Valofane: Encyclopedia of chemistry, analytics & pharmaceutics with 64,557 entries.

Valofane


Valofane
Systematic (IUPAC) name
N-carbamoyl-5-methyl-2-oxo-3-prop-2-enyloxolane-3-carboxamide
Identifiers
CAS number	3258-51-3
ATC code	?
PubChem	71122
Chemical data
Formula	C₁₀H₁₄N₂O₄
Mol. mass	226.229 g/mol
Synonyms	Valofan, Valofane
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Valofane is a sedative drug structurally related to the barbiturates^[1] and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.^[2]

References

^ Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.
^ Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.

v • d • e

Barbiturates (N01AF, N03AA, N05CA)

Allobarbital • Amobarbital • Aprobarbital • Alphenal • Barbexaclone • Barbital • Brallobarbital • Butabarbital • Butalbital • Butobarbital • Butallylonal • Crotylbarbital • Cyclobarbital • Cyclopal • Ethallobarbital • Febarbamate • Hexethal • Heptabarbital • Hexobarbital • Mephobarbital • Metharbital • Methohexital • Methylphenobarbital • Narcobarbital • Nealbarbital • Pentobarbital • Phenobarbital • Probarbital • Propallylonal • Proxibarbal • Proxibarbital • Reposal • Secbutabarbital • Secobarbital • Sigmodal • Talbutal • Thialbarbital • Thiamylal • Thiobarbital • Thiobutabarbital • Thiopental • Valofane • Vinbarbital • Vinylbital

Categories: Barbiturates | Sedatives

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Valofane". A list of authors is available in Wikipedia.

Encyclopedia of Chemistry

References