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Squid tissues and chemistry combine for versatile hydrogels

The natural abilities of squid tissues and the creativity of chemists combine to take hydrogel research in new directions


Researchers at Hokkaido University in Japan have combined natural squid tissues with synthetic polymers to develop a strong and versatile hydrogel that mimics many of the unique properties of biological tissues. Hydrogels are polymer networks containing large quantities of water, and are being ...


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Automated chemical reaction prediction: Now in stereo

Automated reaction path search method predicts accurate stereochemistry of pericyclic reactions using only target molecule structure


Researchers at the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) have demonstrated the expanded use of a computational method called the Artificial Force Induced Reaction (AFIR) method, predicting pericyclic reactions with accurate stereoselectivity based only on information ...


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Simplified process shines light on new catalyst opportunities


Theory-guided development of an easier, more versatile process for synthesizing unsymmetric ligands provides new avenues of exploration in transitional metal catalysis. Researchers at the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) have discovered the key to synthesizing a ...


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Linked lanthanides shine light on field of crystal engineering

Rare earth metals, when linked, can act as a conduit for energy flow, and show promise for the development of novel materials


Scientists have connected two soft crystals and observed energy transfer between them—a finding that could lead to the development of sophisticated, responsive materials. The study, by scientists at Hokkaido University in Japan, was published in the journal Nature Communications. Soft crystals ...


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Efficient, stable, and eco-friendly thermoelectric material discovered


Waste heat is a very promising source of energy conservation and reuse, by means of converting this heat into electricity—a process called thermoelectric conversion. Commercially available thermoelectric conversion devices are synthesized using rare metals. While these are quite efficient, they ...


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Hitting rewind to predict multi-step chemical reactions

Researchers overcome computational limitations to predict the starting materials of multi-step reactions using only information about the target product molecule


Have you ever only caught the end of a TV show and wondered how the story progressed to that ending? In a similar way, chemists often have a desired molecule in mind and wonder what kind of reaction could produce it. Researchers in the Maeda Group at the Institute for Chemical Reaction Design and ...


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Chemical reaction design goes virtual

Researchers aim to streamline the time- and resource-intensive process of screening ligands during catalyst design by using virtual ligands


Researchers at the Institute for Chemical Reaction Design and Discovery and Hokkaido University have developed a virtual ligand-assisted (VLA) screening method, which could drastically reduce the amount of trial and error required in the lab during transition metal catalyst development. The ...


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CO₂ recycling and efficient drug development – tackling two problems with one reaction

Work marks an especially large breakthrough, since CO₂ is used to carry out a traditionally difficult type of transformation with unprecedented efficiency


Using electricity, a new method offers the possibility of recycling CO2 while also performing a notoriously difficult reaction, producing compounds potentially useful for drug development. Scientists at the Institute for Chemical Reaction Design and Discovery (ICReDD) in Hokkaido University have ...


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New, highly efficient catalyst for propylene production

Innovative catalyst for the synthesis of propylene has potential benefits for the chemical industry and carbon recycling


Propylene is a colourless, flammable hydrocarbon gas that is an important raw material for the production of a variety of petrochemicals. Due to increasing demand and limited global supply, there is a strong need to develop new, efficient technologies for its production. Researchers at Hokkaido ...


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A new tool to create chemical complexity from fatty acids

A new catalyst design enables unprecedented control over the modification of fatty acid derivatives that opens the door to creating useful substances in a green and efficient manner


Hokkaido University WPI-ICReDD researchers developed a modular catalyst that can accurately modify fatty acid derivatives in a hitherto inaccessible position. This enables the efficient production of valuable compounds from a renewable bioresource, whereas before we had to either rely on ...


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