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Warfarin genotyping with hybridization-induced aggregation on a poly(ethylene terephthalate) microdevice

Warfarin, a commonly prescribed oral anticoagulant, is burdened by a narrow therapeutic index and high inter-individual variability in response, making it the second leading cause of drug-related emergency room visits. Since genetic factors contribute significantly to warfarin sensitivity, a genotype-guided dosing

Authors:   Hillary S. Sloane; Morgan B. Carter; Alexa E. C. Cecil; Delphine Le Roux; Daniel L. Mills; James P. Landers
Journal:   Analyst
DOI:   10.1039/C6AN02325H
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