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8,171 Newest Publications about the topic molecular weight

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Synthesis of phenanthiridine spiropyrans and studies of their effects on G-quadruplex DNA

24-Mar-2017 | Madeleine Livendahl; Jan Jamroskovic; Mattias Hedenstrom; Tim Görlich; Nasim Sabouri; Erik Chorell, Organic & Biomolecular Chemistry, 2017

G-quadruplex (G4) DNA structures are involved in many important biological processses and can be linked to several human diseases. Drug-like low molecular weight compounds that target G4 structures are therefore interesting for their potential therapeutic properties but also for their potential ...

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Dependence of Hydration Status of Bacterial Light-Harvesting Complex 2 on Polyol Cosolvents

24-Mar-2017 | Ying Shi; Jie Yu; Long-Jiang Yu; Peng Wang; Li-Min Fu; Jian-Ping Zhang; Zheng-Yu Wang-Otomo, Photochemical & Photobiological Sciences, 2017

Low molecular weight (MW) polyols are organic as osmolytes influencing protein structure and activity. We have intended to investigate the effects of low MW polyols on the optical and excited-state properties of the light-harvesting complex 2 (LH2) isolated from photosynthetic bacterium ...

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A Novel Method for Preparation of Linezolid, (S)-N-((3-(3-Fluoro-4- Morpholinophenyl)-2-Oxo-5-Oxazolidinyl) Methyl) Acetamide

21-Mar-2017 | Seku, Kondaiah; Badathala, Vijayakumar; Srinivasa Rao Velivela, Venkata; Reddy Desireddy, Srinivasa, Letters in Organic Chemistry, 2017

Abstract: Background: Linezolid (I) [(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl) methyl) acetamide] is a synthetic antibiotic used for the treatment of serious infections caused by grampositive bacteria that are resistant to other antibiotics. Linezolid empirical formula ...

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Synergy modification of the microstructure and the property of PBO fiber by γ‐ray radiation

17-Mar-2017 | Chunhua Zhang, Chenyang Zhang, Qi Zhang, Dawei Jiang, Fubin Yu, Yan Liang, Polymer Engineering and Science, 2017

The effects of γ‐ray radiation on PBO fibers and its composite materials have been investigated, the results showed that the microstructure and the performance of radiated PBO fibers have been improved with 30–120 kGy radiation dose, cross‐linking reactions came from PBO polymer molecule chains ...

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Functional polyisobutylenes via electrophilic cleavage/alkylation

17-Mar-2017 | C. Garrett Campbell, Robson F. Storey, Journal of Polymer Science Part A: Polymer Chemistry, 2017

ABSTRACT Lewis‐acid catalyzed degradation of poly(isobutylene‐co‐isoprene) (butyl rubber) in the presence of an alkoxybenzene compound was studied as a new route toward low molecular weight multifunctional polyisobutylenes. Simultaneous cleavage and functionalization of butyl rubber was ...

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Effect of drying methods on physicochemical properties and in vitro hypoglycemic effects of orange peel dietary fiber

16-Mar-2017 | Yanlong Liu, Chuanhui Fan, Ming Tian, Ziyu Yang, Fengxia Liu, Siyi Pan, Journal of Food Processing and Preservation, 2017

Abstract Dietary fiber plays an important role in the prevention and reduction of chronic diseases. This study evaluated the effect of drying methods (hot air drying, vacuum drying, and freeze‐drying) on physicochemical properties and in vitro hypoglycemic effects of soluble and insoluble ...

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The observation of PP/EVA blends in which isotactic PP was preradiated with different radiation absorbed doses

16-Mar-2017 | Yicheng Zhang, Jianxi Li, Liguo Shen, Hongjun Lin, Yongdong Shan, Journal of Applied Polymer Science, 2017

ABSTRACT Isotactic polypropylene (PP) was preradiated by γ ray with different absorbed doses and subsequently blended with ethylene‐vinyl acetate co‐polymer (EVA) to prepare PP/EVA blends. The average molecular weight (Mn) of isotactic PP decreased with the increasing of radiation absorbed ...

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Stereocomplex Crystallization of Linear Two-Armed Stereo Diblock Copolymers: Effects of Chain Directional Change, Coinitiator Moiety, and Terminal Groups

16-Mar-2017 | Hideto Tsuji; Michiaki Ogawa; Yuki Arakawa, The Journal of Physical Chemistry B, 2017

Two-armed poly(l-lactide) (PLLA)-b-poly(d-lactide) (PDLA) (2-LD) copolymers with a wide-range of molecular weight were synthesized and the effect of coinitiator moiety, which functions as impurity and causes chain directional change in the middle of molecules (Effect A), and/or the additional ...

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Toward Understanding the Cold, Hot, and Neutral Nature of Chinese Medicines Using in Silico Mode-of-Action Analysis

16-Mar-2017 | Xianjun Fu; Lewis H. Mervin; Xuebo Li; Huayun Yu; Jiaoyang Li; Siti Zuraidah Mohamad Zobir; Azedine Zoufir; Yang Zho ..., Journal of Chemical Information and Modeling, 2017

One important, however, poorly understood, concept of Traditional Chinese Medicine (TCM) is that of hot, cold, and neutral nature of its bioactive principles. To advance the field, in this study, we analyzed compound–nature pairs from TCM on a large scale (>23 000 structures) via chemical space ...

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Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks

15-Mar-2017 | Volkan Yesilyurt, Andrew M. Ayoob, Eric A. Appel, Jeffrey T. Borenstein, Robert Langer, Daniel G. Anderson, Advanced Materials, 2017

Hydrogels play a central role in a number of medical applications and new research aims to engineer their mechanical properties to improve their capacity to mimic the functional dynamics of native tissues. This study shows hierarchical mechanical tuning of hydrogel networks by utilizing mixtures ...

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