KNAUER has developed the RNA Purifier, a preparative HPLC system for batch purification of RNA.
The purification is carried out at elevated temperatures to denature the RNA, simplifying its structural diversity and allowing successful separation. Under reversed-phase separation conditions, RNase is effectively deactivated, preventing RNA cleavage. The system with a precise gradient pump, UV detection and temperature control supports your RNA research by reliably purifying your valuable samples from by-products.
The system can be optimally used at flow rates between 10 and 80 ml/min at max. 400 bar and can collect the fractions according to peak signal. An eluent heater and a column heating sleeve ensure exact temperatures even at high flow rates. The temperatures measured at the column inlet and outlet are monitored by the software.
This configuration can be used, for example, to effectively purify RNA therapeutic candidates for combating SARS-CoV-2.
System for lipid nanoparticle formulation research
Determine conditions for optimal API encapsulation results ✓ Scalable results: can be transfered to large-scale KNAUER IJM equipment ✓ Produce amounts enough for in vitro studies and small-scale production ✓ more
Flexible LC platform for the purification of active ingredients and other valuable substances
Automate purification procedures to save time and increase reproducibility ✓ Re-inject fractions separated by LC with high precision ✓ High-throughput fractionation for research applications ✓ more
Simplify your complex analytical chromatography tasks
Automates complex chromatography tasks through high flexibility ✓ Loss-free sample feed and lowest carry-over values ✓ Ideal autosampler for LC MS/MS or GC MS/MS ✓ more
Separate Molecules Continuously Using SMB Chromatography
Simulated moving bed chromatography (SMB) is a process chromatography technique that allows you to continuously separate the molecules from binary mixtures into two fractions. Chiral compounds, carbohydrates and cell culture products can be separated much more effectively than with batch HP ... more
KNAUER celebrates 60th anniversary and awards science prize to a young researcher
The Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER Wissenschaftliche Geräte GmbH celebrated its sixtieth company anniversary with a big party on July 1, 2022 under the motto "Science with Passion". For this occasion, the company had invited about 100 guests f ... more
KNAUER is partnering with ModuVision
This year KNAUER is celebrating the 60th company anniversary and there is more reason for joy. The management is excited to announce that KNAUER has just taken an important step. They aquired a company based in Vlissingen in the Netherlands. This hightech company is an expert in the field o ... more
KNAUER celebrates 60 years of science with new technology, a science award and more
The Berlin-based manufacturer of high-tech laboratory instruments, KNAUER Wissenschaftliche Geräte GmbH, is celebrating its 60th anniversary this year and has some special promotions to celebrate throughout the year. 60 years – it’s not so extraordinary for a person to reach this age but fo ... more
How to save 80% costs of continuous small molecule and biomolecule purification
Simulated moving bed chromatography (SMBC) is an HPLC technique that continuously separates substance mixtures and extracts them into two fractions more
Automated GPC Cleanup – sample preparation from challenging matrices
Improve reproducibility and quality of your analysis through automated sample preparation more
KNAUER Wissenschaftliche Geräte GmbH
KNAUER is a medium-sized, family-owned company that has been active in the service of science since 1962. We develop and manufacture instruments of the highest quality for systems and components used in liquid chromatography: - Analytical HPLC / UHPLC - Preparative HPLC - Fast Protein ... more
Dosing Pumps - Achieving Precise, High-Pressure Dosing
KNAUER's high-pressure dosing pumps are compact, versatile and reliable. In this webinar we will be explore the technology behind our pumps and taking a closer look at the applications they can be used in - such as polymer production, microfluidics and the dosing of aggressive substances.Ou ... more
