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Molecules, Vol. 23, Pages 1067: Xanthones Content in Swertia multicaulis D. Don from Nepal

Molecules, Vol. 23, Pages 1067: Xanthones Content in Swertia multicaulis D. Don from Nepal

Molecules doi: 10.3390/molecules23051067

Authors: Binu Timsina Pavel Kindlmann Maan B. Rokaya Naděžda Vrchotová Jan Tříska Štěpán Horník Jan Sýkora

The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. multicaulis was achieved by a combination of HPLC, LC–MS and LC–NMR. The final assignment of the individual chemical structures was provided by NMR, supported by preparative HPLC. In eight chromatographic peaks, four major xanthones were identified—1,3-dihydroxy-5,8-dimethoxyxanthone, 1-hydroxy-3,5,8-trimethoxyxanthone, bellidifolin (1,5,8-tri-hydroxy-3-methoxyxanthone), and decussatin (1-hydroxy-3,7,8-trimethoxyxanthone).

Authors:   Timsina, Binu ; Kindlmann, Pavel ; Rokaya, Maan B.; Vrchotová, Naděžda ; Tříska, Jan ; Horník, Štěpán ; Sýkora, Jan
Journal:   Molecules
Volume:   23
edition:   5
Year:   2018
Pages:   1067
DOI:   10.3390/molecules23051067
Publication date:   03-May-2018
Facts, background information, dossiers
  • ethyl acetate
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