Rapid synthesis towards optically active alpha-aminocarbonyl therapeutics
New catalytic asymmetric reaction directly installs amines into carbonyl compounds
24-Nov-2016 -
A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst. This unprecedented method leads to the rapid formation of optically active (chiral) α-aminocarbonyls, which are ...
acidification
alpha-aminocarbonyls
amines
+10