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178 Newest Publications about the topic solution

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Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution [Biochemistry]

17-Mar-2015 | Matthias Hillenbrand; Christian Schori; Jendrik Schöppe; Andreas Plückthun, Proceedings of the National Academy of Sciences current issue, 2015

Agonist binding to G-protein–coupled receptors (GPCRs) triggers signal transduction cascades involving heterotrimeric G proteins as key players. A major obstacle for drug design is the limited knowledge of conformational changes upon agonist binding, the details of interaction with the different ...

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Probabilistic evaluation of integrating resource recovery into wastewater treatment to improve environmental sustainability [Sustainability Science]

03-Feb-2015 | Xu Wang; Perry L. McCarty; Junxin Liu; Nan-Qi Ren; Duu-Jong Lee; Han-Qing Yu; Yi Qian; Jiuhui Qu, Proceedings of the National Academy of Sciences current issue, 2015

Global expectations for wastewater service infrastructure have evolved over time, and the standard treatment methods used by wastewater treatment plants (WWTPs) are facing issues related to problem shifting due to the current emphasis on sustainability. A transition in WWTPs toward reuse of ...

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Molecular-dynamics simulations of urea nucleation from aqueous solution [Chemistry]

06-Jan-2015 | Matteo Salvalaglio; Claudio Perego; Federico Giberti; Marco Mazzotti; Michele Parrinello, Proceedings of the National Academy of Sciences current issue, 2015

Despite its ubiquitous character and relevance in many branches of science and engineering, nucleation from solution remains elusive. In this framework, molecular simulations represent a powerful tool to provide insight into nucleation at the molecular scale. In this work, we combine theory and ...

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Flagellated bacterial motility in polymer solutions [Physics]

16-Dec-2014 | Vincent A. Martinez; Jana Schwarz-Linek; Mathias Reufer; Laurence G. Wilson; Alexander N. Morozov; Wilson C. K. Poon, Proceedings of the National Academy of Sciences current issue, 2014

It is widely believed that the swimming speed, v, of many flagellated bacteria is a nonmonotonic function of the concentration, c, of high-molecular-weight linear polymers in aqueous solution, showing peaked v(c) curves. Pores in the polymer solution were suggested as the explanation. Quantifying ...

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Observation of ice-like water layers at an aqueous protein surface [Biophysics and Computational Biology]

16-Dec-2014 | Konrad Meister; Simona Strazdaite; Arthur L. DeVries; Stephan Lotze; Luuk L. C. Olijve; Ilja K. Voets; Huib J. Bakker, Proceedings of the National Academy of Sciences current issue, 2014

We study the properties of water at the surface of an antifreeze protein with femtosecond surface sum frequency generation spectroscopy. We find clear evidence for the presence of ice-like water layers at the ice-binding site of the protein in aqueous solution at temperatures above the freezing ...

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Microtubule nucleation remote from centrosomes may explain how asters span large cells [Applied Physical Sciences]

16-Dec-2014 | Keisuke Ishihara; Phuong A. Nguyen; Aaron C. Groen; Christine M. Field; Timothy J. Mitchison, Proceedings of the National Academy of Sciences current issue, 2014

A major challenge in cell biology is to understand how nanometer-sized molecules can organize micrometer-sized cells in space and time. One solution in many animal cells is a radial array of microtubules called an aster, which is nucleated by a central organizing center and spans the entire ...

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In This Issue [This Week in PNAS]

09-Dec-2014 | Proceedings of the National Academy of Sciences current issue, 2014

Chemical gardens in quasi-2D Chemical gardens in confined geometry. When clumps of some solid metal salts are dropped into an anionic solution such as water glass, the salts tend to precipitate into a dazzling array of crystals with tendrils and offshoots that resemble a lush garden. Chemical ...

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Multiple patterns of polymer gels in microspheres due to the interplay among phase separation, wetting, and gelation [Applied Physical Sciences]

11-Nov-2014 | Miho Yanagisawa; Shinpei Nigorikawa; Takahiro Sakaue; Kei Fujiwara; Masayuki Tokita, Proceedings of the National Academy of Sciences current issue, 2014

We report the spontaneous patterning of polymer microgels by confining a polymer blend within microspheres. A poly(ethylene glycol) (PEG) and gelatin solution was confined inside water-in-oil (W/O) microdroplets coated with a layer of zwitterionic lipids: dioleoylphosphatidylethanolamine (PE) and ...

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Migrant solution to the anammox mystery [Earth, Atmospheric, and Planetary Sciences]

04-Nov-2014 | Cecelia C. S. Hannides, Proceedings of the National Academy of Sciences current issue, 2014

Every night a massive migration takes place in ocean waters. Zooplankton and micronekton, a diverse group of organisms <1 mm to 10 cm in size, swim up from midwater depths (200–700 m) to the surface ocean to feed and return down to resting depths before daybreak. The importance of this...

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Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase [Microbiology]

04-Nov-2014 | Valjean R. Bacot-Davis; Jessica J. Ciomperlik; Holly A. Basta; Claudia C. Cornilescu; Ann C. Palmenberg, Proceedings of the National Academy of Sciences current issue, 2014

Cardiovirus Leader (L) proteins induce potent antihost inhibition of active cellular nucleocytoplasmic trafficking by triggering aberrant hyperphosphorylation of nuclear pore proteins (Nup). To achieve this, L binds protein RanGTPase (Ran), a key trafficking regulator, and diverts it into ...

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