Your Samples Are Complex. Separating Them Shouldn't Be

Vanquish UHPLC system – the new standard in high-end UHPLC

The Vanquish UHPLC System…
Designed with innovative technology and fine detail, the Thermo Scientific™ Vanquish™ UHPLC System delivers a new standard in high-end UHPLC—more results with better separations and easier interaction simultaneously, without compromise.

Conceived for the uniquely efficient 1.5 µm solid core particle Thermo Scientific™ Accucore™ Vanquish™ C18 UHPLC column, this fully integrated and biocompatible system features high sample capacity for high-throughput workflows, intelligent sample pre-compression, industry-leading pumping performance, amazingly low S/N and linearity, two-mode thermostatting, active pre-heating, and much more in a system that's driven by the gold-standard in CDS software.

…Handles the sample with more accuracy
The Vanquish UHPLC system combines maximum injection precision with huge sample capacity and high-throughput capabilities. Out of the box, the Vanquish system comes with a vial capacity of 216 samples (12 mm OD vials). Increase to 8832 sample capacity (23 well plates) by adding the optional Thermo Scientific™ Vanquish™ Charger.

  • Unsurpassed sample dosage precision
  • Intelligent sample pre-compression for unmatched retention time precision and improved ruggedness
  • Innovative air stream cooling for maximum sample integrity
  • Automated workflows with barcode reading

…Drives the separation with more power
The Vanquish UHPLC system was developed to offer more pressure capabilities than ever before, without any tradeoff on durability or robustness. It offers the perfect harmonization of pumping control and smart fluidics for lowest gradient delays and exceptional gradient profile formation. Together with the intelligent sample pre-compression, the Vanquish UHPLC system provides unmatched retention time reproducibility and lowest baseline noise for highest detection sensitivity.

  • Higher pump performance: 1500 bar (22,000 psi) of pump pressure at flow rates up to 5 mL/min
  • Industry-leading flow and gradient precision
  • More flexibility by 2x3 solvent channels for up to nine different solvent combinations without stopping your experiment to replace solvents

…Controls the separation with more confidence
Temperature rules retention, selectivity and efficiency in chromatography. The Vanquish UHPLC system offers the unique choice between two thermostatting capabilities - boosted separation speed and resolution in still air mode, seamless method transfer by forced air mode. Avoid performance loss from temperature mismatch effects using the active pre-heating to ensure solvent entering the column will flawlessly meet the column temperature.

  • Two thermostatting modes: still air and forced air
  • Temperature range from 5°C to 120°C
  • Perfect alignment between eluent and column temperature by active eluent pre-heating

...Detects the analyte with more sensitivity
The Vanquish UHPLC system offers diode-array detection with a wide linear range and industry-leading signal-to-noise performance, even beyond the capabilities of variable wavelength detectors. The Thermo Scientific™ LightPipe™ technology with low-dispersion 10 mm and 60 mm flow cells, the simultaneous acquisition of up to ten signal channels and a spectrum 3D field at 200 Hz, programmable optical slit widths for best spectral resolution, and lowest baseline drift provide you with an unmatched detection experience.

  • Linear up to 3000 mAU
  • Noise levels down to ±3 μAU
  • Lowest dispersion and baseline noise

Easy and reliable tool-free connections
Enjoy tool-free maintenance and easy and reliable sealing mechanism of check valves and other connections with the Thermo Scientific™ Viper™ Fingertight Fittings.

Driven by gold-standard CDS Software
Control and monitor your experiment with the award-winning Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software. Add the convenience of controlling and monitoring your experiment directly from a tablet using the Chromeleon App, which will be available on all major mobile platforms.

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