topics in Medicinal Chemistry, 2013
Abstract: Reducing costs in terms of time, animal sacrifice, and material resources with computational methods has become a promising goal in Medicinal, Biological, Physical and Organic Chemistry. There are many computational techniques that can be used in this sense. In any case, ...
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