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Mechanochemical syntheses and 35Cl solid-state NMR characterization of fluoxetine HCl cocrystals

Fluoxetine hydrochloride, the active pharmaceutical ingredient (API) in the antidepressant Prozac®, can form cocrystals with numerous organic acid coformers. The solvothermal syntheses of cocrystals with (i) fumaric acid, (ii) benzoic acid, and (iii) succinic acid coformers were first reported by Childs et a

Authors:   Austin A. Peach; David A. Hirsh; Sean T. Holmes; Robert W. Schurko
Journal:   CrystEngComm
Volume:   20
edition:   20
Pages:   2780
DOI:   10.1039/C8CE00378E
Facts, background information, dossiers
  • fluoxetine
  • benzoic acid
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