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Luminescent bioactive NHC-metal complexes to bring light into cells

24-Nov-2015 | Catherine Hemmert; Heinz GORNITZKA, Dalton Transactions, 2015

Organometallic complexes are mostly used in catalytic applications and nowadays biomedical applications reach more and more attention. Until the last decade, research in the later area was focused on screening of complexes against cancer cell lines, bacterials or parasites. Since a couple of ...


Latex co‐coagulation approach to fabrication of polyurethane/graphene nanocomposites with improved electrical conductivity, thermal conductivity, and barrier property

20-Nov-2015 | Sheng Li Wu, Tie Jun Shi, Li Yuan Zhang, Journal of Applied Polymer Science, 2015

ABSTRACT This study describes a simple and effective method of synthesis of a polyurethane/graphene nanocomposite. Cationic waterborne polyurethane (CWPU) was used as the polymer matrix, and graphene oxide (GO) as a starting nanofiller. The CWPU/GO nanocomposite was prepared by first mixing a ...


[Report] Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2

20-Nov-2015 | Alexander Jaworski; Irene Tom; Raymond K. Tong; Holly K. Gildea; Alexander W. Koch; Lino C. Gonzalez; Marc Tessier-L ..., Science , 2015

Axon pathfinding is orchestrated by numerous guidance cues, including Slits and their Robo receptors, but it remains unclear how information from multiple cues is integrated or filtered. Robo3, a Robo family member, allows commissural axons to reach and cross the spinal cord midline by ...


Accelerating electrostatic interaction calculations with graphical processing units based on new developments of ewald method using non‐uniform fast fourier transform

19-Nov-2015 | Sheng‐Chun Yang, Yong‐Lei Wang, Gui‐Sheng Jiao, Hu‐Jun Qian, Zhong‐Yuan Lu, Journal of Computational Chemistry, 2015

We present new algorithms to improve the performance of ENUF method (F. Hedman, A. Laaksonen, Chem. Phys. Lett. 425, 2006, 142) which is essentially Ewald summation using Non‐Uniform FFT (NFFT) technique. A NearDistance algorithm is developed to extensively reduce the neighbor list size in ...


Structural Optimization of Triboelectric Nanogenerator for Harvesting Water Wave Energy

19-Nov-2015 | Tao Jiang; Li Min Zhang; Xiangyu Chen; Chang Bao Han; Wei Tang; Chi Zhang; Liang Xu; Zhong Lin Wang, ACS Nano, 2015

Ocean waves are one of the most abundant energy sources on earth, but harvesting such energy is rather challenging due to various limitations of current technologies. Recently, networks formed by triboelectric nanogenerator (TENG) have been proposed as a promising technology for harvesting water ...


IJERPH, Vol. 12, Pages 14828-14841: Harm Reduction as “Continuum Care” in Alcohol Abuse Disorder

19-Nov-2015 | Maremmani, Icro ; Cibin, Mauro ; Pani, Pier Paolo; Rossi, Alessandro ; Turchetti, Giuseppe, International Journal of Environmental Research and Public Health, 2015

Alcohol abuse is one of the most important risk factors for health and is a major cause of death and morbidity. Despite this, only about one-tenth of individuals with alcohol abuse disorders receive therapeutic intervention and specific rehabilitation. Among the various dichotomies that limit an ...


High‐performance computational analysis and peptide screening from databases of cyclotides from poaceae

17-Nov-2015 | William Farias Porto, Vivian de Jesus Miranda, Michelle Flaviane Soares Pinto, Stephan Machado Dohms, Octavio Luiz F ..., Peptide Science, 2015

Abstract Cyclotides are a family of head‐to‐tail cyclized peptides containing three conserved disulfide bonds, in a structural scaffold also known as a cyclic cystine knot. Due to the high degree of cysteine conservation, novel members from this peptide family can be identified in protein ...


IJMS, Vol. 16, Pages 27391-27400: Cell-Penetrating Ability of Peptide Hormones: Key Role of Glycosaminoglycans Clustering

16-Nov-2015 | Tchoumi Neree, Armelle ; Nguyen, Phuong Trang; Bourgault, Steve, International Journal of Molecular Sciences, 2015

Over the last two decades, the potential usage of cell-penetrating peptides (CPPs) for the intracellular delivery of various molecules has prompted the identification of novel peptidic identities. However, cytotoxic effects and unpredicted immunological responses have often limited the use of ...


Sequential Change in Physicochemical Properties of LDL During Oxidative Modification

15-Nov-2015 | Author(s): Toshimi Kido, Kazuo Kondo, Hiroshige Itakura, Shinji Yokoyama, Chemistry and Physics of Lipids, 2015

Publication date: Available online 11 November 2015 Source:Chemistry and Physics of Lipids Author(s): Toshimi Kido, Kazuo Kondo, Hiroshige Itakura, Shinji Yokoyama Oxidized LDL is thought to be a highly atherogenic lipoprotein. Structural background of this pathogenesis, however, ...


[In Depth] Cancer research centers pool tumor genome data

13-Nov-2015 | Jocelyn Kaiser, Science , 2015

An international consortium of academic research centers is pooling data on patients' tumor genomes and their clinical outcomes to learn more about the role of cancer-causing mutations. The American Association for Cancer Research's Project GENIE, which stands for Genomics, Evidence, Neoplasia, ...


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