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2,698 Newest Publications about the topic viruses


[Technical Comment] Comment on “Influence of HLA-C Expression Level on HIV Control”

13-09-2013 | Elisa Lo Monaco; Elisa Tremante; Priscilla Biswas; Martin P. Cranage; Donato Zipeto; Alberto Beretta; Patrizio Giacomini, Science , 2013

Apps et al. (Reports, 5 April 2013, p. 87) found that high human leukocyte antigen C (HLA-C) expression favors HIV-1 control. However, as noted here, HLA-C was assessed with a monoclonal antibody (DT9) that cross-reacts with HLA-E. In the context of the available evidence, this is consistent with ...


[Special Issue Review] Antibodies in HIV-1 Vaccine Development and Therapy

13-09-2013 | Florian Klein; Hugo Mouquet; Pia Dosenovic; Johannes F. Scheid; Louise Scharf; Michel C. Nussenzweig, Science , 2013

Despite 30 years of study, there is no HIV-1 vaccine and, until recently, there was little hope for a protective immunization. Renewed optimism in this area of research comes in part from the results of a recent vaccine trial and the use of single-cell antibody-cloning techniques that uncovered ...


[News Focus] Bound for Glory

13-09-2013 | Jon Cohen, Science , 2013

The discovery of antibodies that foil almost every HIV variant has transformed the AIDS vaccine search. Author: Jon Cohen


[News of the Week] Around the World

13-09-2013 | Science , 2013

In science news around the world, the G20 group of industrialized nations has agreed to limit emissions of harmful refrigerants, an Indian parliamentary panel blasts a U.S. nonprofit for alleged ethical lapses in a trial of an HPV vaccine in the country, plans for a Spanish particle accelerator ...


[Technical Response] Response to Comment on “Influence of HLA-C Expression Level on HIV Control”

13-09-2013 | Richard Apps; Mary Carrington, Science , 2013

Lo Monaco et al. propose that human leukocyte antigen E (HLA-E) and HLA-C expression levels both contribute to HIV control. The minimal, flat level of cell surface HLA-E detectable by staining with available HLA-E–specific antibodies questions a role for differential HLA-E expression in ...


[Podcast] Science Podcast: 13 September Show

13-09-2013 | Science , 2013

Listen to stories on DNA and disasters, new immunological weapons against HIV, Voyager's latest exit, and more,


Fluorescent Imaging of Single Nanoparticles and Viruses on a Smart Phone

12-09-2013 | Qingshan Wei; Hangfei Qi; Wei Luo; Derek Tseng; So Jung Ki; Zhe Wan; Zoltán Göröcs; Laurent A. Bentolila; Ting-Ting ..., ACS Nano, 2013

Optical imaging of nanoscale objects, whether it is based on scattering or fluorescence, is a challenging task due to reduced detection signal-to-noise ratio and contrast at subwavelength dimensions. Here, we report a field-portable fluorescence microscopy platform installed on a smart phone for ...


Crystallization, structural diversity and anisotropy effects in 2D arrays of icosahedral viruses

11-09-2013 | Masafumi Fukuto; Quyen L. Nguyen; Oleg Vasilyev; Nick Mank; Clorissa L. Washington-Hughes; Ivan Kuzmenko; Antonio Ch ..., Soft Matter, 2013

We investigate two-dimensional (2D) assembly of the icosahedral turnip yellow mosaic virus (TYMV) under cationic lipid monolayers at the aqueous solution–vapor interface. The 2D crystallization of TYMV has been achieved by enhancing electrostatically induced interfacial adsorption, an approach ...


IJERPH, Vol. 10, Pages 4200-4223: A Review of Vaccine Approaches for West Nile Virus

10-09-2013 | Iyer, Arun V.; Kousoulas, Konstantin G., International Journal of Environmental Research and Public Health, 2013

The West Nile virus (WNC) first appeared in North America in 1999. The North American lineages of WNV were characterized by the presence of neuroinvasive and neurovirulent strains causing disease and death in humans, birds and horses. The 2012 WNV season in the United States saw a massive spike ...


Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor

09-09-2013 | Author(s): Shadia A. Galal , Ahmed S. Abdelsamie , Salwa M. Soliman , Jeremie Mortier , Gerhard Wolber , Mamdou ..., European Journal of Medicinal Chemistry, 2013

Publication date: November 2013 Source:European Journal of Medicinal Chemistry, Volume 69 Author(s): Shadia A. Galal , Ahmed S. Abdelsamie , Salwa M. Soliman , Jeremie Mortier , Gerhard Wolber , Mamdouh M. Ali , Harukuni Tokuda , Nobutaka Suzuki , Akira Lida , Raghda A. Ramadan , ...


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