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22 Current white paper about the topic water

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Characterizing Biotherapeutics with HPLC

Smart Solutions for large Molecules

24-11-2010

As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. ...

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Increased productivity for downstream processing of biotherapeutics

16-11-2010

Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised ...

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Structural and Chemical 3D Imaging with AFM and Raman.

12-10-2010

In the Life Sciences and Bio-medical Research, the characterization of chemical compounds within cells or tissues is one of the most important and difficult tasks for researchers to perform. The development of pharmaceuticals such as drug delivery coatings or capsules also requires as much ...

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Size and element specific determination of Ag nanoparticles in consumer spray products using asymmetric flow field flow fractionation (AF4) coupled to ICPMS

10-09-2010

The use of nanoparticles in consumer products shows a tremendous increase over the past years. A study of the Woodrow Wilson International Centre for Scholars reported that between 2005 and today the number of products based on nanoparticles increased almost twentyfold from 54 to 1015. As active ...

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Particle sizing with static laser scattering

27-08-2010

When determining particle sizes a wide variety of techniques are used in which sieving may be the most popular. Sieving is a relatively simple technique, despite the fact that of course different instrumental approaches can be used. The main advantages of sieving are the low price of the ...

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Quality control of colorimetrically stained gels and blots

Comparison of 2 methods

17-03-2010

In the pharmaceutical and food industry, using a scanner-based system is more recommended than using a camera-based system for the acquisition, documentation and analysis of colorimetrically stained gels, blots and TLC samples. The combination of a scanner with a suitable control and analysis ...

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Automated Dynamic Light Scattering

09-11-2009

DLS analysis is a widely applied, non-invasive method for measuring the effective size of molecules in solution. This technique yields valuable information for the characterization of molecules and particles. It facilitates formerly laborious and time consuming measurements, e.g. screening for ...

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Asymmetric Flow Field Flow Fractionation (AF4) - A Powerful Method for Polymer Characterization

05-11-2009

The AF4-MALS combined technique can serve as a routine method for polymer analysis and characterization. AF4 provides separation efficiency entirely comparable with traditionally used and so far dominating SEC. In addition, it yields superior separation of branched polymers, polymers containing ...

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ORAC Assay Performed on the POLARstar Omega and PHERAstar FS microplate reader

15-09-2009

In all oxygen consuming cells, metabolism and oxidative stress generate several intermediates and byproducts that are collectively known as reactive oxygen species (ROS). ROS are necessary intermediates in the human body, but they are also involved in the aging process and in the development of ...

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Improvement of power generation efficiency of solar cells and evaluation by fluorescence spectroscopy

24-08-2009

The light in the high-radiance wavelength region of the solar spectrum is not utilized effectively by silicon crystal-based solar cell modules. "Fluorescent materials" convert the ultraviolet component in the sunlight into light in the longer wavelength region where this solar cell modules can ...

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