The AZURA Cannabis Purifier is a dedicated preparative system to purify cannabinoids from cannabis extracts. The HPLC layout consists of a pump with ternary LPG valve block and a HPLC docking station equipped with a variable wavelength UV detector, an injection valve and a fractionation valve for 11 fractions and waste. The system is designed for method development and small volumes of sample in a flow rate range between 10 to 80 ml/min at maximum 400 bar. The system is controlled by the intuitive and touch-optimized Mobile Control, which is installed on a tablet. The software includes a function for threshold-based fractionation. Depending on the value of the detector signal the target substances/peaks are collected automatically. The purification of CBD from a cannabinoid oil is shown exemplarily.
Due to its modular design, the system can be easily upscaled to higher flow rates by simply replacing the pump head, valves, flow cell and capillaries. The main devices do not need to be replaced. The modules of the HPLC docking station and the valves are exchanged within minutes.