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4,144 Newest Publications about the topic viruses


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Photopicking: In Situ Approach for Site‐Specific Attachment of Single Multiprotein Nanoparticles to Atomic Force Microscopy Tips

13-Jan-2017 | Ivan Liashkovich, Gonzalo Rosso, Martina Rangl, Andreas Ebner, Wali Hafezi, Joachim Kühn, Peter Schön, Peter Hinterd ..., Advanced Functional Materials, 2017

Ligand–receptor interactions are fundamental in life sciences and include hormone–receptor, protein–protein, pathogen–host, and cell–cell interactions, among others. Atomic force microscopy (AFM) proved to be invaluable for scrutinizing ligand–receptor interactions at the single molecular level. ...


Molecules, Vol. 22, Pages 130: Synthesis, Structure and Antimicrobial Properties of Novel Benzalkonium Chloride Analogues with Pyridine Rings

13-Jan-2017 | Brycki, Bogumił ; Małecka, Izabela ; Koziróg, Anna ; Otlewska, Anna, Molecules, 2017

Quaternary ammonium compounds (QACs) are a group of compounds of great economic significance. They are widely used as emulsifiers, detergents, solubilizers and corrosion inhibitors in household and industrial products. Due to their excellent antimicrobial activity QACs have also gained a special ...


[In Brief] News at a glance

13-Jan-2017 | American Association for the Advancement of Science, Science , 2017

SCI COMMUNIn science news around the world, U.S. officials release a plan to help agencies decide whether to fund controversial studies that make viruses more dangerous, a new survey of U.K. academics finds that 90% still think universities will be harmed by the country's departure from the ...


IJERPH, Vol. 14, Pages 69: Knowledge and Attitudes of Dentists with Respect to the Risks of Blood-Borne Pathogens—A Cross-Sectional Study in Poland

12-Jan-2017 | Garus-Pakowska, Anna ; Górajski, Mariusz ; Szatko, Franciszek, International Journal of Environmental Research and Public Health, 2017

Background: To analyze dentists’ knowledge of blood-borne infections, their attitudes towards infected patients, and to determine the frequency of the contact with infectious material; Methods: We surveyed 192 dentists using an anonymous questionnaire. Results: Only a quarter of dentists ...


M1 aminopeptidases as drug targets: broad applications or therapeutic niche?

11-Jan-2017 | Nyssa Drinkwater, Jisook Lee, Wei Yang, Tess R. Malcolm, Sheena McGowan, FEBS Journal, 2017

Abstract M1 aminopeptidase enzymes are a diverse family of metalloenzymes characterized by conserved structure and reaction specificity. Excluding viruses, M1 aminopeptidases are distributed throughout all phyla, and have been implicated in a wide range of functions including cell maintenance, ...


Immunological Principles Guiding the Rational Design of Particles for Vaccine Delivery

11-Jan-2017 | Katelyn T. Gause; Adam K. Wheatley; Jiwei Cui; Yan Yan; Stephen J. Kent; Frank Caruso, ACS Nano, 2017

Despite the immense public health successes of immunization over the past century, effective vaccines are still lacking for globally important pathogens such as human immunodeficiency virus, malaria, and tuberculosis. Exciting recent advances in immunology and biotechnology over the past few ...


Molecules, Vol. 22, Pages 116: Radix isatidis Polysaccharides Inhibit Influenza a Virus and Influenza A Virus-Induced Inflammation via Suppression of Host TLR3 Signaling In Vitro

11-Jan-2017 | Li, Zhengtu ; Li, Li ; Zhou, Hongxia ; Zeng, Lijuan ; Chen, Tingting ; Chen, Qiaolian ; Zhou, Beixian ; Wang, Yutao ..., Molecules, 2017

Influenza remains one of the major epidemic diseases worldwide, and rapid virus replication and collateral lung tissue damage caused by excessive pro-inflammatory host immune cell responses lead to high mortality rates. Thus, novel therapeutic agents that control influenza A virus (IAV) ...


Highly Uniform Gold Nanobipyramids for Ultrasensitive Colorimetric Detection of Influenza Virus

10-Jan-2017 | Shaohua Xu; Wenjun Ouyang; Peisi Xie; Yi Lin; Bin Qiu; Zhenyu Lin; Guonan Chen; Longhua Guo, Analytical Chemistry, 2017

Gold nanoparticles (AuNPs) have been frequently utilized for the construction of diverse colorimetric biosensors. Normally, AuNPs with sharp edges could have better sensitivity. However, the poor monodipersity of AuNPs with sharp edges seriously confines their utility for colorimetric biosensing. ...


IJMS, Vol. 18, Pages 126: The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention

10-Jan-2017 | González, María Eugenia, International Journal of Molecular Sciences, 2017

The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for antiretroviral drug development. The conservation both of the structure along virus evolution and the amino acid sequence in viral isolates from patients underlines the importance of Vpr for the establishment ...


Molecularly imprinted polymer-based core-shells (solid vs hollow) @ pencil graphite electrode for electrochemical sensing of certain anti-HIV drugs

07-Jan-2017 | Author(s): Bhim Bali Prasad, Kislay Singh, Sensors and Actuators B: Chemical, 2017

Publication date: June 2017 Source:Sensors and Actuators B: Chemical, Volume 244 Author(s): Bhim Bali Prasad, Kislay Singh The present work describes a new, simple, and easy method for the fabrication of molecularly imprinted polymer-based core-shells (solid and hollow) @ pencil ...


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