Nanoparticle size & zeta potential using dynamic and electrophoretic light scattering (DLS, ELS)

Malvern Panalytical’s Zetasizer instruments are the world’s most widely-used systems for nanoparticle, colloid and protein size and charge measurements.

Zetasizer instruments are used across many industry sectors worldwide, delivering value in the control and optimization of processes, and the improvement of product quality, stability and performance. They are ubiquitous in academic settings, indispensable in a wealth of application spaces and referenced in tens of thousands of peer-reviewed publications.

Key applications:

• Bioscience and Biopharmaceuticals
• Paints, Inks and Coatings
• Nanomaterials
• Food and Drinks
• Pharmaceuticals and Drug Delivery
• Academia
• Consumer Products

The new Zetasizer Advance range with Zetasizer Pro, Zetasizer Ultra and Zetasizer Lab systems offers two types of light scattering technology as standard: dynamic light scattering (DLS) and electrophoretic light scattering (ELS).

Each model is available in two variants: a Blue Label version for routine sample investigation, and a Red Label version for use with more challenging samples.

The Zetasizer Ultra is the ultimate companion for fast yet accurate particle and molecule sizing, particle charge and particle concentration measurements, and represents the most intelligent and flexible instrument in the Zetasizer range. This powerful system has the unique capacity to perform calibration-free particle concentration measurements with ease, even deep into the nano size range.

Alongside Malvern Panalytical’s NIBS (Non-Invasive Back-Scatter) technology, the Zetasizer Ultra offers Multi-Angle Dynamic Light Scattering (MADLS^®). This groundbreaking technique provides high resolution angle-independent size measurements, meaning no more worry about missing particles in your sample. With MADLS, you can be sure that all angles are simultaneously covered.

Pushing the upper analytical size range higher than ever before, the Zetasizer Ultra is designed to provide data you can trust to help you make those important decisions to improve your products and processes. Despite its unique capabilities, the Zetasizer Ultra’s speed and ease-of-use are uncompromised, making it by far the most advanced and powerful light scattering system available.

The Zetasizer Pro is a robust and versatile solution for routine laboratory measurements of molecular size, particle size, electrophoretic mobility and zeta potential. Size measurements can now be performed more than twice as quickly, compared to previous models, accelerating sample throughput and freeing up operator and system time for other tasks.

Our entry-level model, the Zetasizer Lab, utilizes 90˚ measurements to generate high quality particle size and zeta potential data, especially when measuring larger-sized particles.

The ZS Xplorer software is designed to simplify and automate even complex analysis, allowing challenging measurements to be completed without expert knowledge. Its unique sample-centric workflow delivers the ultimate in usability and flexibility, meaning it’s faster and easier than ever to get from sample input to result output. A common challenge with light scattering is dust contamination – this can now be intelligently identified and filtered from the data. It’s also immediately apparent if results aren’t quite as expected and need a little more attention. Integrated deep learning empowered data quality guidance offers instant feedback, flagging any queries and providing actionable advice on how to improve lower quality data.

The three systems enable robust and versatile measurement of particle and molecular size and electrophoretic mobility and zeta potential of nanoparticles. Even novice users will produce the highest-quality measurements, thanks to the intuitive interface and the deep learning empowered data quality advice system that highlights issues and provides advice on how to overcome them.

Customer testimonials:

“The Zetasizer is an excellent instrument for the study of particle size and charge. It is quick and easy to use and reliable in terms of the repeatability of results. I cannot imagine trying to complete my Nano emulsion project without it.”

“The Zetasizer is such an easy system to use for the analysis of low volumes of nanoparticles in various dispersants for size and zeta potential measurements. The various cells are easy to use and cover all applications. The auto-titration unit is also very efficient at producing pH, isoelectric and titration results. Malvern Panalytical customer support is just an email away when help or service is needed. This is one of the most used and valued particle analyzers in our lab!”