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The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Technique Applied to the Study of Membrane-Active Peptides

Torsten John, Bernd Abel, Lisandra L. Martin

The biophysical technique of a quartz crystal microbalance with dissipation monitoring (QCM-D) enables the study of membrane-active biomolecules, such as antimicrobial or amyloidogenic peptides. This article provides an overview of the QCM-D technique and its capabilities for a comprehensive study of peptide–membrane interactions. QCM-D is a label-free, in vitro method that can detect membrane interactions in real-time and with nanogram sensitivity.


Authors:   ie=edge
Journal:   Australian Journal of Chemistry
Year:   2018
DOI:   10.1071/CH18129
Publication date:   15-Jun-2018
Facts, background information, dossiers
  • QCM
  • peptides
  • interactions
  • biomolecules
  • Abel
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