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Probing Propeller-Like Loops of DNA G-quadruplexes with Looped-Out 2-Aminopurine for Label-Free Switchable Molecular Sensing

We report a new signal readout mechanism for DNA molecular sensing devices using ligand-free fluorogenic G-quadruplexes of which the propeller-like loops are distinguished from the diagonal and lateral ones with incorporated 2-aminopurine (2-AP, a fluorescent analogue of adenine). We study the fluorescence b

Authors:   Pai Peng; Yi Du; Yudie Sun; Shuangna Liu; Lan Mi; Tao Li
Journal:   Analyst
DOI:   10.1039/C8AN00914G
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