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Molecules, Vol. 23, Pages 877: An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease

Molecules, Vol. 23, Pages 877: An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease

Molecules doi: 10.3390/molecules23040877

Authors: Priscila Silva Figueiredo Aline Inada Melina Ribeiro Fernandes Daniela Granja Arakaki Karine Freitas Rita Avellaneda Guimarães Valter Aragão do Nascimento Priscila Aiko Hiane

Metabolic syndrome (MetS) is characterized by interconnected factors related to metabolic disturbances, and is directly related to the occurrence of some diseases such as cardiovascular diseases and type 2 diabetes. MetS is described as one or both of insulin resistance and visceral adiposity, considered the initial causes of abnormalities that include hyperglycemia, elevated blood pressure, dyslipidemia, elevated inflammatory markers, and prothrombotic state, as well as polycystic ovarian syndrome in women. Other than in MetS, visceral adiposity and the pro-inflammatory state are also key in the development of non-alcoholic fatty liver disease (NAFLD), which is the most prevalent chronic liver disease in modern society. Both MetS and NAFLD are related to diet and lifestyle, and their treatment may be influenced by dietary pattern changes and the use of certain dietary supplements. This study aimed to review the role of food ingredients and supplements in the management of MetS and NAFLD specifically in human clinical trials. Moreover, bioactive compounds and polyunsaturated fatty acids (PUFAs) may be used as strategies for preventing the onset of and treatment of metabolic disorders, such as MetS and NAFLD, improving the inflammatory state and other comorbidities, such as obesity, dyslipidemias, and cardiovascular diseases (CVD).

Authors:   Silva Figueiredo, Priscila ; Inada, Aline Carla; Ribeiro Fernandes, Melina ; Granja Arakaki, Daniela ; Freitas, Karine de Cássia; Avellaneda Guimarães, Rita de Cássia; Aragão do Nascimento, Valter ; Aiko Hiane, Priscila
Journal:   Molecules
Volume:   23
edition:   4
Year:   2018
Pages:   877
DOI:   10.3390/molecules23040877
Publication date:   11-Apr-2018
Facts, background information, dossiers
  • molecules
  • dietary supplements
  • clinical trials
  • cardiovascular diseases
  • blood pressure
  • ALine
More about Molecular Diversity Preservation International
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