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4,083 Newest Publications about the topic virusesrss
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05-Dec-2016 | Author(s): Anushka C. Galasiti Kankanamalage, Yunjeong Kim, Athri D. Rathnayake, Vishnu C. Damalanka, Pathum ..., European Journal of Medicinal Chemistry, 2016
Publication date: 27 January 2017 Source:European Journal of Medicinal Chemistry, Volume 126 Author(s): Anushka C. Galasiti Kankanamalage, Yunjeong Kim, Athri D. Rathnayake, Vishnu C. Damalanka, Pathum M. Weerawarna, Sean T. Doyle, Amer F. Alsoudi, D.M. Padmasankha ...
02-Dec-2016 | Benjamin M. Akiyama; Hannah M. Laurence; Aaron R. Massey; David A. Costantino; Xuping Xie; Yujiao Yang; Pei-Yong Shi ..., Science , 2016
The outbreak of Zika virus (ZIKV) and associated fetal microcephaly mandates efforts to understand the molecular processes of infection. Related flaviviruses produce noncoding subgenomic flaviviral RNAs (sfRNAs) that are linked to pathogenicity in fetal mice. These viruses make sfRNAs by ...
02-Dec-2016 | Kristen L. Mueller, Science , 2016
Vaccination Live attenuated vaccines can be very potent, but their potential to revert to their pathogenic form limits their use. In an attempt to get around this, Si et al. expanded the genetic code of influenza A viruses. They propagated viruses that were mutated to encode premature termination
02-Dec-2016 | Longlong Si; Huan Xu; Xueying Zhou; Ziwei Zhang; Zhenyu Tian; Yan Wang; Yiming Wu; Bo Zhang; Zhenlan Niu; Chuanling ..., Science , 2016
The conversion of life-threatening viruses into live but avirulent vaccines represents a revolution in vaccinology. In a proof-of-principle study, we expanded the genetic code of the genome of influenza A virus via a transgenic cell line containing orthogonal translation machinery. This generated ...
02-Dec-2016 | Julia Fahrenkamp-Uppenbrink, Science , 2016
Epidemiology Bats carry numerous viruses, such as rabies and Ebola, which they can transmit to humans. In a Perspective, Hayman highlights recent genetic studies showing that male vampire bats are key to rabies dispersal and transmission in Peru. Rabies is more often transmitted between related
02-Dec-2016 | Fardokht A. Abulwerdi; Matthew D. Shortridge; Joanna Sztuba-Solinska; Robert Wilson; Stuart F. J. Le Grice; Gabriele ..., Journal of Medicinal Chemistry, 2016
Small molecules that bind to RNA potently and specifically are relatively rare. The study of molecules that bind to the HIV-1 transactivation response (TAR) hairpin, a cis-acting HIV genomic element, has long been an important model system for the chemistry of targeting RNA. Here we report the ...
02-Dec-2016 | Karam El-Bayoumy; Kun-Ming Chen; Shang-Min Zhang; Yuan-Wan Sun; Shantu Amin; Gary Stoner; Joseph B. Guttenplan, Chemical Research in Toxicology, 2016
Worldwide, cancers of the oral cavity and pharynx comprise the sixth most common malignancies. Histologically, more than 90% of oral cancers are squamous cell carcinoma (SCC). Epidemiologic data strongly support the role of exogenous factors such as tobacco, alcohol, and human papilloma virus ...
01-Dec-2016 | Ronald A. Kohanski, Steven G. Deeks, Claudia Gravekamp, Jeffrey B. Halter, Kevin High, Arti Hurria, Rebecca Fuldner, ..., Annals of the New York Academy of Sciences, 2016
Aging is the major risk factor for both the development of chronic diseases and loss of functional capacity. Geroscience provides links among the biology of aging, the biology of disease, and the physiology of frailty, three fields where enormous progress has been made in the last few decades. ...
01-Dec-2016 | Chen, Shun ; Wang, Anqi ; Sun, Lipei ; Liu, Fei ; Wang, Mingshu ; Jia, Renyong ; Zhu, Dekang ; Liu, Mafeng ; Yang, Q ..., International Journal of Molecular Sciences, 2016
Goose parvovirus (GPV) and avian influenza virus subtype H9N2 are single-stranded DNA (ssDNA) and single-stranded RNA (ssRNA) viruses, respectively, both of which can spread in goslings and cause a significant economic loss. To explore the comprehensive transcriptome of GPV- or H9N2-infected ...
01-Dec-2016 | ;, Nature, 2016
Chernobyl's shield, dodo skeleton and HIV vaccines Nature 540, 7631 (2016). http://www.nature.com/doifinder/10.1038/540012a The week in science: 25 November–1 December 2016.