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A Robust Split-Luciferase-Based Cell Fusion Screening for Discovering Myogenesis-Promoting Molecules

Myogenesis-promoting chemicals are an important source of new pharmaceuticals for the treatment of skeletal muscle atrophy that impairs quality of life. This report presents a robust and quantitative bioluminescence-based assay for screening myogenesis-promoting compounds in chemical libraries. The assay sys

Authors:   Qiaojing Li; Hideaki Yoshimura; Maki Komiya; Ken Tajiri; Motonari Uesugi; Yutaka Hata; Takeaki Ozawa
Journal:   Analyst
DOI:   10.1039/C8AN00285A
Facts, background information, dossiers
  • pharmaceuticals
  • molecules
  • luciferase
  • bioluminescence
  • atrophy
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