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Impact of the Quality of Bowel Cleansing on the Efficacy of Colonic Cancer Screening: A Prospective, Randomized, Blinded Study

07-May-2015 | Jürgen Pohl et al., PLoS ONE, 2015

by Jürgen Pohl, Marc Halphen, Hans Rudolf Kloess, Wolfgang Fischbach Objectives Efficacy of two low volume bowel cleansing preparations, polyethylene glycol plus ascorbate (PEG+Asc) and sodium picosulfate/magnesium citrate (NaPic/MgCit), were compared for polyp and adenoma detection rate (PDR ...


Spectral Properties of Single Gold Nanoparticles in Close Proximity to Biological Fluorophores Excited by 2-Photon Excitation

24-Apr-2015 | Andrea Anzalone et al., PLoS ONE, 2015

by Andrea Anzalone, Manuela Gabriel, Laura C. Estrada, Enrico Gratton Metallic nanoparticles (NPs) are able to modify the excitation and emission rates (plasmonic enhancement) of fluorescent molecules in their close proximity. In this work, we measured the emission spectra of 20 nm Gold ...


Diacerein Improves Left Ventricular Remodeling and Cardiac Function by Reducing the Inflammatory Response after Myocardial Infarction

27-Mar-2015 | Anali Galluce Torina et al., PLoS ONE, 2015

by Anali Galluce Torina, Karla Reichert, Fany Lima, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Helison Rafael Pereira do Carmo, Daniela Diógenes de Carvalho, Mário José Abdalla Saad, Andrei Carvalho Sposito, Orlando Petrucci Background The inflammatory response has ...


DNA Base Pair Resolution Measurements Using Resonance Energy Transfer Efficiency in Lanthanide Doped Nanoparticles

06-Mar-2015 | Aleksandra Delplanque et al., PLoS ONE, 2015

by Aleksandra Delplanque, Dominika Wawrzynczyk, Pawel Jaworski, Katarzyna Matczyszyn, Krzysztof Pawlik, Malcolm Buckle, Marcin Nyk, Claude Nogues, Marek Samoc Lanthanide-doped nanoparticles are of considerable interest for biodetection and bioimaging techniques thanks to their unique chemical ...


Conformational Changes in a Hyperthermostable Glycoside Hydrolase: Enzymatic Activity Is a Consequence of the Loop Dynamics and Protonation Balance

27-Feb-2015 | Leandro C. de Oliveira et al., PLoS ONE, 2015

by Leandro C. de Oliveira, Viviam M. da Silva, Francieli Colussi, Aline D. Cabral, Mario de Oliveira Neto, Fabio M. Squina, Wanius Garcia Endo-β-1, 4-mannanase from Thermotoga petrophila (TpMan) is a modular hyperthermostable enzyme involved in the degradation of mannan-containing ...


Catching the Missing Million: Experiences in Enhancing TB & DR-TB Detection by Providing Upfront Xpert MTB/RIF Testing for People Living with HIV in India

06-Feb-2015 | Neeraj Raizada et al., PLoS ONE, 2015

by Neeraj Raizada, Kuldeep Singh Sachdeva, Achuthan Sreenivas, Shubhangi Kulsange, Radhey Shyam Gupta, Rahul Thakur, Puneet Dewan, Catharina Boehme, Chinnambedu Nainarappan Paramsivan Background A critical challenge in providing TB care to People Living with HIV (PLHIV) is establishing an ...


Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization

06-Feb-2015 | Hideyuki Miyatake et al., PLoS ONE, 2015

by Hideyuki Miyatake, Akira Sanjoh, Satoru Unzai, Go Matsuda, Yuko Tatsumi, Yoichi Miyamoto, Naoshi Dohmae, Yoko Aida In this study, we determined the crystal structure of N-terminal importin-β-binding domain (IBB)-truncated human importin-α1 (ΔIBB-h-importin-α1) at 2.63 Å resolution. The ...


Characterization of Xanthophyll Pigments, Photosynthetic Performance, Photon Energy Dissipation, Reactive Oxygen Species Generation and Carbon Isotope Discrimination during Artemisinin-Induced Stress in Arabidopsis thaliana

30-Jan-2015 | M. Iftikhar Hussain et al., PLoS ONE, 2015

by M. Iftikhar Hussain, Manuel J. Reigosa Artemisinin, a potent antimalarial drug, is phytotoxic to many crops and weeds. The effects of artemisinin on stress markers, including fluorescence parameters, photosystem II photochemistry, photon energy dissipation, lipid peroxidation, reactive ...


Solution Structure of the SGTA Dimerisation Domain and Investigation of Its Interactions with the Ubiquitin-Like Domains of BAG6 and UBL4A

21-Nov-2014 | John F. Darby et al., PLoS ONE, 2014

by John F. Darby, Ewelina M. Krysztofinska, Peter J. Simpson, Aline C. Simon, Pawel Leznicki, Newran Sriskandarajah, David S. Bishop, Lisa R. Hale, Caterina Alfano, Maria R. Conte, Santiago Martínez-Lumbreras, Arjun Thapaliya, Stephen High, Rivka L. Isaacson Background The BAG6 complex resides ...


Real-Time UV-Visible Spectroscopy Analysis of Purple Membrane-Polyacrylamide Film Formation Taking into Account Fano Line Shapes and Scattering

17-Oct-2014 | María Gomariz et al., PLoS ONE, 2014

by María Gomariz, Salvador Blaya, Pablo Acebal, Luis Carretero We theoretically and experimentally analyze the formation of thick Purple Membrane (PM) polyacrylamide (PA) films by means of optical spectroscopy by considering the absorption of bacteriorhodopsin and scattering. We have applied ...


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