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4 Current white paper about the topic waterrss
Prof. Marc Spehr on the New Understanding of Olfactory Neurosensorics
In his novel "Perfume - the Story of a Murderer", Patrick Süskind managed to put the power of odors into words better than anyone before him. It may be a fascinating idea, but no one will ever be able to create the perfect fragrance that makes a person irresistibly attractive. In the animal world, on the other hand, olfactory signals are an essential element of social communication. Yet we are only just beginning to understand the complexities and functional differences of the sense of smell in mammals. Professor Marc Spehr is leading the Department of Chemosensation at RWTH Aachen University since 2009, where he is conducting research on the neuronal mechanisms of olfactory perception and signal processing using the mouse model. In his experiments, he and his team are trying to find out how substances for social interaction are perceived and how this perception generates a specific type of behavior...
DLS analysis is a widely applied, non-invasive method for measuring the effective size of molecules in solution. This technique yields valuable information for the characterization of molecules and particles. It facilitates formerly laborious and time consuming measurements, e.g. screening for aggregates or determining optimal crystallization conditions for proteins. The Wyatt Plate Reader is the instrument of choice for any application where molecular size, stability and aggregation are of interest. It reads industry standard microplates with up to 1536 samples automatically and temperature-controlled, if desired. The applications of the technique are wide ranging and include many of the fastest growing areas of research - proteins, biomaterials, liposomes and micelles as well as the established uses for particle sizing and aggregation detection. Conscious of the numerous characterization challenges in the area of drug delivery systems and therapeutic antibodies...
In all oxygen consuming cells, metabolism and oxidative stress generate several intermediates and byproducts that are collectively known as reactive oxygen species (ROS). ROS are necessary intermediates in the human body, but they are also involved in the aging process and in the development of many degenerative diseases, including cancer, heart disease, Alzheimer's and Parkinson's. Herein we describe the determination of the antioxidant capacity of different fruit juices using the ORAC assay; a standardized method that uses Trolox®, a water-soluble analogue of vitamin E, as a standard substance...
Dynamic Light Scattering (DLS) is an established technique in the field of protein crystallography. DLS is used to measure hydrodynamic sizes, polydispersities and aggregation effects of protein samples. These are important parameters for the crystallisation of proteins. DLS is also used in the nanotechnology research for the accurate and fast size measurement of nanoparticles made of different materials....