ABCB5
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ATP-binding cassette, sub-family B (MDR/TAP), member 5
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| Identifiers |
| Symbol |
ABCB5 |
| Entrez |
340273 |
| HUGO |
46 |
| RefSeq |
NM_178559 |
| UniProt |
Q2M3G0 |
| Other data |
| Locus |
Chr. 7 p14 |
ABCB5 [ATP-Binding Cassette Subfamily B (MDR/TAP) Member 5] is a human ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.
ABCB5 regulates skin progenitor cell fusion and mediates chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma.
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Membrane proteins, carrier proteins: membrane transport proteins |
| ABC-transporter |
A1, A2, A4, A12, B1, B2-3, B4, B5, B11, C1, C2, C4, C5, C6, C8, C8-9, C11, D1, D3, E1, G1, G2, G5, G8 |
| Solute carrier |
1A1-7, 1A1, 1A2, 1A3, 1A5, 2A1, 2A2, 2A3, 2A4, 3A1, 3A2, 4A1, 4A4, 4A7, 5A1-2, 5A5, 6A1, 6A2, 6A3, 6A8, 6A4, 7A5, 7A9, 8A1-3, 9A1, 9A3, 10A2, 11A1, 11A2, 11A3, 12A1-2, 12A3, 15A1, 17A5, 17A6-8, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 23A1, 23A2, 24A1-2, 24A5, 25A4-6, 25A8, 25A13, 25A15, 25A20, 26A2, 26A3, 26A4, 29A1, 29A2, 30A8, 31A1, 31A2, 34A1, 37A4, 39A4, 40A1, O1B1 |
| Monosaccharide |
GLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT8 |
| Other |
Amino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Karyopherin) |
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