My watch list
my.chemeurope.com  
Login  

Characterization and identification of novel antidiabetic and anti-obesity peptides from camel milk protein hydrolysates

Publication date:

1 September 2018


Source:Food Chemistry, Volume 259

Author(s): Priti Mudgil, Hina Kamal, Gan Chee Yuen, Sajid Maqsood

In-vitro inhibitory properties of peptides released from camel milk proteins against dipeptidyl peptidase-IV (DPP-IV), porcine pancreatic α-amylase (PPA), and porcine pancreatic lipase (PPL) were studied. Results revealed that upon hydrolysis by different enzymes, camel milk proteins displayed dramatic increase in inhibition of DPP-IV and PPL, but slight improvement in PPA inhibition was noticed. Peptide sequencing revealed a total of 20 and 3 peptides for A9 and B9 hydrolysates respectively, obtained the score of 0.8 or more on peptide ranker and were categorized as potential DPP-IV inhibitory peptides. KDLWDDFKGL in A9 and MPSKPPLL in B9 were identified as most potent PPA inhibitory peptide. For PPL inhibition only 7 and 2 peptides qualified as PPL inhibitory peptides from hydrolysates A9 and B9, respectively. The present study report for the first time PPA and PPL inhibitory and only second for DPP-IV inhibitory potential of protein hydrolysates from camel milk.





Authors:   Author(s): Priti Mudgil, Hina Kamal, Gan Chee Yuen, Sajid Maqsood
Journal:   Food Chemistry
Volume:   259
Year:   2018
Pages:   46
DOI:   10.1016/j.foodchem.2018.03.082
Publication date:   15-Apr-2018
Facts, background information, dossiers
  • peptides
  • milk
  • Total
More about Elsevier
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE