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Design and synthesis of novel monoterpenoid indole alkaloids-like analogues and their antitumour activities in vitro

A biomimetic synthetic strategy and combinatorial chemistry were used to synthesize 34 novel monoterpenoid indole alkaloid (MIA) analogues, and their cytotoxic activities against five cancer cell lines (SW-480, A-549, HL-60, SMMC-7721, and MCF-7) were determined using the 3-(4,5-dimethylthiazol-2-yl)-5-(3-ca

Authors:   Jiaqi Fang; Tao Huang; Mengyuan Xia; Lulu Deng; Xiaojiang Hao; Yuehu Wang; Shuzhen Mu
Journal:   Organic & Biomolecular Chemistry
Volume:   16
edition:   16
Pages:   3026
DOI:   10.1039/C8OB00677F
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