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Molbank, Vol. 2018, Article M991: 1-[1-(4-Chlorobenzenesulfonyl)-1H-indole-3-yl]-3-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

Molbank, Vol. 2018, Article M991: 1-[1-(4-Chlorobenzenesulfonyl)-1H-indole-3-yl]-3-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

Molbank doi: 10.3390/M991

Authors: Benjamín Diethelm Sebastián Almendras Gonzalo Recabarren-Gajardo

The title compound was prepared by an aza-Michael addition reaction between 1-[1-(4-chlorobenzenesulfonyl)-1H-indole-3-yl]prop-2-en-1-one and 2-piridylpiperazine catalyzed by SiO2. The structural identity of the title compound was proven by elemental analysis and spectroscopic methods (IR, NMR). The compound was assayed in a binding assay at the 5-HT6 receptor, showing poor affinity.

Authors:   Diethelm, Benjamín ; Almendras, Sebastián ; Recabarren-Gajardo, Gonzalo
Journal:   Molbank
Volume:   2018
edition:   2
Year:   2018
Pages:   M991
DOI:   10.3390/M991
Publication date:   18-Apr-2018
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