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High Throughput Mechanochemistry: Application to Parallel Synthesis of Benzoxazines

We describe herein an unprecedented mechanochemical “parallel synthesis” of 3,4-dihydro-2H-benzo[e][1,3]oxazine derivatives via a one pot three component reaction. The new milling system uses a multiposition jar (variable sizes are possible), allowing to process up to 12 samples simultaneously, leading to a

Authors:   Katia Martina; Laura Rotolo; Andrea Porcheddu; Francesco Delogu; Stephen Bysouth; Giancarlo Cravotto; Evelina Colacino
Journal:   Chemical Communication
DOI:   10.1039/C7CC07758K
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