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Concomitant desalting and concentration of neuropeptides on a donut-shaped surface pattern for MALDI mass spectrometry

We demonstrate that a donut-shaped surface pattern consisting of a central hydrophobic region and a surrounding hydrophilic region simultaneously concentrates and desalts a solution of neuropeptides with a high salt content. Our approach greatly simplifies the sample preparation process for MALDI mass spectrometry.

Authors:   Sook Yoon; Sanghwan Park; Min Sun Kim; Chang Young Lee
Journal:   Chemical Communication
DOI:   10.1039/C8CC02168F
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  • neuropeptides
  • concentration
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