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Molecules, Vol. 23, Pages 1285: Scabiosa stellata L. Phenolic Content Clarifies Its Antioxidant Activity

Molecules, Vol. 23, Pages 1285: Scabiosa stellata L. Phenolic Content Clarifies Its Antioxidant Activity

Molecules doi: 10.3390/molecules23061285

Authors: Naima Rahmouni Diana C. G. A. Pinto Noureddine Beghidja Samir Benayache Artur M. S. Silva

The phenolic profile of Scabiosa stellata L., a species used in Moroccan traditional medicine, is disclosed. To obtain that profile the species extract was analyzed by ultra-high-performance chromatography coupled to photodiode-array detection and electrospray ionization/ion trap mass spectrometry (UHPLC-DAD-ESI/MSn). Twenty-five phenolic compounds were identified from which isoorientin and 4-O-caffeoylquinic acid can be highlighted because they are the major ones. The antioxidant activity was significantly controlled by the fraction type, with the n-butanol fraction showing the highest antioxidant activity (FRS50 = 64.46 µg/mL in the DPPH assay, FRS50 = 27.87 µg/mL in the ABTS assay and EC50 = 161.11 µg/mL in the reducing power assay). A phytochemical study of the n-butanol fraction was performed, and some important flavone glycosides were isolated. Among them the tamarixetin derivatives—the less common ones—can be emphasized. This phytochemical study and polyphenolic profile can be correlated with S. stellata extracts in vitro antioxidant activity. Moreover, it can be regarded as an evidence of its medicinal use and can incentivize its consumption.

Authors:   Rahmouni, Naima ; Pinto, Diana C. G. A.; Beghidja, Noureddine ; Benayache, Samir ; Silva, Artur M. S.
Journal:   Molecules
Volume:   23
edition:   6
Year:   2018
Pages:   1285
DOI:   10.3390/molecules23061285
Publication date:   27-May-2018
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