Pick & Decision Dispense

Step Change in Compound Management

SWILE DISPENSING SOLUTIONS

Pharmaceutical industry faces the increased demand for innovative medicines against various diseases. In this regard, the compound library in pharmaceutical industry is the most valuable asset. However, the compound distribution from the library into the screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks.

The SWILE technology is the first fully automated true one-to-one gravimetric "pick & decision dispense" of compounds. The scheme at the bottom of this page displays the simplified SWILE workflow including a precision "pick & decision dispense" step. The technology backbone is following Chemspeed’s proprietary overhead gravimetric dispensing tool design in combination with a second analytical on-deck-balance.

Dispensing Characteristics

  • Revolutionary accuracy & precision due to decision dispensing.
  • Dispensing range from <100 μg to 100 mg with +/- 10 μg resolution.
  • No cross-contamination.
  • No dead volume.
  • Unattended operation.
  • Fully inert (glass).

In order to exclude any risk of cross-contamination disposable glass tips are used which are stored and provided by a SWIN dispenser.

The SWINS are available in different sizes (diameter) and can be adjusted according to the desired target amount to be dispensed. Additionally, a tilt / shake rack is used which is loosening up and tilting the powder prior to the pick-up.

FLEX SWILE SOLUTIONS

  • Proprietary robotic tool exchange interface.
  • Ventilated hood for safety and conditioned operation, trolley.
  • Optimized footprint (3x3 ft, 90x90 cm) versus capacity - all while reducing costs and maximizing return on investment.
  • Application programming interface for e.g. LIMS, ELN integration.
  • SWILE Robotic Tool can be combined with other tools to accommodate multiple workflows.
  • On-deck balance, tilt / shake rack, barcode reader, multigripper.
  • AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface to DoE and data analysis.


AUTOSUITE SOFTWARE

The intuitive and easy to use software supports the fully unattended production of screening assays from the pharmaceutical compound library.

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