Smart Solutions for large Molecules

24-11-2010

Development and production of biopharmaceuticals is a growing segment of pharmaceutical industry. Therapeutic proteins include blood factors, thrombolytic agents, growth factors, interferons, interleukins, therapeutic enzymes and last but not least monoclonal antibodies. More than twenty ...

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16-11-2010

In recent years water-soluble polymers are gaining more and more interest in different applications. The molecular weight distribution of polymers is usually characterized by size exclusion chromatography (SEC) coupled with refractive index, viscometric or laser light scattering detection. ...

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22-09-2010

High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar ...

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27-11-2009

Ever since scientists work with proteins, polymers and particles, there has been an enormous demand to know their molar mass and physical size without making a priori assumptions about these molecules. This is because their properties can depend both on their size and chemical composition. ...

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16-11-2009

In today’s competitive skin care market, consumers look for a range of benefits, superior aesthetics and cost effectiveness. In response, formulators strive to create products that are multifunctional, easy to use and effective in small quantities. At the same time, the most successful ...

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05-11-2009

The AF4-MALS combined technique can serve as a routine method for polymer analysis and characterization. AF4 provides separation efficiency entirely comparable with traditionally used and so far dominating SEC. In addition, it yields superior separation of branched polymers, polymers ...

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03-09-2009

Rolling-element bearings are used for the precise guidance of moving parts. Frictional losses are extremely small because the bearings rest on rolling elements, enabling very heavy loads to be adsorbed. Rolling-element bearings may be lubricated with greases or oils depending on the point of ...

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16-06-2008

Polyethylene and Polypropylene are so-called Polyolefins. They are produced in large amounts every year. Depending on the process and catalyst used linear or branched polymers can be produced. In case of e. g. Polyethylene there are at least three polymer types: HDPE (High Density ...

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08-11-2006

Colloid emulsions in their native environment require particle size determination in high concentration since there are concerns about changes in sample morphology upon dilution eg break up of aggregates. For proteins and other samples with very low concentration and for weakly scattering ...

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"Triple Detection" in Gel Permeation Chromatography

11-11-2005

Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole ...

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