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19 Current news about the topic natural products

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On our way to the bio-economy: High-performance biocatalyst discovered

Future applications primarily in the production of active pharmaceutical ingredients, but also in the synthesis of fine chemicals expected

22-May-2020

In the bioeconomy, biotechnological processes are replacing processes that rely on fossil resources. Microorganisms and enzymes are being used in targeted fashion as biocatalysts for industrial production. Researchers at the University of Bayreuth have now discovered an enzyme that offers great ...

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Determining the atomic structure of natural products more rapidly and accurately

23-Jan-2020

Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry. This can be a major challenge, particularly when the molecules cannot be crystallized and contain only few hydrogen atoms. A new NMR-based ...

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A new strategy for the synthesis of complex natural products

11-Oct-2019

Chemists from the University of Basel have succeeded in synthesizing two complex natural products from the group of dithiodiketopiperazines (DTPs). For this, they employed a new strategy based on “C-H bond activation,” resulting in a short and high yielding route. In the of the Journal of the ...

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A molecular "Trojan Horse"

28-Aug-2019

The research group of Nuno Maulide from the Faculty of Chemistry of the University of Vienna has, in cooperation with the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, achieved the synthesis of a potential immunosuppressive agent by modification of a naturally ...

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Fungus produces highly effective surfactant

26-Jun-2019

Mortierella alpina lives in the soil and likes to keep cool. This fungus, which belongs to the zygomycetes, grows best at temperatures of 10 to 15°C and occurs mainly in alpine or arctic habitats. In biotechnology, the fungus has been used for the large-scale production of polyunsaturated fatty ...

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Phenyl addition made a poison useful for a chemical reaction in catalysis

20-Nov-2018

Scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, have discovered that a catalyst poison, which deactivates homogeneous catalysts, can be "reborn" as an efficient ligand by introduction of a substituent, in chemical reactions. This finding is of service to expand the ...

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Best of both worlds: Combining two skeleton-building chemical reactions

13-Aug-2018

Scripps Research scientists have developed a powerful new strategy for synthesizing molecular skeletons of chemicals used in drugs and other important products, a technique that provides unprecedented flexibility and control over chemical synthesis. The method, which combines two chemical ...

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SMART: Facial recognition for molecular structures

Paradigm shift in interpretation of NMR spectra

09-Nov-2017

An interdisciplinary team of researchers at the University of California San Diego has developed a method to identify the molecular structures of natural products that is significantly faster and more accurate than existing methods. The method works like facial recognition for molecular ...

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Indestructible virus yields secret to creating incredibly durable materials

20-Jul-2017

It's like the Superman of viruses, astonishingly tough and able to survive in an environment that would dissolve flesh and bone. And now scientists have unlocked the secrets of its indestructibility, potentially allowing them to harness its remarkable properties to create super-durable materials ...

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Figuring out the 3-D shape of molecules with a push of a button

21-Jun-2017

An international team of researchers led by Carnegie Mellon University chemist Roberto R. Gil and Universidade Federal de Pernambuco chemist Armando Navarro-Vázquez has developed a program that automates the process of figuring out a molecule's three-dimensional structure. The technique ...

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