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3,030 Newest Publications about the topic viruses

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Rethinking the capsid proteins of enveloped viruses: multifunctionality from genome packaging to genome transfection

21-Mar-2015 | João Freire, Nuno C. Santos, Ana Salomé Veiga, Andr ea T. Da Poian, Miguel A. R. B. Castanho, FEBS Journal, 2015

Abstract Regardless of the debate on if there is a place for viruses in the tree of life, it is consensual that they co‐evolve with their hosts under the pressure of genome minimization. The abundance of multifunctional viral structural proteins is a consequence of this pressure. The molecular ...

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Structure Determination of Feline Calicivirus Virus-Like Particles in the Context of a Pseudo-Octahedral Arrangement

20-Mar-2015 | Wim P. Burmeister et al., PLoS ONE, 2015

by Wim P. Burmeister, Marlyse Buisson, Leandro F. Estrozi, Guy Schoehn, Olivier Billet, Zahia Hannas, Cécile Sigoillot, Hervé Poulet The vesivirus feline calicivirus (FCV) is a positive strand RNA virus encapsidated by an icosahedral T=3 shell formed by the viral VP1 protein. Upon its ...

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Association between Free Testosterone Levels and Anal Human Papillomavirus Types 16/18 Infections in a Cohort of Men Who Have Sex with Men

20-Mar-2015 | Hilary K. Hsu et al., PLoS ONE, 2015

by Hilary K. Hsu, Todd T. Brown, Xiuhong Li, Stephen Young, Ross D. Cranston, Gypsyamber D’Souza, Lisa P. Jacobson, Otoniel Martínez-Maza, Eric C. Seaberg, Joseph B. Margolick, Frank J. Jenkins, Matthew G. Moran, Kristofer Chua, Robert K. Bolan, Roger Detels, Dorothy J. Wiley Background Human ...

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The Cost-Effectiveness of Monitoring Strategies for Antiretroviral Therapy of HIV Infected Patients in Resource-Limited Settings: Software Tool

20-Mar-2015 | Janne Estill et al., PLoS ONE, 2015

by Janne Estill, Luisa Salazar-Vizcaya, Nello Blaser, Matthias Egger, Olivia Keiser Background The cost-effectiveness of routine viral load (VL) monitoring of HIV-infected patients on antiretroviral therapy (ART) depends on various factors that differ between settings and across time. Low-cost ...

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Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1

20-Mar-2015 | Li J; Xu F; Hu S; Zhou J; Mei S; Zhao X; Cen S; Jin Q; Liang C; Guo F, Biochemical Journal, 2015

The SAM domain and HD domain containing protein 1 (SAMHD1) inhibits HIV-1 infection of myeloid cells and resting CD4+ T cells. Two lineages of primate lentiviruses, the sooty mangabey SIV (SIVsm)/macaque SIV (SIVmac)/HIV-2 lineage and the red-capped mangabey SIV (SIVrcm) lineage, carry a SAMHD1 ...

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A continuous peptide epitope reacting with pandemic influenza AH1N1 predicted by bioinformatic approaches

18-Mar-2015 | Jonathan P. Carrillo‐Vazquez, José Correa‐Basurto, Jazmin García‐Machorro, Rafael Campos‐Rodríguez, Violaine Moreau, ..., Journal of Molecular Recognition, 2015

Computational identification of potential epitopes with an immunogenic capacity challenges immunological research. Several methods show considerable success, and together with experimental studies, the efficiency of the algorithms to identify potential peptides with biological activity has ...

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IJERPH, Vol. 12, Pages 3264-3292: On the Road to HIV/AIDS Competence in the Household: Building a Health-Enabling Environment for People Living with HIV/AIDS

18-Mar-2015 | Masquillier, Caroline ; Wouters, Edwin ; Mortelmans, Dimitri ; van Wyk, Brian, International Journal of Environmental Research and Public Health, 2015

When aiming to provide chronic disease care within the context of human resource shortages, we should not only consider the responsibility of the individual person living with HIV/AIDS (PLWHA) but also the capacity of the social environment to actively encourage a lifestyle that fosters health. ...

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Branched dimerization of Tat peptide improves permeability to HeLa and hippocampal neuronal cells

18-Mar-2015 | I. Abrrey Monreal; Qian Liu; Katherine Tyson; Tyler Bland; Doralyn S. Dalisay; Erin V. Adams; Gary A. Wayman; Hector ..., Chemical Communication, 2015

A dimeric branched peptide TATp-D designed as an analogue of the HIV-Tat protein transduction domain (TATp), a prototypical cell penetrating peptide (CPP), demonstrates significantly enhanced cell uptake at 0.25 to 2.5 μM. Live cell confocal laser scanning microscopy revealed that multivalency ...

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Development of the resolution theory for gradient insulator‐based Dielectrophoresis

17-Mar-2015 | Paul V. Jones, Mark A. Hayes, ELECTROPHORESIS, 2015

New and important separations capabilities are being enabled by utilizing other electric field‐induced forces besides electrophoresis, among these is dielectrophoresis. Recent works have used experimentally simple insulator‐based systems that induce field gradients creating dielectrophoretic ...

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Origin of the HIV-1 group O epidemic in western lowland gorillas [Microbiology]

17-Mar-2015 | Mirela D’arc; Ahidjo Ayouba; Amandine Esteban; Gerald H. Learn; Vanina Boué; Florian Liegeois; Lucie Etienne; Nikki ..., Proceedings of the National Academy of Sciences current issue, 2015

HIV-1, the cause of AIDS, is composed of four phylogenetic lineages, groups M, N, O, and P, each of which resulted from an independent cross-species transmission event of simian immunodeficiency viruses (SIVs) infecting African apes. Although groups M and N have been traced to geographically ...

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