Circularly Polarized Luminescence Appeared from Complete Inorganic Materials Encapsulating Guest Lanthanide Oxides in Host Chiral Silica
Recently, circularly polarized luminescence (CPL)‐active systems have become a very hot and interesting subject in chirality‐ and optics‐related areas. The CPL‐active systems are usually available by two approaches: combining covalently a luminescent centre to chiral motif or associating the guest of luminescent probe to a chiral host. However, all the chiral components in CPL materials were organics although the parts of luminescent were alternative as organics or inorganics. Herein, we proposed the first totally inorganic CPL‐active system by "luminescent guest ‐ chiral host" strategy. Typically, luminescent sub‐10 nm lanthanide oxides (Eu2O3 or Tb2O3) nanoparticles ("guest") were encapsulated on chiral non‐helical SiO2 nanofibres ("host") via the calcination (at 900 oC) of chiral SiO2 hybrids nanofibres of trapping Eu3+ (or Tb3+). These lanthanide oxides showed circular dichroism (CD) optical activity in the ultraviolet wavelength and CPL signals around at 615 nm for Eu3+ or 545 nm for Tb3+. This work would be very instructive to design inorganics‐based CPL‐active systems by incorporation of various luminescent guests in chiral inorganic hosts.
Congenital myasthenic syndromes (CMS) are heterogeneous disorders in which the safety margin of neuromuscular transmission is impaired by one or more specific mechanisms. Since the advent of next‐generation sequencing methods, the discovery of novel CMS targets and phenotypes ha ... more
Myasthenia gravis (MG) with antibodies to muscle‐specific kinase (MuSK) is characterized by fluctuating fatigable weakness. In MuSK MG, involvement of bulbar muscles, neck, and shoulder and respiratory weakness are more prominent than in acetylcholine receptor (AChR) MG. MuSK au ... more
Because of the failure of many promising therapeutics identified in preclinical evaluation, funding sources have established guidelines for increased rigor in animal evaluations. The myasthenia gravis (MG) community of scientists has developed guidelines for preclinical assessme ... more
Smart skin that can respond to external stimuli could have important applications in medicine and robotics. Using only items found in a typical household, researchers have created multi-sensor artificial skin that's capable of sensing pressure, temperature, humidity, proximity, pH, and air ... more
Mercury contamination in water and on land is of worldwide concern due to its toxic effects on ecosystems and human health. Mercury toxicity is of particular concern to reptiles because they are currently experiencing population declines. Also, reptiles are ideal indicators of mercury conta ... more
A team of pioneering South Korean scientists have succeeded in producing the polymers used for everyday plastics through bioengineering, rather than through the use of fossil fuel based chemicals. This groundbreaking research, which may now allow for the production of environmentally consci ... more