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Copper(I)/succinic acid cooperatively catalyzed one-pot synthesis of organoselenium-propargylamines via A3-coupling

Selenium propargylamines were synthesized via an A3-coupling approach using piperidine, p-methoxybenzaldehyde, and trimethylsilyl selenium–acetylene, catalyzed by copper(i) chloride and succinic acid as an additive, in good to excellent yields. This method is advantageous in that desilylation of the trimethylsilyl

Authors:   Isadora M. de Oliveira; Daniel C. Pimenta; Julio Zukerman-Schpector; Hélio A. Stefani; Flávia Manarin
Journal:   New Journal of Chemistry
DOI:   10.1039/C8NJ01543K
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