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3,335 Newest Publications about the topic microscopes


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Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy

01-Feb-2016 | Holger Stark; Ashwin Chari, Journal of Electron Microscopy, 2016

Single particle cryo-EM has recently developed into a powerful tool to determine the 3D structure of macromolecular complexes at near-atomic resolution, which allows structural biologists to build atomic models of proteins. All technical aspects of cryo-EM technology have been considerably ...


Unclonable Plasmonic Security Labels Achieved by Shadow‐Mask‐Lithography‐Assisted Self‐Assembly

29-Jan-2016 | Yuanhui Zheng, Cheng Jiang, Soon Hock Ng, Yong Lu, Fei Han, Udo Bach, J. Justin Gooding, Advanced Materials, 2016

An unclonable plasmonic anti‐counterfeiting strategy is demonstrated, which involves the use of molecule‐embedded metal@silica core–shell nanoparticles as information carriers. A shadow‐mask‐lithography‐assisted self‐assembly is developed for the fabrication of the plasmonic security labels. ...


A MEMS‐based heating holder for the direct imaging of simultaneous in‐situ heating and biasing experiments in scanning/transmission electron microscopes

28-Jan-2016 | Luigi Mele, Stan Konings, Pleun Dona, Francis Evertz, Christoph Mitterbauer, Pybe Faber, Ruud Schampers, Joerg R. Ji ..., Microscopy Research and Technique, 2016

ABSTRACT The introduction of scanning/transmission electron microscopes (S/TEM) with sub‐Angstrom resolution as well as fast and sensitive detection solutions support direct observation of dynamic phenomena in‐situ at the atomic scale. Thereby, in‐situ specimen holders play a crucial role: ...


Backscattered electron SEM imaging of resin sections from plant specimens: observation of histological to subcellular structure and CLEM

28-Dec-2015 | N.W. RIZZO, K.E. DUNCAN, T.M. BOURETT, R.J. HOWARD, Journal of Microscopy, 2015

Summary We have refined methods for biological specimen preparation and low‐voltage backscattered electron imaging in the scanning electron microscope that allow for observation at continuous magnifications of ca. 130–70 000 X, and documentation of tissue and subcellular ultrastructure detail. ...


Sensors, Vol. 15, Pages 31566-31580: Multidirectional Image Sensing for Microscopy Based on a Rotatable Robot

15-Dec-2015 | Shen, Yajing ; Wan, Wenfeng ; Zhang, Lijun ; Yong, Li ; Lu, Haojian ; Ding, Weili, Sensors, 2015

Image sensing at a small scale is essentially important in many fields, including microsample observation, defect inspection, material characterization and so on. However, nowadays, multi-directional micro object imaging is still very challenging due to the limited field of view (FOV) of ...


Contrasting confocal with defocusing microscale spatially offset Raman spectroscopy

11-Dec-2015 | C. Conti, M. Realini, C. Colombo, A. Botteon, P. Matousek, Journal of Raman Spectroscopy, 2015

The study compares and contrasts conventional confocal Raman microscopy/spectroscopy (CRM) with a recently developed micrometer scale defocusing spatially offset Raman spectroscopy (micro‐SORS), a method providing a new analytical capability for investigating non‐destructively the chemical ...


Intraoperative Spectroscopy with Ultrahigh Sensitivity for Image-Guided Surgery of Malignant Brain Tumors

07-Dec-2015 | Brad A. Kairdolf; Alexandros Bouras; Milota Kaluzova; Abhinav K. Sharma; May Dongmei Wang; Constantinos G. Hadjipana ..., Analytical Chemistry, 2015

Intraoperative cancer imaging and fluorescence-guided surgery have attracted considerable interest because fluorescence signals can provide real-time guidance to assist a surgeon in differentiating cancerous and normal tissues. Recent advances have led to the clinical use of a natural fluorophore ...


Zirconia coatings deposited by novel plasma‐enhanced aerosol–gel method

03-Dec-2015 | Sebastian Miszczak, Bożena Pietrzyk, Daniel Kucharski, physica status solidi (a), 2015

The sol–gel technique is well known and widely used for manufacturing coatings. An aerosol–gel method is a modification of the classic sol–gel process. Preparation of coatings by this technique involves the formation of an aerosol and its deposition on the coated surfaces, where the aerosol ...


[In Depth] Second bid for brain observatory

23-Oct-2015 | Emily Underwood, Science , 2015

Last Friday, prior to the Society for Neuroscience annual meeting in nearby Chicgao, nearly 100 top researchers and government officials met to discuss a bold proposal: the creation of a National Brain Observatory, a network of neurotechnology centers tied to the Department of Energy's (DOE's) ...


Cell imaging: Beyond the limits

22-Oct-2015 | Katherine Bourzac, Nature, 2015

Cell imaging: Beyond the limits Nature. doi:10.1038/526S50a Author: Katherine Bourzac Powerful super-resolution microscopes that allow researchers to explore the world at the nanoscale are set to transform our understanding of the ...


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