Smart Solutions for large Molecules

24-11-2010

Development and production of biopharmaceuticals is a growing segment of pharmaceutical industry. Therapeutic proteins include blood factors, thrombolytic agents, growth factors, interferons, interleukins, therapeutic enzymes and last but not least monoclonal antibodies. More than twenty ...

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16-11-2010

Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised ...

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22-09-2010

High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar ...

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Prof. Marc Spehr on the New Understanding of Olfactory Neurosensorics

20-09-2010

#img6121# In his novel “Perfume – the Story of a Murderer”, Patrick Süskind managed to put the power of odors into words better than anyone before him. It may be a fascinating idea, but no one will ever be able to create the perfect fragrance that makes a person irresistibly attractive. In ...

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27-11-2009

Ever since scientists work with proteins, polymers and particles, there has been an enormous demand to know their molar mass and physical size without making a priori assumptions about these molecules. This is because their properties can depend both on their size and chemical composition. ...

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09-11-2009

INTRODUCTION From the late 1980s commercial Dynamic Light Scattering (DLS) detectors started being used in commercial biophysical laboratories throughout the world. These instruments enabled size measurements of small volumes of proteins and other biomaterials in solution to be made, with ...

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15-09-2009

Antioxidants are able to neutralize Reactive Oxygen Species Antioxidant capacity of fruit juices determined with the ORAC assay in 96 and 384-well format MARS data analysis software with predefined templates for quick ORAC evaluation Introduction In all oxygen consuming cells, metabolism ...

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29-06-2007

Application 1 Fast method development and upscaling shown by the example of a root extrakt. Rotor volume 200 ml, flow rate: 10 ml/min, detection UV 254 nm, solvent system: hexane-ethylacetate-methanol-water Fig. 1Fig. 2 Fig. 3 Fig. 4 The analytical HPLC chromatogram (Fig.1) shows the ...

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07-02-2007

Dynamic Light Scattering (DLS) is an established technique in the field of protein crystallography. DLS is used to measure hydrodynamic sizes, polydispersities and aggregation effects of protein samples. These are important parameters for the crystallisation of proteins. DLS is also used in ...

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08-11-2006

Colloid emulsions in their native environment require particle size determination in high concentration since there are concerns about changes in sample morphology upon dilution eg break up of aggregates. For proteins and other samples with very low concentration and for weakly scattering ...

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