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6,119 Newest Publications about the topic molecular weight

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Linifanib – A Multi-Targeted Receptor Tyrosine Kinase Inhibitor and a Low Molecular Weight Gelator

05-Mar-2015 | Maria Marlow; Simon Wheeler; Michael J Stocks; Mohammed Al-Ameedee; Thomas Smith, Chemical Communication, 2015

In this study we demonstrate that linifanib, a multi-targeted receptor tyrosine kinase inhibitor, with a key urea containing pharmacophore, self-assembles into a hydrogel in the presence of low amounts of solvent. We demonstrate the role of the urea functional group and that of fluorine ...

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IDB-containing low molecular weight short peptide as efficient DNA cleavage reagent

04-Mar-2015 | Chunying Ma; Huan Chen; Chao Li; Jin Zhang; Renzhong Qiao, Organic & Biomolecular Chemistry, 2015

Artificial nucleases have attracted significant interest due to their abilities in accelerating DNA cleavage, which makes the possibility of genome manipulation. However, compared with natural nucleases, currently available artificial nucleases have low cleavage efficiency, especially those ...

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Stochastic methods for aerosol chemistry: a compact molecular description of functionalization and fragmentation in the heterogeneous oxidation of squalane aerosol by OH radicals

01-Mar-2015 | A. A. Wiegel; K. R. Wilson; W. D. Hinsberg; F. A. Houle, Physical Chemistry Chemical Physics, 2015

The heterogeneous oxidation of organic aerosol by hydroxyl radicals (OH) can proceed through two general pathways: functionalization, in which oxygen functional groups are added to the carbon skeleton, and fragmentation, in which carbon–carbon bonds are broken, producing higher volatility, lower ...

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Size and morphology controlling of PLGA microparticles produced by electro hydrodynamic atomization

28-Feb-2015 | Milad Jafari‐Nodoushan, Jalal Barzin, Hamid Mobedi, Polymers for Advanced Technologies, 2015

Among the various methods used to produce microparticles, electrospraying is becoming increasingly popular, and it has the advantage of control over the size, shape and morphology of the produced particles. Particle size and morphology are the main factors used to control the rate of microsphere ...

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Copolymerization of fluorene‐based main‐chain benzoxazine and their high performance thermosets

28-Feb-2015 | Tiantian Feng, Jun Wang, Hui Wang, Noureddine Ramdani, Liwu Zu, Wenbin Liu, Xiaodong Xu, Polymers for Advanced Technologies, 2015

A series of fluorene‐based benzoxazine copolymers were synthesized from the mixture of 9,9‐bis(4‐hydroxyphenyl)fluorene and bisphenol A, and 4,4′‐diaminodiphenyloxide and paraformaldehyde. And the cured polybenzoxazine films derived from these copolymers were also obtained. Fourier transform ...

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Suppressing the long‐chain branching in the synthesis of poly(styrene‐b‐butyl acrylate‐b‐styrene) in RAFT emulsion polymerization by tuning the interfacial properties

27-Feb-2015 | Yunlong Guo, Xiang Gao, Yingwu Luo, Journal of Polymer Science Part A: Polymer Chemistry, 2015

ABSTRACT Reversible addition‐fragmentation chain transfer (RAFT) emulsion polymerization is becoming an important technique to synthesize the latex of block copolymers. A previous study showed that in the synthesis of polystyrene‐b‐poly(butyl acrylate)‐b‐polystyrene triblock copolymer via RAFT ...

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Tuning salicylate‐based polymers to overcome lag time and extend release via copolymers and polymer blends

27-Feb-2015 | Leonid Garber, Neel Jingar, Roselin Rosario‐Meléndez, Kathryn E. Uhrich, Journal of Polymer Science Part B: Polymer Physics, 2015

ABSTRACT This work describes how physicochemical properties of salicylate‐based poly(anhydride‐esters) (PAEs) can be tuned for drug delivery and optimized by comparing copolymerization with polymer blending. These alterations reduced the lag time of drug release, while still maintaining a ...

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Low Molecular Weight Heparin (LMWH) Improves Peritoneal Function and Inhibits Peritoneal Fibrosis Possibly through Suppression of HIF-1α, VEGF and TGF-β1

27-Feb-2015 | Juan Li et al., PLoS ONE, 2015

by Juan Li, Zhi Yong Guo, Xian Hua Gao, Qi Bian, Meng Jia, Xue Li Lai, Tie Yun Wang, Xiao Lu Bian, Hai Yan Wang Background Peritoneal fibrosis is the major cause of ultrafiltration failure, and intraperitoneal administration of Low Molecular Weight Heparin (LMWH) was reported to protect ...

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Photochemical Transformation of Graphene Oxide in Sunlight

27-Feb-2015 | Wen-Che Hou; Indranil Chowdhury; David G. Goodwin, Jr.; W. Matthew Henderson; D. Howard Fairbrother; Dermont Bouchar ..., Environmental Science & Technology, 2015

Graphene oxide (GO) is promising in scalable production and has useful properties that include semiconducting behavior, catalytic reactivity, and aqueous dispersibility. In this study, we investigated the photochemical fate of GO under environmentally relevant sunlight conditions. The results ...

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Photoinduced Synthesis of α,ω-Telechelic Sequence-Controlled Multiblock Copolymers

27-Feb-2015 | Athina Anastasaki; Vasiliki Nikolaou; Nicholas William McCaul; Alexandre Simula; Jamie Godfrey; Christopher Waldron; ..., Macromolecules, 2015

Photoinduced living radical polymerization has been employed to synthesize α,ω-telechelic multiblock copolymers of a range of acrylic monomers including methyl acrylate (MA), ethyl acrylate (EA), ethylene glycol methyl ether acrylate (EGA), and solketal acrylate (SA). Under carefully optimized ...

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