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Surgical models of Roux-en-Y gastric bypass surgery and sleeve gastrectomy in rats and mice

01-Mar-2015 | Bote G Bruinsma; Korkut Uygun; Martin L Yarmush; Nima Saeidi, Nature Protocols, 2015

Nature Protocols 10, 495 (2015). doi:10.1038/nprot.2015.027 Authors: Bote G Bruinsma, Korkut Uygun, Martin L Yarmush & Nima Saeidi Bariatric surgery is the only definitive solution currently available for the present obesity pandemic. These operations typically involve ...


Energies, Vol. 8, Pages 1505-1528: Energy Coordinative Optimization of Wind-Storage-Load Microgrids Based on Short-Term Prediction

16-Feb-2015 | Hu, Changbin ; Luo, Shanna ; Li, Zhengxi ; Wang, Xin ; Sun, Li, Energies, 2015

According to the topological structure of wind-storage-load complementation microgrids, this paper proposes a method for energy coordinative optimization which focuses on improvement of the economic benefits of microgrids in the prediction framework. First of all, the external characteristic ...


Catching the Missing Million: Experiences in Enhancing TB & DR-TB Detection by Providing Upfront Xpert MTB/RIF Testing for People Living with HIV in India

06-Feb-2015 | Neeraj Raizada et al., PLoS ONE, 2015

by Neeraj Raizada, Kuldeep Singh Sachdeva, Achuthan Sreenivas, Shubhangi Kulsange, Radhey Shyam Gupta, Rahul Thakur, Puneet Dewan, Catharina Boehme, Chinnambedu Nainarappan Paramsivan Background A critical challenge in providing TB care to People Living with HIV (PLHIV) is establishing an ...


Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization

06-Feb-2015 | Hideyuki Miyatake et al., PLoS ONE, 2015

by Hideyuki Miyatake, Akira Sanjoh, Satoru Unzai, Go Matsuda, Yuko Tatsumi, Yoichi Miyamoto, Naoshi Dohmae, Yoko Aida In this study, we determined the crystal structure of N-terminal importin-β-binding domain (IBB)-truncated human importin-α1 (ΔIBB-h-importin-α1) at 2.63 Å resolution. The ...


[Report] Origin of dramatic oxygen solute strengthening effect in titanium

06-Feb-2015 | Qian Yu; Liang Qi; Tomohito Tsuru; Rachel Traylor; David Rugg; J. W. Morris Jr.; Mark Asta; D. C. Chrzan; Andrew M. ..., Science , 2015

Structural alloys are often strengthened through the addition of solute atoms. However, given that solute atoms interact weakly with the elastic fields of screw dislocations, it has long been accepted that solution hardening is only marginally effective in materials with mobile screw ...


Probabilistic evaluation of integrating resource recovery into wastewater treatment to improve environmental sustainability [Sustainability Science]

03-Feb-2015 | Xu Wang; Perry L. McCarty; Junxin Liu; Nan-Qi Ren; Duu-Jong Lee; Han-Qing Yu; Yi Qian; Jiuhui Qu, Proceedings of the National Academy of Sciences current issue, 2015

Global expectations for wastewater service infrastructure have evolved over time, and the standard treatment methods used by wastewater treatment plants (WWTPs) are facing issues related to problem shifting due to the current emphasis on sustainability. A transition in WWTPs toward reuse of ...


Total Cellular Ca2+ Measurements in Yeast Using Flame Photometry

01-Feb-2015 | Tisi, R., Martegani, E., Brandao, R. L., CSH Protocols, 2015

A photoelectric flame photometer is a device used in inorganic chemical analysis for determining the concentrations of certain metals in solution. It does this by measuring the intensity of the light emitted by the metal when the solution is sprayed under controlled conditions into a nonluminous ...


Denaturation and Electrophoresis of RNA with Formaldehyde

01-Feb-2015 | Rio, D. C., CSH Protocols, 2015

Electrophoretic size fractionation can be used to denature and separate large mRNA molecules (0.5–10 kb) on formaldehyde-containing agarose gels. Formaldehyde contains a carbonyl group that reacts to form Schiff bases with the imino or amino groups of guanine, adenine, and cytosine. These ...


Characterization of Xanthophyll Pigments, Photosynthetic Performance, Photon Energy Dissipation, Reactive Oxygen Species Generation and Carbon Isotope Discrimination during Artemisinin-Induced Stress in Arabidopsis thaliana

30-Jan-2015 | M. Iftikhar Hussain et al., PLoS ONE, 2015

by M. Iftikhar Hussain, Manuel J. Reigosa Artemisinin, a potent antimalarial drug, is phytotoxic to many crops and weeds. The effects of artemisinin on stress markers, including fluorescence parameters, photosystem II photochemistry, photon energy dissipation, lipid peroxidation, reactive ...


[Report] High-efficiency solution-processed perovskite solar cells with millimeter-scale grains

30-Jan-2015 | Wanyi Nie; Hsinhan Tsai; Reza Asadpour; Jean-Christophe Blancon; Amanda J. Neukirch; Gautam Gupta; Jared J. Crochet; ..., Science , 2015

State-of-the-art photovoltaics use high-purity, large-area, wafer-scale single-crystalline semiconductors grown by sophisticated, high-temperature crystal growth processes. We demonstrate a solution-based hot-casting technique to grow continuous, pinhole-free thin films of organometallic ...


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