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Development of an Efficient Enantioselective Desymmetrization Strategy Using Recombinant Pig Liver Esterases


An economically significant process intensification for the efficient enzymatic synthesis of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid was achieved by a careful adaption of the reaction mode to minimize mass transfer limitations. (1S,2R)-1-(methoxycarbonyl) ...


abcr GmbH and Enzymicals AG deepen the cooperation


To make the delivery of catalogue products more effectively, the abcr GmbH will handle the entire ordering process of Enzymicals catalogue products. This includes the preparation of offers, order confirmations, shipping and billing. In addition to orders placed at Enzymicals, selected enzymes can ...


ComBioCryst – idea won 2. Prize in idea competition


The jointly developed idea ComBioCryst of working group Jan von Langermann at Univerity of Rostock and Enzymicals won the 2. prize in idea competition "Inspired- The ideas competition. In MV." In category “Researchers/Alumni”. ComBioCryst describe a new method for preparing amines in ...


Enzymicals and abcr cooperate

The Special chemical manufacturers want to make use of synergies


The biotechnology company Enzymicals AG, based in Greifswald, and the Karlsruhe-based abcr GmbH are intensifying their collaboration in catalogue business. The two internationally active companies have now entered into an agreement for a global trade relationship. Each company benefits from the ...


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Biocatalysis gives access to novel substance classes and elusive species

Novel Manich catalysts and bicyclic carboxylic acid esters synthesised


The application of Enzymicals recombinant pig liver isoenzymes (rPLE) enables the synthesis of novel, optical pure diastereomers of substituted proline, which shows activity as anti-Mannich catalyst. Additionally, rPLE is the key for successful production of a previously unavailable bicyclic ...


Acrylonitrile from renewable raw materials

EnzymicalS and Dralon to develop biocatalytic synthesis route


Biocatalytic produced acrylonitrile is of great industrial interest to the "CO2 footprint" of polyacrylonitrile (PAN) fiber production. To address this, the main component for the production of PAN fibers, acrylonitrile, will be completely synthesized from renewable resources. The objective of ...


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Dr. Henrike Brundiek ist the new Head of R&D at Enzymicals AG


Dr. Brundiek is a long-term employee of Enzymicals AG and takes over the scientific management of the company from now on. The former CSO, Dr. Rainer Wardenga, steps down from the managing board due to a longer-term parental leave. This decision was made by mutual agreement between the bodies of ...


Enzymicals AG is a new 4chiral member


Enzymicals has been a member of the network 4chiral since 28.03.2017. With the slogan "Our core competence in organic synthesis", the network is conducting research and development projects in the field of organic synthesis. Enzymicals is now expanding the possibilities of the network by its ...


€ 1.2 Million in EU Project Funding for Enzymicals


Enzymicals is a consortium partner in three projects of the H2020-funding period. With these projects a total of € 1.2 million grants were procured for Enzymicals. The company thus has the opportunity to focus more on the scale-up and piloting of biocatalytic processes, on developing new products ...


Enzymicals AG Acquires Proprietary Rights on Pig Liver Esterases (PLE) from Evonik AG


The Enzymicals AG gained proprietary rights for the well-known recombinant pig liver esterases (PLE) from Evonik AG in Hanau. The intellectual property (IP) covers a range of PLE isoenzymes for hydrolysis of several compounds such as esters of secondary and tertiary alcohols, lactones and ...


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