01-04-2013 | Ii-sei Watanabe; Fernando José Dias; João Paulo Mardegan Issa; Carlos Alexandre dos Santos Haemmerle; Diego Pulzatto ..., Journal of Electron Microscopy, 2013

The sensory nerve endings of the rat tongue, cheek and palate were studied using immunohistochemical staining and transmission electron microscopy analysis. The specimens were fixed in modified Karnovsky solution and embedded in Spurr resin. Substance P, calcitonin gene-related peptide ...

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01-03-2013 | Clare M. Mathes; Jillian R. Gregson; Alan C. Spector, Chemical Senses, 2013

Increased serotonergic activity has been shown to reduce motivation to ingest, which may involve, in part, gustatory processes. Here, we examined the effect of paroxetine, a selective serotonin reuptake inhibitor, on appetitive responding for a preferred and an avoided taste solution using a ...

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01-01-2013 | Kazumi Osada; Masaaki Hanawa; Kenji Tsunoda; Hiroshi Izumi, Chemical Senses, 2013

AbstractPrevious studies indicate that the most common result of mixing two odors is the decreased olfactory perception of one or both components in the mixture. An excellent example of this phenomenon is provided by the masking of an unpleasant odor by a pleasant odor. This study ...

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01-12-2012 | Shun Hirota; Mariko Ueda; Yugo Hayashi; Satoshi Nagao; Hironari Kamikubo; Mikio Kataoka, Journal of Biochemistry, 2012

We have previously shown that polymerization of cytochrome c (cyt c) occurs by successively domain swapping its C-terminal α-helix in the presence of ethanol. However, the factors that govern the conversion process of monomers to domain-swapped oligomers remain unknown. We found that ...

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01-11-2012 | Yi-Fen Kao; Yuan-Chao Lou; Yi-Hung Yeh; Chwan-Deng Hsiao; Chinpan Chen, Journal of Biochemistry, 2012

Chloroplasts protein precursors translated in the cytosol traverse the membranes to reach their intended destination with the help of translocon complexes called translocon at the outer envelope of chloroplasts and translocon at the inner envelope of chloroplasts (TIC), respectively. Two ...

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01-05-2012 | Lundström, Johan N.; Gordon, Amy R.; Wise, Paul; Frasnelli, Johannes, Chemical Senses, 2012

Taste, smell, and chemical irritation (so-called trigeminal sensation) combine in our daily experience to produce the supramodal sensation of flavor, are processed by partly overlapping neural mechanisms, and show functional interconnectivity in experiments. Given their collaboration in ...

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01-04-2012 | Tokuda, Naomi; Kawai, Katsuhisa; Lee, Young-Ho; Ikegami, Takahisa; Yamaguchi, Satoru; Yagisawa, Hitoshi; Fukui, Yasu ..., Journal of Biochemistry, 2012

Differences in the conformation of the pleckstrin homology (PH) domain of switch-associated protein-70 (SWAP-70) in solution and at the lipid bilayer membrane surface were examined using CD, fluorescence and NMR spectroscopy. Intracellular relocalization of SWAP-70 from the cytoplasm to the ...

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01-01-2012 | Burseg, Kerstin Martha Mensien; Ly Lieu, Hoang; Bult, Johannes Hendrikus Franciscus, Chemical Senses, 2012

Upon stimulation with continuously alternating (pulsatile) taste concentrations, humans report higher average taste intensities than for continuous stimulation with the same average tastant concentration. We investigated the effect of the magnitude of concentration changes (concentration ...

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01-12-2011 | Nakakoshi, Masamichi; Nishioka, Hideo; Katayama, Eisaku, Journal of Electron Microscopy, 2011

Aqueous uranyl acetate has been extensively used as a superb staining reagent for transmission electron microscopy of biological materials. However, recent regulation of nuclear fuel material severely restricts its use even for purely scientific purposes. Since uranyl salts are hazardous due ...

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01-12-2011 | Jung, Kwang Oh; Joo, Wonjong; Kim, Dong Hwan, Journal of Electron Microscopy, 2011

Noise is a primary issue in obtaining an image in a scanning microscope. This noise needs to be minimized in order to have a clear image of the sample in case of a nanosize level measurement. In this work, we propose a method to improve the image quality by applying dither signal injection ...

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