Ultimate "Pick & Decision Dispense" of Solid Compounds (true one-to-one; <100 μg - 100+ mg) more
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Sigma-Aldrich announced the acquisition of cheminformatics company, ChemNavigator .com, Incorporated, a provider of discovery research informatics software tools used for design, selection and procurement of chemical compound libraries. The acquisition links ChemNavigator's suite of virtual screenin more
Galapagos NV announced that it has completed the sale of its BioFocus DPI chemistry facility in San Diego to ChemVentures Pty Ltd, an Australian discovery research group. Financial terms were not disclosed. The San Diego facility currently employs 40 people and provides medicinal chemistry and cu more
ChemDiv, Inc. and Nerviano Medical Sciences (NervianoMS), Milano, Italy, announced an extension of their collaboration to an additional 2 year program. NervianoMS will use services of ChemDiv for building and enriching its portfolio of proprietary discovery chemical libraries. Such compound librarie more
The availability of high-quality screening compounds is of paramount importance for the discovery of innovative new medicines. Natural product (NP) frameworks can inspire the design of productive compound libraries. Here, we describe the design and synthesis of four compound libraries based on scaff more
Molecules, Vol. 23, Pages 775: PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds Molecules doi: 10.3390/molecules23040775 Authors: Giacomo Rossino Maria Raimondi Ma more
The advantages of performing reactions in continuous flow versus the classic batch processes render flow chemistry a suitable technique for library synthesis. Inspired by our recent work to create fluorine‐containing N‐heterocycles and by the potential of the urea group in drug design, we herewith more
Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of the art, replaced by the CD-ROM, and then by the USB drive. more