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4,632 Newest Publications about the topic viruses

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IJMS, Vol. 19, Pages 239: Implication of Soluble Forms of Cell Adhesion Molecules in Infectious Disease and Tumor: Insights from Transgenic Animal Models

13-Jan-2018 | Ono, Etsuro ; Uede, Toshimitsu, International Journal of Molecular Sciences, 2018

IJMS, Vol. 19, Pages 239: Implication of Soluble Forms of Cell Adhesion Molecules in Infectious Disease and Tumor: Insights from Transgenic Animal Models International Journal of Molecular Sciences doi: 10.3390/ijms19010239 Authors: Etsuro Ono Toshimitsu Uede Cell adhesion ...

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Syntheses of (−)-Tripterifordin and (−)-Neotripterifordin from Stevioside

12-Jan-2018 | Shoji Kobayashi; Keisuke Shibukawa; Yoshiki Hamada; Takuma Kuruma; Asako Kawabata; Araki Masuyama, The Journal of Organic Chemistry, 2018

We report short syntheses of (−)-tripterifordin and (−)-neotripterifordin, potent inhibitors of HIV replication, from stevioside, a natural sweetener used worldwide. The key transformations are reduction at C13 through the formation of a tertiary chloride and subsequent three-step lactonization ...

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Syntheses of (−)-Tripterifordin and (−)-Neotripterifordin from Stevioside

12-Jan-2018 | Shoji Kobayashi; Keisuke Shibukawa; Yoshiki Hamada; Takuma Kuruma; Asako Kawabata; Araki Masuyama, The Journal of Organic Chemistry, 2018

We report short syntheses of (−)-tripterifordin and (−)-neotripterifordin, potent inhibitors of HIV replication, from stevioside, a natural sweetener used worldwide. The key transformations are reduction at C13 through the formation of a tertiary chloride and subsequent three-step lactonization ...

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SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis

12-Jan-2018 | Xiangming Ding; Dongxiao Li; Mengke Li; Han Wang; Qin He; Yunwu Wang; Hongbing Yu; Dean Tian; Qin Yu, Laboratory Investigation, 2018

SLC26A3 encodes a Cl−/HCO3− ion transporter that is also known as downregulated in adenoma (DRA) and is involved in HCO3−/mucus formation. The role of DRA in the epithelial barrier has not been previously established. In this study, we investigated the in vivo and in vitro mechanisms of DRA in ...

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SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis

12-Jan-2018 | Xiangming Ding; Dongxiao Li; Mengke Li; Han Wang; Qin He; Yunwu Wang; Hongbing Yu; Dean Tian; Qin Yu, Laboratory Investigation, 2018

SLC26A3 encodes a Cl−/HCO3− ion transporter that is also known as downregulated in adenoma (DRA) and is involved in HCO3−/mucus formation. The role of DRA in the epithelial barrier has not been previously established. In this study, we investigated the in vivo and in vitro mechanisms of DRA in ...

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Molecular characterization and gene silencing of Laccase 1 in the grain aphid, Sitobion avenae

11-Jan-2018 | Yong Zhang, Jia Fan, Frédéric Francis, Julian Chen, Archives of Insect Biochemistry and Physiology, 2018

Abstract Laccase 1 (Lac1), a polyphenol oxidase, has been proposed to be involved in insect iron metabolism and immunity responses. However, little information is available on the roles of Lac 1 in insect–plant interactions. The grain aphid Sitobion avenae is one of the most destructive pests ...

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Detection of foodborne viruses in ready‐to‐eat meat products and meat processing plants

09-Jan-2018 | Nikolas Markantonis, Petra Vasickova, Monika Kubankova, Pavel Mikel, George Botsaris, Journal of Food Safety, 2018

Abstract Several studies have confirmed the presence of foodborne viruses in different food products throughout the world. There is accumulating data suggesting that the economic burden of foodborne viral infections is rising, making the understanding and monitoring of their prevalence a ...

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Development and Validation of an Assay to Analyze Atazanavir in Human Hair Via Liquid Chromatography‐Tandem Mass Spectrometry (LC‐MS/MS)

09-Jan-2018 | Nhi Phung, Karen Kuncze, Hideaki Okochi, Alexander Louie, Leslie Z. Benet, Igho Ofokotun, David W. Haas, Judith S. C ..., Rapid Communications in Mass Spectrometry, 2018

Abstract Assays to quantify antiretrovirals in hair samples are increasingly used to monitor adherence and exposure in both HIV prevention and treatment studies. Atazanavir (ATV) is a protease inhibitor used in combination antiretroviral therapy (ART). We developed and validated a liquid ...

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Programmable Nucleic Acid Nanoswitches for the Rapid, Single-Step Detection of Antibodies in Bodily Fluids

09-Jan-2018 | Alessandro Porchetta; Rudy Ippodrino; Bruna Marini; Arnaldo Caruso; Francesca Caccuri; Francesco Ricci, Journal of the American Chemical Society, 2018

Antibody detection plays a pivotal role in the diagnosis of pathogens and monitoring the success of vaccine immunization. However, current serology techniques require multiple, time-consuming washing and incubation steps, which limit their applicability in point-of-care (POC) diagnostics and ...

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Colorimetric molecular diagnosis of HIV gag gene using DNAzyme and a complementary DNA-extended primer

30-Dec-2017 | Seong U Kim; Bhagwan Sahebrao Batule; Hyoyoung Mun; Ju-Young Byun; Won-Bo Shim; Min-Gon Kim, Analyst, 2017

We have developed a novel strategy for the colorimetric detection of PCR products by utilizing target-specific primer modified at the 5’-end with an anti-DNAzyme sequence. Single-stranded DNAzyme sequence folds into a G-quadruplex structure with hemin and shows strong peroxidase activity. When ...

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