29-04-2013 | Irene Díaz‐Moreno, José M. García‐Heredia, Katiuska González‐Arzola, Antonio Díaz‐Quintana, Miguel Á. De la Rosa, ChemPhysChem, 2013

Abstract Tyrosine nitration is a common post‐translational modification affecting protein structure and function. It is based on the addition of a NO2 group at the ortho position of the phenolic hydroxyl group of tyrosine to yield 3‐nitrotyrosine (3‐NTyr). Understanding how tyrosine ...

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24-04-2013 | Debabrata Maiti; Srimanta Manna; Sandipan Jana; Tapish Saboo; Arun Maji, Chemical Communication, 2013

Nitroolefins are usually synthesized using Henry reaction. Here we report an alternative metal-free decarboxylative nitration protocol for the preparation of the nitro-olefins from α,β- unsaturated carboxylic acids using t-butylnitrite (t-BuONO) and TEMPO. α ,β -Unsaturated carboxylic acids ...

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08-04-2013 | Daiber, Andreas ; Daub, Steffen ; Bachschmid, Markus ; Schildknecht, Stefan ; Oelze, Matthias ; Steven, Sebastian ; ..., International Journal of Molecular Sciences, 2013

The reaction product of nitric oxide and superoxide, peroxynitrite, is a potent biological oxidant. The most important oxidative protein modifications described for peroxynitrite are cysteine-thiol oxidation and tyrosine nitration. We have previously demonstrated that intrinsic heme-thiolate ...

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20-03-2013 | Jonathan Jacoway, G. G. K. S. Narayana Kumar, Kenneth K. Laali, ChemInform, 2013

Abstract A broad spectrum of activated arenes is investigated with the title method.

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19-03-2013 | Maria Clara Franco; Yaozu Ye; Christian A. Refakis; Jessica L. Feldman; Audrey L. Stokes; Manuela Basso; Raquel M. M ..., Proceedings of the National Academy of Sciences current issue, 2013

Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging. Tyrosine nitration in these conditions has been reported extensively, but whether tyrosine nitration is a marker or plays a role in the cell-death processes was unknown. ...

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01-03-2013 | Stefan Schildknecht, Hanne R. Gerding, Christiaan Karreman, Malte Drescher, Hilal A. Lashuel, Tiago F. Outeiro, Dona ..., Journal of Neurochemistry, 2013

Abstract Alpha synuclein (ASYN) is a major constituent of the typical protein aggregates observed in several neurodegenerative diseases that are collectively referred to as synucleinopathies. A causal involvement of ASYN in the initiation and progression of neurological diseases is ...

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22-02-2013 | Soham Maity; Srimanta Manna; Sujoy Rana; Togati Naveen; Arijit Mallick; Debabrata Maiti, Journal of the American Chemical Society, 2013

Journal of the American Chemical Society DOI: 10.1021/ja311942e

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30-01-2013 | Young-Hyuk Joo; Jin Hyuk Chung; Soo Gyeong Cho; Eun Mee Goh, New Journal of Chemistry, 2013

Eight new energetic salts based on 1-methoxy-5-nitroiminotetrazole, which was obtained by nitration of 1-methoxy-5-aminotetrazole, were synthesized. Guanidinium (5), aminoguanidinium (6), diaminoguanidinium (7), triaminoguanidinium (8), carbohydrazidinium (9), 3-amino-1,2,4-triazolium (10), ...

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09-01-2013 | Shuai Wang, Chun Chun Shu, Tao Wang, Jin Yu, Guo Bing Yan, ChemInform, 2013

Abstract The use of tert‐butyl nitrite under air offers an attractive alternative to traditional protocols.

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12-12-2012 | Masahiro Sadakane; Keisuke Sasaki; Hiroki Nakamura; Takashi Yamamoto; Wataru Ninomiya; Wataru Ueda, Langmuir, 2012

We demonstrate that the glass-transition temperature (Tg) of a polymer sphere template is a crucial factor in the production of three-dimensionally ordered macroporous (3DOM) materials. Metal nitrate dissolved in ethylene glycol–methanol was infiltrated into the void of a face-centered, ...

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