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Reply to Proenca et al.: Sown biodiverse pastures are not a universal solution to invasion risk [Biological Sciences]

07-Apr-2015 | Don A. Driscoll; Jane A. Catford; Jacob N. Barney; Philip E. Hulme; Inderjit; Tara G. Martin; Aníbal Pauchard; Petr ..., Proceedings of the National Academy of Sciences current issue, 2015

Proença et al. (1) highlight that sown biodiverse pastures (SBP) can provide local solutions that increase production while limiting the risk of new pasture taxa invading natural areas. We agree that in Portugal SBP is an innovative approach for reducing the weed risk. However, SBP does not offer ...


Diacerein Improves Left Ventricular Remodeling and Cardiac Function by Reducing the Inflammatory Response after Myocardial Infarction

27-Mar-2015 | Anali Galluce Torina et al., PLoS ONE, 2015

by Anali Galluce Torina, Karla Reichert, Fany Lima, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Helison Rafael Pereira do Carmo, Daniela Diógenes de Carvalho, Mário José Abdalla Saad, Andrei Carvalho Sposito, Orlando Petrucci Background The inflammatory response has ...


[Research Article] Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components

27-Mar-2015 | Thomas Gerling; Klaus F. Wagenbauer; Andrea M. Neuner; Hendrik Dietz, Science , 2015

We demonstrate that discrete three-dimensional (3D) DNA components can specifically self-assemble in solution on the basis of shape-complementarity and without base pairing. Using this principle, we produced homo- and heteromultimeric objects, including micrometer-scale one- and two-stranded ...


Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation [Biophysics and Computational Biology]

24-Mar-2015 | Jonggul Kim; Larry R. Masterson; Alessandro Cembran; Raffaello Verardi; Lei Shi; Jiali Gao; Susan S. Taylor; Gianlui ..., Proceedings of the National Academy of Sciences current issue, 2015

The dynamic interplay between kinases and substrates is crucial for the formation of catalytically committed complexes that enable phosphoryl transfer. However, a clear understanding on how substrates modulate kinase structural dynamics to control catalytic efficiency is still missing. Here, we ...


[Report] Multidimensional hierarchical self-assembly of amphiphilic cylindrical block comicelles

20-Mar-2015 | Huibin Qiu; Zachary M. Hudson; Mitchell A. Winnik; Ian Manners, Science , 2015

Self-assembly of molecular and block copolymer amphiphiles represents a well-established route to micelles with a wide variety of shapes and gel-like phases. We demonstrate an analogous process, but on a longer length scale, in which amphiphilic P-H-P and H-P-H cylindrical triblock comicelles ...


Energies, Vol. 8, Pages 2145-2164: Load Frequency Control in Isolated Micro-Grids with Electrical Vehicles Based on Multivariable Generalized Predictive Theory

18-Mar-2015 | Yang, Jun ; Zeng, Zhili ; Tang, Yufei ; Yan, Jun ; He, Haibo ; Wu, Yunliang, Energies, 2015

In power systems, although the inertia energy in power sources can partly cover power unbalances caused by load disturbance or renewable energy fluctuation, it is still hard to maintain the frequency deviation within acceptable ranges. However, with the vehicle-to-grid (V2G) technique, electric ...


Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution [Biochemistry]

17-Mar-2015 | Matthias Hillenbrand; Christian Schori; Jendrik Schöppe; Andreas Plückthun, Proceedings of the National Academy of Sciences current issue, 2015

Agonist binding to G-protein–coupled receptors (GPCRs) triggers signal transduction cascades involving heterotrimeric G proteins as key players. A major obstacle for drug design is the limited knowledge of conformational changes upon agonist binding, the details of interaction with the different ...


Nucleation of metastable aragonite CaCO3 in seawater [Applied Physical Sciences]

17-Mar-2015 | Wenhao Sun; Saivenkataraman Jayaraman; Wei Chen; Kristin A. Persson; Gerbrand Ceder, Proceedings of the National Academy of Sciences current issue, 2015

Predicting the conditions in which a compound adopts a metastable structure when it crystallizes out of solution is an unsolved and fundamental problem in materials synthesis, and one which, if understood and harnessed, could enable the rational design of synthesis pathways toward or away from ...


Spray-combustion synthesis: Efficient solution route to high-performance oxide transistors [Chemistry]

17-Mar-2015 | Xinge Yu; Jeremy Smith; Nanjia Zhou; Li Zeng; Peijun Guo; Yu Xia; Ana Alvarez; Stefano Aghion; Hui Lin; Junsheng Yu; ..., Proceedings of the National Academy of Sciences current issue, 2015

Metal-oxide (MO) semiconductors have emerged as enabling materials for next generation thin-film electronics owing to their high carrier mobilities, even in the amorphous state, large-area uniformity, low cost, and optical transparency, which are applicable to flat-panel displays, flexible ...


DNA Base Pair Resolution Measurements Using Resonance Energy Transfer Efficiency in Lanthanide Doped Nanoparticles

06-Mar-2015 | Aleksandra Delplanque et al., PLoS ONE, 2015

by Aleksandra Delplanque, Dominika Wawrzynczyk, Pawel Jaworski, Katarzyna Matczyszyn, Krzysztof Pawlik, Malcolm Buckle, Marcin Nyk, Claude Nogues, Marek Samoc Lanthanide-doped nanoparticles are of considerable interest for biodetection and bioimaging techniques thanks to their unique chemical ...


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