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Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles

31-Jul-2015 | Hyo-Jick Choi et al., PLoS ONE, 2015

by Hyo-Jick Choi, Jae-Min Song, Brian J. Bondy, Richard W. Compans, Sang-Moo Kang, Mark R. Prausnitz Enveloped virus vaccines can be damaged by high osmotic strength solutions, such as those used to protect the vaccine antigen during drying, which contain high concentrations of sugars. We ...

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Monitoring of Water Spectral Pattern Reveals Differences in Probiotics Growth When Used for Rapid Bacteria Selection

02-Jul-2015 | Aleksandar Slavchev et al., PLoS ONE, 2015

by Aleksandar Slavchev, Zoltan Kovacs, Haruki Koshiba, Airi Nagai, György Bázár, Albert Krastanov, Yousuke Kubota, Roumiana Tsenkova Development of efficient screening method coupled with cell functionality evaluation is highly needed in contemporary microbiology. The presented novel concept ...

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"Just Another Tool for Online Studies” (JATOS): An Easy Solution for Setup and Management of Web Servers Supporting Online Studies

26-Jun-2015 | Kristian Lange et al., PLoS ONE, 2015

by Kristian Lange, Simone Kühn, Elisa Filevich We present here “Just Another Tool for Online Studies” (JATOS): an open source, cross-platform web application with a graphical user interface (GUI) that greatly simplifies setting up and communicating with a web server to host online studies that ...

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Trends in Longevity in the Americas: Disparities in Life Expectancy in Women and Men, 1965-2010

19-Jun-2015 | Ian R. Hambleton et al., PLoS ONE, 2015

by Ian R. Hambleton, Christina Howitt, Selvi Jeyaseelan, Madhuvanti M. Murphy, Anselm J Hennis, Rainford Wilks, E. Nigel Harris, Marlene MacLeish, Louis Sullivan, U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR) Objective We describe trends in life expectancy at birth ...

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Impact of the Quality of Bowel Cleansing on the Efficacy of Colonic Cancer Screening: A Prospective, Randomized, Blinded Study

07-May-2015 | Jürgen Pohl et al., PLoS ONE, 2015

by Jürgen Pohl, Marc Halphen, Hans Rudolf Kloess, Wolfgang Fischbach Objectives Efficacy of two low volume bowel cleansing preparations, polyethylene glycol plus ascorbate (PEG+Asc) and sodium picosulfate/magnesium citrate (NaPic/MgCit), were compared for polyp and adenoma detection rate (PDR ...

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Spectral Properties of Single Gold Nanoparticles in Close Proximity to Biological Fluorophores Excited by 2-Photon Excitation

24-Apr-2015 | Andrea Anzalone et al., PLoS ONE, 2015

by Andrea Anzalone, Manuela Gabriel, Laura C. Estrada, Enrico Gratton Metallic nanoparticles (NPs) are able to modify the excitation and emission rates (plasmonic enhancement) of fluorescent molecules in their close proximity. In this work, we measured the emission spectra of 20 nm Gold ...

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Diacerein Improves Left Ventricular Remodeling and Cardiac Function by Reducing the Inflammatory Response after Myocardial Infarction

27-Mar-2015 | Anali Galluce Torina et al., PLoS ONE, 2015

by Anali Galluce Torina, Karla Reichert, Fany Lima, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Helison Rafael Pereira do Carmo, Daniela Diógenes de Carvalho, Mário José Abdalla Saad, Andrei Carvalho Sposito, Orlando Petrucci Background The inflammatory response has ...

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DNA Base Pair Resolution Measurements Using Resonance Energy Transfer Efficiency in Lanthanide Doped Nanoparticles

06-Mar-2015 | Aleksandra Delplanque et al., PLoS ONE, 2015

by Aleksandra Delplanque, Dominika Wawrzynczyk, Pawel Jaworski, Katarzyna Matczyszyn, Krzysztof Pawlik, Malcolm Buckle, Marcin Nyk, Claude Nogues, Marek Samoc Lanthanide-doped nanoparticles are of considerable interest for biodetection and bioimaging techniques thanks to their unique chemical ...

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Conformational Changes in a Hyperthermostable Glycoside Hydrolase: Enzymatic Activity Is a Consequence of the Loop Dynamics and Protonation Balance

27-Feb-2015 | Leandro C. de Oliveira et al., PLoS ONE, 2015

by Leandro C. de Oliveira, Viviam M. da Silva, Francieli Colussi, Aline D. Cabral, Mario de Oliveira Neto, Fabio M. Squina, Wanius Garcia Endo-β-1, 4-mannanase from Thermotoga petrophila (TpMan) is a modular hyperthermostable enzyme involved in the degradation of mannan-containing ...

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Catching the Missing Million: Experiences in Enhancing TB & DR-TB Detection by Providing Upfront Xpert MTB/RIF Testing for People Living with HIV in India

06-Feb-2015 | Neeraj Raizada et al., PLoS ONE, 2015

by Neeraj Raizada, Kuldeep Singh Sachdeva, Achuthan Sreenivas, Shubhangi Kulsange, Radhey Shyam Gupta, Rahul Thakur, Puneet Dewan, Catharina Boehme, Chinnambedu Nainarappan Paramsivan Background A critical challenge in providing TB care to People Living with HIV (PLHIV) is establishing an ...

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