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Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles

Coiled-coil peptides have proven useful in a range of materials applications ranging from the formation of well-defined fibrils to responsive hydrogels. The ability to design from first principles their oligomerization and subsequent higher order assembly offers their expanded use in producing new materials.

Authors:   Michael John Haider; Huixi Violet Zhang; Nairiti J Sinha; Jeffrey Fagan; Kristi Kiick; Jeffery G. Saven; Darrin Pochan
Journal:   Soft Matter
DOI:   10.1039/C8SM00435H
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  • fibrils
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