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Auf der Grundlage des aktuellen Wissenstands zu den physikalischen Eigenschaften und den biologischen Wirkungen von Gewebekompatiblen Atmosphärendruckplasmen (Tissue Tolerable Plasma, TTP) werden die Perspektiven der Plasmamedizin diskutiert. Für folgende Möglichkeiten der medizinischen Anwendung von TTP werden derzeit die Grundlagen in interdisziplinärer Forschung erarbeitet: Prävention und/oder Therapie von Erkrankungen mit den Schwerpunkten chronische Wunden, infektiöse Haut- und Schleimhauterkrankungen, lokalisierte Tumoren, GewebeabtragungHemmung und/oder Elimination von Biofilmen: Verhinderung der Biofilmentwicklung auf in den Menschen eingebrachte Materialien durch Oberflächenbehandlung und/oder plasmagesteuerte Auftragung antimikrobiell wirksamer Schichten mit der Funktion eines "Drug Delivery Systems[rdquor] (Implantate, Kontaktlinse, Stents usw.) sowie Bekämpfung von Biofilmen auf der Körperoberfläche (chronische Wunde, Zahnoberfläche, Prothese)Förderung der Penetration topisch applizierter Arzneimittel mit verbessertem TherapieergebnisEinsatz für veterinärmedizinische IndikationenVerbesserte Reinigungsleistung im Aufbereitungsprozess von Medizinprodukten durch Oberflächenveränderung.
| Authors: | Kramer, Axel; Assadian, Ojan; Below, H.; Bender, Claudia; Hammann, Aylin; Hartmann, Bernd; Hübner, Nils‐Olaf; Kocher, Thomas; Lademann, Jürgen; Matthes, Rutger; Koban, Ina; Weltmann, Klaus‐Dieter | |
| Journal: | Vakuum in Forschung und Praxis | |
| Volume: | 22 | |
| edition: | 2 | |
| Year: | 2010 | |
| Pages: | 33 | |
| DOI: | 10.1002/vipr.201000415 | |
| Publication date: | 01-Apr-2010 |
The unfolding landscape of the congenital myasthenic syndromes
Abstract Congenital myasthenic syndromes (CMS) are heterogeneous disorders in which the safety margin of neuromuscular transmission is impaired by one or more specific mechanisms. Since the advent of next‐generation sequencing methods, the discovery of novel CMS targets and phenotypes ha ... more
Passive transfer models of myasthenia gravis with muscle‐specific kinase antibodies
Abstract Myasthenia gravis (MG) with antibodies to muscle‐specific kinase (MuSK) is characterized by fluctuating fatigable weakness. In MuSK MG, involvement of bulbar muscles, neck, and shoulder and respiratory weakness are more prominent than in acetylcholine receptor (AChR) MG. MuSK au ... more
Abstract Because of the failure of many promising therapeutics identified in preclinical evaluation, funding sources have established guidelines for increased rigor in animal evaluations. The myasthenia gravis (MG) community of scientists has developed guidelines for preclinical assessme ... more
Smart skin made of recyclable materials may transform medicine and robotics
Smart skin that can respond to external stimuli could have important applications in medicine and robotics. Using only items found in a typical household, researchers have created multi-sensor artificial skin that's capable of sensing pressure, temperature, humidity, proximity, pH, and air ... more
How mercury contamination affects reptiles in the Amazon basin
Mercury contamination in water and on land is of worldwide concern due to its toxic effects on ecosystems and human health. Mercury toxicity is of particular concern to reptiles because they are currently experiencing population declines. Also, reptiles are ideal indicators of mercury conta ... more
Bioengineers Succeed in Producing Plastic Without the use of Fossil Fuels
A team of pioneering South Korean scientists have succeeded in producing the polymers used for everyday plastics through bioengineering, rather than through the use of fossil fuel based chemicals. This groundbreaking research, which may now allow for the production of environmentally consci ... more
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